Michael O Hottiger

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Person Info


Michael O



Publications in SciGraph latest 50 shown

  • 2018-12 Validation of extracellular ligand–receptor interactions by Flow-TriCEPS in BMC RESEARCH NOTES
  • 2018-08-11 Mono-ADP-Ribosylhydrolase Assays in ADP-RIBOSYLATION AND NAD+ UTILIZING ENZYMES
  • 2017-12 Proteomic analyses identify ARH3 as a serine mono-ADP-ribosylhydrolase in NATURE COMMUNICATIONS
  • 2017-12 Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage in SCIENTIFIC REPORTS
  • 2017-12 Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia in SCIENTIFIC REPORTS
  • 2017-08-24 ADP-ribose-specific chromatin-affinity purification for investigating genome-wide or locus-specific chromatin ADP-ribosylation in NATURE PROTOCOLS
  • 2017 Identification of ADP-Ribose Acceptor Sites on In Vitro Modified Proteins by Liquid Chromatography–Tandem Mass Spectrometry in POLY(ADP-RIBOSE) POLYMERASE
  • 2017 Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography–Tandem Mass Spectrometry in POLY(ADP-RIBOSE) POLYMERASE
  • 2016-09-30 Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue in NATURE COMMUNICATIONS
  • 2016-09 A continuous sirtuin activity assay without any coupling to enzymatic or chemical reactions in SCIENTIFIC REPORTS
  • 2016-08 ARTD1 regulates osteoclastogenesis and bone homeostasis by dampening NF-κB-dependent transcription of IL-1β in SCIENTIFIC REPORTS
  • 2016-03 Poly-ADP-ribosylation-mediated degradation of ARTD1 by the NLRP3 inflammasome is a prerequisite for osteoclast maturation in CELL DEATH & DISEASE
  • 2013-12 Crosstalk between SET7/9-dependent methylation and ARTD1-mediated ADP-ribosylation of histone H1.4 in EPIGENETICS & CHROMATIN
  • 2013-08 Hyaluronic acid fragments enhance the inflammatory and catabolic response in human intervertebral disc cells through modulation of toll-like receptor 2 signalling pathways in ARTHRITIS RESEARCH & THERAPY
  • 2013-04 Macrodomain-containing proteins are new mono-ADP-ribosylhydrolases in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2013-02 PKC signaling prevents irradiation-induced apoptosis of primary human fibroblasts in CELL DEATH & DISEASE
  • 2011-04 HDAC-mediated deacetylation of NF-κB is critical for Schwann cell myelination in NATURE NEUROSCIENCE
  • 2011 Identification of Distinct Amino Acids as ADP-Ribose Acceptor Sites by Mass Spectrometry in POLY(ADP-RIBOSE) POLYMERASE
  • 2010-12 Acetylation of p65 at lysine 314 is important for late NF-κB-dependent gene expression in BMC GENOMICS
  • 2009-09 A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2009-04 Isolation, establishment, and characterization of ex vivo equine melanoma cell cultures in IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY - ANIMAL
  • 2008-12 Importin alpha binding and nuclear localization of PARP-2 is dependent on lysine 36, which is located within a predicted classical NLS in BMC CELL BIOLOGY
  • 2006 PARP-1 as Novel Coactivator of NF-κB in Inflammatory Disorders in POLY(ADP-RIBOSYL)ATION
  • 2003-11 PARP-1 binds E2F-1 independently of its DNA binding and catalytic domains, and acts as a novel coactivator of E2F-1-mediated transcription during re-entry of quiescent cells into S phase in ONCOGENE
  • 2002-10 The functional role of poly(ADP-ribose)polymerase 1 as novel coactivator of NF-κB in inflammatory disorders in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2002-08 Histone acetyl transferases: a role in DNA repair and DNA replication in JOURNAL OF MOLECULAR MEDICINE
  • 2001-03 Transcription coactivator p300 binds PCNA and may have a role in DNA repair synthesis in NATURE
  • 1999-12 p53 inhibition by the LANA protein of KSHV protects against cell death in NATURE
  • 1999-12 Liposome-mediated gene transfer into human basal cell carcinoma in GENE THERAPY
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