Robert I Nicholson


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Person Info

NAME

Robert I

SURNAME

Nicholson

Publications in SciGraph latest 50 shown

  • 2018-12 Correction to: Heregulin β1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells in BREAST CANCER RESEARCH
  • 2015-12 DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer in NATURE COMMUNICATIONS
  • 2014-02 Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro in BREAST CANCER RESEARCH
  • 2013-04 A randomized trial to assess the biological activity of short-term (pre-surgical) fulvestrant 500 mg plus anastrozole versus fulvestrant 500 mg alone or anastrozole alone on primary breast cancer in BREAST CANCER RESEARCH
  • 2012-12 Overexpression of CD44 accompanies acquired tamoxifen resistance in MCF7 cells and augments their sensitivity to the stromal factors, heregulin and hyaluronan in BMC CANCER
  • 2012-05 Dose-dependent change in biomarkers during neoadjuvant endocrine therapy with fulvestrant: results from NEWEST, a randomized Phase II study in BREAST CANCER RESEARCH AND TREATMENT
  • 2011-10 erbB3 recruitment of insulin receptor substrate 1 modulates insulin-like growth factor receptor signalling in oestrogen receptor-positive breast cancer cell lines in BREAST CANCER RESEARCH
  • 2011-04 Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin β1 in BREAST CANCER RESEARCH
  • 2011-02 Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells in BREAST CANCER RESEARCH AND TREATMENT
  • 2010-02 Growth of hormone-dependent MCF-7 breast cancer cells is promoted by constitutive caveolin-1 whose expression is lost in an EGF-R-mediated manner during development of tamoxifen resistance in BREAST CANCER RESEARCH AND TREATMENT
  • 2010-01 Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen in BREAST CANCER RESEARCH AND TREATMENT
  • 2009-05 Dual targeting of Src and ER prevents acquired antihormone resistance in breast cancer cells in BREAST CANCER RESEARCH AND TREATMENT
  • 2009-02 Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen in NATURE
  • 2009 Experimental Endocrine Resistance: Concepts and Strategies in THERAPEUTIC RESISTANCE TO ANTI-HORMONAL DRUGS IN BREAST CANCER
  • 2009 The Dark Side of Antihormonal Action in Breast Cancer in THERAPEUTIC RESISTANCE TO ANTI-HORMONAL DRUGS IN BREAST CANCER
  • 2009 Adverse Features of Acquired Antihormone Resistance and Their Targeting in THERAPEUTIC RESISTANCE TO ANTI-HORMONAL DRUGS IN BREAST CANCER
  • 2008-12 Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen in NATURE
  • 2008-12 Anti-oestrogens but not oestrogen deprivation promote cellular invasion in intercellular adhesion-deficient breast cancer cells in BREAST CANCER RESEARCH
  • 2008-11 In Vitro Effects on MCF-7 Breast Cancer Cells Of Signal Transduction Inhibitor/Tamoxifen/Eicosapentaenoic Acid Combinations and their Simultaneous Delivery Across Skin in PHARMACEUTICAL RESEARCH
  • 2008-09 Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib (‘Iressa’) response and resistance in BREAST CANCER RESEARCH AND TREATMENT
  • 2008-05 Anti-oestrogen therapy switches off tumour suppressors and proapoptotic genes in breast cancer and reveals a new therapeutic opportunity in BREAST CANCER RESEARCH
  • 2008-05 Loss of oestrogen receptor alpha in long-term antioestrogen-resistant cells: reversal by a c-src inhibitor in BREAST CANCER RESEARCH
  • 2008-04 Evaluation of the current knowledge limitations in breast cancer research: a gap analysis in BREAST CANCER RESEARCH
  • 2007-09 Growth factor signalling in endocrine and anti-growth factor resistant breast cancer in REVIEWS IN ENDOCRINE AND METABOLIC DISORDERS
