Heinz Josef Lenz


Ontology type: schema:Person     


Person Info

NAME

Heinz Josef

SURNAME

Lenz

Publications in SciGraph latest 50 shown

  • 2019-12 Shared heritability and functional enrichment across six solid cancers in NATURE COMMUNICATIONS
  • 2019-02 Safety and Tolerability of c-MET Inhibitors in Cancer in DRUG SAFETY
  • 2018-12 Impact of primary tumour location on efficacy of bevacizumab plus chemotherapy in metastatic colorectal cancer in BRITISH JOURNAL OF CANCER
  • 2018-12 Molecular biomarkers in gastro-esophageal cancer: recent developments, current trends and future directions in CANCER CELL INTERNATIONAL
  • 2018-12 Management of Advanced Small Bowel Cancer in CURRENT TREATMENT OPTIONS IN ONCOLOGY
  • 2018-10 First-in-human phase I dose escalation study of MK-8033 in patients with advanced solid tumors in INVESTIGATIONAL NEW DRUGS
  • 2018-09 Potential role of PIN1 genotypes in predicting benefit from oxaliplatin-based and irinotecan-based treatment in patients with metastatic colorectal cancer in THE PHARMACOGENOMICS JOURNAL
  • 2018-05 A phase I trial of escalating doses of cixutumumab (IMC-A12) and sorafenib in the treatment of advanced hepatocellular carcinoma in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2018-04 A phase 1 dose-escalation study of veliparib with bimonthly FOLFIRI in patients with advanced solid tumours in BRITISH JOURNAL OF CANCER
  • 2018-03 Prognostic impact of FOXF1 polymorphisms in gastric cancer patients in THE PHARMACOGENOMICS JOURNAL
  • 2018-02-01 DNA methylation aberrancies delineate clinically distinct subsets of colorectal cancer and provide novel targets for epigenetic therapies in ONCOGENE
  • 2018-01 A genetic variant in Rassf1a predicts outcome in mCRC patients treated with cetuximab plus chemotherapy: results from FIRE-3 and JACCRO 05 and 06 trials in THE PHARMACOGENOMICS JOURNAL
  • 2018-01 Determination of an optimal response cut-off able to predict progression-free survival in patients with well-differentiated advanced pancreatic neuroendocrine tumours treated with sunitinib: an alternative to the current RECIST-defined response in BRITISH JOURNAL OF CANCER
  • 2018-01 Clinical relevance of EMT and stem-like gene expression in circulating tumor cells of metastatic colorectal cancer patients in THE PHARMACOGENOMICS JOURNAL
  • 2017-12 Randomized study of etirinotecan pegol versus irinotecan as second-line treatment for metastatic colorectal cancer in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2017-12 Germline polymorphisms as biomarkers of tumor response in colorectal cancer patients treated with anti-EGFR monoclonal antibodies: a systematic review and meta-analysis in THE PHARMACOGENOMICS JOURNAL
  • 2017-12 Molecular Landscape and Treatment Options for Patients with Metastatic Colorectal Cancer in INDIAN JOURNAL OF SURGICAL ONCOLOGY
  • 2017-12 CXCR4 polymorphism predicts progression-free survival in metastatic colorectal cancer patients treated with first-line bevacizumab-based chemotherapy in THE PHARMACOGENOMICS JOURNAL
  • 2017-12 Genetic variations in immunomodulatory pathways to predict survival in patients with locoregional gastric cancer in THE PHARMACOGENOMICS JOURNAL
  • 2017-11-28 Colorectal cancer in 2017: Practice-changing updates in the adjuvant and metastatic setting in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2017-06 What We Know About Stage II and III Colon Cancer: It’s Still Not Enough in TARGETED ONCOLOGY
  • 2017-03 What roles do colon stem cells and gap junctions play in the left and right location of origin of colorectal cancers? in JOURNAL OF CELL COMMUNICATION AND SIGNALING
  • 2017-01 Genetic variants associated with colorectal brain metastases susceptibility and survival in THE PHARMACOGENOMICS JOURNAL
  • 2017 VEGF Ligands in CANCER THERAPEUTIC TARGETS
  • 2017-01 Estrogen receptor-beta genetic variations and overall survival in patients with locally advanced gastric cancer in THE PHARMACOGENOMICS JOURNAL
  • 2016-08 Germline polymorphisms in genes involved in the Hippo pathway as recurrence biomarkers in stages II/III colon cancer in THE PHARMACOGENOMICS JOURNAL
  • 2016-05 Overcoming resistance to anti-EGFR therapy — where do we stand? in NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
  • 2016 VEGF Ligands in CANCER THERAPEUTIC TARGETS
  • 2016 Overview of Oncology Biomarkers in PHARMACOKINETICS IN DRUG DEVELOPMENT
  • 2015-12 Variations in genes involved in immune response checkpoints and association with outcomes in patients with resected colorectal liver metastases in THE PHARMACOGENOMICS JOURNAL
  • 2015-11 Pharmacodynamics (PD) and pharmacokinetics (PK) of E7389 (eribulin, halichondrin B analog) during a phase I trial in patients with advanced solid tumors: a California Cancer Consortium trial in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2015-10 LGR5 rs17109924 is a predictive genetic biomarker for time to recurrence in patients with colon cancer treated with 5-fluorouracil-based adjuvant chemotherapy in THE PHARMACOGENOMICS JOURNAL
  • 2015-09 Non-coding RNAs derived from an alternatively spliced REST transcript (REST-003) regulate breast cancer invasiveness in SCIENTIFIC REPORTS
  • 2015-08 Distinct gene expression profiles of proximal and distal colorectal cancer: implications for cytotoxic and targeted therapy in THE PHARMACOGENOMICS JOURNAL
  • 2015-06 The Molecular Taxonomy of Colorectal Cancer: What’s New? in CURRENT COLORECTAL CANCER REPORTS
  • 2015-06 Pharmacodynamic separation of gemcitabine and erlotinib in locally advanced or metastatic pancreatic cancer: therapeutic and biomarker results in INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY
  • 2015-06 Integrin genetic variants and stage-specific tumor recurrence in patients with stage II and III colon cancer in THE PHARMACOGENOMICS JOURNAL
  • 2015-06 Genetic variants of kinase suppressors of Ras (KSR1) to predict survival in patients with ERα-positive advanced breast cancer in THE PHARMACOGENOMICS JOURNAL
  • 2015-04 Molecular Classification of Gastric Adenocarcinoma: Translating New Insights from The Cancer Genome Atlas Research Network in CURRENT TREATMENT OPTIONS IN ONCOLOGY
  • 2015-04 KSR1 regulates BRCA1 degradation and inhibits breast cancer growth in ONCOGENE
  • 2015-03 A phase I, pharmacokinetic, and pharmacodynamic evaluation of the DNA methyltransferase inhibitor 5-fluoro-2′-deoxycytidine, administered with tetrahydrouridine in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2015-03 Circulating cytokines and monocyte subpopulations as biomarkers of outcome and biological activity in sunitinib-treated patients with advanced neuroendocrine tumours in BRITISH JOURNAL OF CANCER
  • 2015-02 Genes involved in pericyte-driven tumor maturation predict treatment benefit of first-line FOLFIRI plus bevacizumab in patients with metastatic colorectal cancer in THE PHARMACOGENOMICS JOURNAL
  • 2015-01 Erratum to: Phase II study of selumetinib (AZD6244, ARRY-142886) plus irinotecan as second-line therapy in patients with K-RAS mutated colorectal cancer in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2014-12 Phase I study of the halichondrin B analogue eribulin mesylate in combination with cisplatin in advanced solid tumors in BRITISH JOURNAL OF CANCER
  • 2014-08 Phase 1/2 study of KRN330, a fully human anti-A33 monoclonal antibody, plus irinotecan as second-line treatment for patients with metastatic colorectal cancer in INVESTIGATIONAL NEW DRUGS
  • 2014-08 Prospective study of EGFR intron 1 (CA)n repeats variants as predictors of benefit from cetuximab and irinotecan in chemo-refractory metastatic colorectal cancer (mCRC) patients in THE PHARMACOGENOMICS JOURNAL
  • 2014-05 Standing the test of time: targeting thymidylate biosynthesis in cancer therapy in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2014-04 The cyclin D1 (CCND1) rs9344 G>A polymorphism predicts clinical outcome in colon cancer patients treated with adjuvant 5-FU-based chemotherapy in THE PHARMACOGENOMICS JOURNAL
  • 2014-04 Gender-specific profiling in SCN1A polymorphisms and time-to-recurrence in patients with stage II/III colorectal cancer treated with adjuvant 5-fluoruracil chemotherapy in THE PHARMACOGENOMICS JOURNAL
  • Affiliations

