Shengdar Q Tsai

Ontology type: schema:Person     

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Shengdar Q



Publications in SciGraph latest 50 shown

  • 2018-12 Illuminating the genome-wide activity of genome editors for safe and effective therapeutics in GENOME BIOLOGY
  • 2018-11 Defining CRISPR–Cas9 genome-wide nuclease activities with CIRCLE-seq in NATURE PROTOCOLS
  • 2018-09 In vivo CRISPR editing with no detectable genome-wide off-target mutations in NATURE
  • 2018-05 Corrigendum: CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets in NATURE METHODS
  • 2017-12 Towards safe therapy for immunodeficiency in NATURE BIOMEDICAL ENGINEERING
  • 2017-11-08 Circularization for In vitro Reporting of Cleavage Effects (CIRCLE-seq) in PROTOCOL EXCHANGE
  • 2017-06 CIRCLE-seq: a highly sensitive in vitro screen for genome-wide CRISPR–Cas9 nuclease off-targets in NATURE METHODS
  • 2016-08 Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells in NATURE BIOTECHNOLOGY
  • 2016-05 Open-source guideseq software for analysis of GUIDE-seq data in NATURE BIOTECHNOLOGY
  • 2016-05 Defining and improving the genome-wide specificities of CRISPR-Cas9 nucleases in NATURE REVIEWS GENETICS
  • 2016-01 High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects in NATURE
  • 2015-12 Broadening the targeting range of Staphylococcus aureus CRISPR-Cas9 by modifying PAM recognition in NATURE BIOTECHNOLOGY
  • 2015-10 Continuous directed evolution of DNA-binding proteins to improve TALEN specificity in NATURE METHODS
  • 2015-06-22 Engineered CRISPR-Cas9 nucleases with altered PAM specificities in NATURE
  • 2015-05 Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells in NATURE GENETICS
  • 2015-03 GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases in NATURE BIOTECHNOLOGY
  • 2014-10 Genome Editing: A Tool For Research and Therapy: Towards a functional understanding of variants for molecular diagnostics using genome editing in NATURE MEDICINE
  • 2014-06 Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing in NATURE BIOTECHNOLOGY
  • 2014-04 Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity in NATURE METHODS
  • 2013-12 Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins in NATURE BIOTECHNOLOGY
  • 2013-03 Efficient genome editing in zebrafish using a CRISPR-Cas system in NATURE BIOTECHNOLOGY
  • 2012-05 FLASH assembly of TALENs for high-throughput genome editing in NATURE BIOTECHNOLOGY
  • 2008-12 Identification of SNPs and INDELS in swine transcribed sequences using short oligonucleotide microarrays in BMC GENOMICS
  • 2006-12 Detection of transcriptional difference of porcine imprinted genes using different microarray platforms in BMC GENOMICS
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