  • 2007-08 Heregulin β1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells in BREAST CANCER RESEARCH
  • 2007-07 The Emerging Role of the LIV-1 Subfamily of Zinc Transporters in Breast Cancer in MOLECULAR MEDICINE
  • 2007-05 Src kinase promotes adhesion-independent activation of FAK and enhances cellular migration in tamoxifen-resistant breast cancer cells in CLINICAL & EXPERIMENTAL METASTASIS
  • 2007 Endocrine resistance and breast cancer invasion in METASTASIS OF BREAST CANCER
  • 2006-07 Inhibition of insulin receptor isoform-A signalling restores sensitivity to gefitinib in previously de novo resistant colon cancer cells in BRITISH JOURNAL OF CANCER
  • 2006-06 Elevated Src activity promotes cellular invasion and motility in tamoxifen resistant breast cancer cells in BREAST CANCER RESEARCH AND TREATMENT
  • 2006-03 Bidirectional cross talk between ERα and EGFR signalling pathways regulates tamoxifen-resistant growth in BREAST CANCER RESEARCH AND TREATMENT
  • 2005-11-01 Measurement of Estrogen Receptor Status by Immunocytochemistry in Paraffin Wax Sections in BREAST CANCER RESEARCH PROTOCOLS
  • 2005-10 Biological characteristics of the pure antiestrogen fulvestrant: overcoming endocrine resistance in BREAST CANCER RESEARCH AND TREATMENT
  • 2005-10 Endocrine therapy – current benefits and limitations in BREAST CANCER RESEARCH AND TREATMENT
  • 2004-09 Increased Constitutive Activity of PKB/Akt in Tamoxifen Resistant Breast Cancer MCF-7 Cells in BREAST CANCER RESEARCH AND TREATMENT
  • 2004-08 Extreme growth factor signalling can promote oestrogen receptor-α loss: therapeutic implications in breast cancer in BREAST CANCER RESEARCH
  • 2004-05 Tamoxifen resistance in breast cancer cells is accompanied by an enhanced motile and invasive phenotype: Inhibition by gefitinib (`Iressa', ZD1839) in CLINICAL & EXPERIMENTAL METASTASIS
  • 2003-09 Oestrogen Receptor-Mediated Modulation of the EGFR/MAPK Pathway in Tamoxifen-Resistant MCF-7 Cells in BREAST CANCER RESEARCH AND TREATMENT
  • 2003-06 Expanding the therapeutic repertoire of epidermal growth factor receptor blockade: radiosensitization in BREAST CANCER RESEARCH
  • 2003-03 The Biology of Antihormone Failure in Breast Cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2001-01 Selection of Primary Breast Cancer Patients for Adjuvant Endocrine Therapy – is Oestrogen Receptor Alone Adequate? in BREAST CANCER RESEARCH AND TREATMENT
  • 2001-01 Change in Expression of ER, bcl-2 and MIB1 on Primary Tamoxifen and Relation to Response in ER Positive Breast Cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 1999 Molecular Mechanisms of Antiestrogen Action in ESTROGENS AND ANTIESTROGENS I
  • 1998-08 EMS1 gene expression in primary breast cancer: relationship to cyclin D1 and oestrogen receptor expression and patient survival in ONCOGENE
  • 1998 The Primary Use of Endocrine Therapies in ADJUVANT THERAPY OF PRIMARY BREAST CANCER VI
  • 1997-09 Predictors of response to second-line endocrine therapy for breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 1996-02 Effects of short-term antiestrogen treatment of primary breast cancer on estrogen receptor mRNA and protein expression and on estrogen-regulated genes in BREAST CANCER RESEARCH AND TREATMENT
  • 1996 Growth Factors and Modulation of Endocrine Response in Breast Cancer in HORMONES AND CANCER
  • 1994-06 Dual immunocytochemical analysis of oestrogen and epidermal growth factor receptors in human breast cancer in BRITISH JOURNAL OF CANCER
  • 1994-04 A dual immunocytochemical assay for oestrogen and epidermal growth factor receptors in tumour cell lines in JOURNAL OF MOLECULAR HISTOLOGY
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