  • University of Southern California (current)
  • National Cancer Institute
  • Hamilton Health Sciences
  • University of Arizona
  • Rocky Mountain Cancer Centers
  • University of Pittsburgh Cancer Institute
  • Bristol-Myers Squibb (United States)
  • University of Chicago
  • Northwestern University
  • Medical University of Graz
  • Massachusetts General Hospital
  • Dana–Farber Cancer Institute
  • Hospital Clinic of Barcelona
  • Kyoto University Hospital
  • Universitaire Ziekenhuizen Leuven
  • Case Western Reserve University
  • University of California, Davis
  • The University of Texas Health Science Center at San Antonio
  • Cancer Research And Biostatistics
  • Cornell University
  • Lakeland Regional Medical Center
  • Ruhr University Bochum
  • The University of Texas MD Anderson Cancer Center
  • University of North Carolina at Chapel Hill
  • Klinikum Kassel
  • Pfizer (United States)
  • Columbus Community Clinical Oncology Program
  • Centre Hospitalier Universitaire de Besançon
  • Beth Israel Deaconess Medical Center
  • Wayne State University
  • National Cancer Center Hospital East
  • Walter Reed National Military Medical Center
  • Loyola University Chicago
  • Medical University of Vienna
  • UC Davis Health System
  • University of California, San Francisco
  • Illinois CancerCare
  • Second University of Naples
  • University of New Mexico
  • University of Pennsylvania
  • Sylvester Comprehensive Cancer Center
  • University of Alabama at Birmingham
  • Albert Einstein College of Medicine
  • Merck (Germany)
  • Mayo Clinic
  • National Cancer Centre
  • University of Wisconsin Hospital and Clinics
  • University of North Carolina System
  • Centre Antoine Lacassagne
  • Memorial Sloan Kettering Cancer Center
  • Kindai University
  • Azusa Pacific University
  • Ospedale San Martino
  • Marqués de Valdecilla University Hospital
  • University Hospital in Motol
  • Swedish Medical Center
  • Institute of Oncology Ljubljana
  • Southwest Oncology Group
  • Temple University Health System
  • Wake Forest University
  • New York University
  • Washington University in St. Louis
  • St Joseph Mercy Hospital
  • University of Kansas
  • Princess Margaret Cancer Centre
  • City Of Hope National Medical Center
  • Kaiser Permanente Vallejo Medical Center
  • Sarah Cannon
  • JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

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