Hans Clevers

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Publications in SciGraph latest 50 shown

  • 2019-01 Tales from the crypt: new insights into intestinal stem cells in NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY
  • 2018-12 Enterovirus 71 infection of human airway organoids reveals VP1-145 as a viral infectivity determinant in EMERGING MICROBES & INFECTIONS
  • 2018-12 Hematopoietic stem cells can differentiate into restricted myeloid progenitors before cell division in mice in NATURE COMMUNICATIONS
  • 2018-12 Automated brightfield morphometry of 3D organoid populations by OrganoSeg in SCIENTIFIC REPORTS
  • 2018-08 Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signalling gradient in NATURE CELL BIOLOGY
  • 2018-07 Organoids in cancer research in NATURE REVIEWS CANCER
  • 2018-07 Modelling Cryptosporidium infection in human small intestinal and lung organoids in NATURE MICROBIOLOGY
  • 2018-04 Intra-tumour diversification in colorectal cancer at the single-cell level in NATURE
  • 2018-03 Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models in CELL DEATH & DIFFERENTIATION
  • 2018-02 BRCA-deficient mouse mammary tumor organoids to study cancer-drug resistance in NATURE METHODS
  • 2018-01 Imaging organoids: a bright future ahead in NATURE METHODS
  • 2017-12-11 Studying cancer drug resistance using BRCA-deficient mouse mammary tumor organoids in PROTOCOL EXCHANGE
  • 2017-12-07 Measuring mutation accumulation in single human adult stem cells by whole-genome sequencing of organoid cultures in NATURE PROTOCOLS
  • 2017-11 Corrigendum: Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors in NATURE MEDICINE
  • 2017-10 Cancer stem cells revisited in NATURE MEDICINE
  • 2017-08-29 FANTOM5 CAGE profiles of human and mouse samples in SCIENTIFIC DATA
  • 2017-07 Beyond growth signaling: Paneth cells metabolically support ISCs in CELL RESEARCH
  • 2017-07 Stem cell-derived organoids and their application for medical research and patient treatment in JOURNAL OF MOLECULAR MEDICINE
  • 2017-05 Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling in NATURE
  • 2017-03-06 Lipid-mediated Wnt protein stabilization enables serum-free culture of human organ stem cells in NATURE COMMUNICATIONS
  • 2017-03 Functional redundancy between Apc and Apc2 regulates tissue homeostasis and prevents tumorigenesis in murine mammary epithelium in ONCOGENE
  • 2017-01-19 Erratum: Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells in NATURE IMMUNOLOGY
  • 2017-01 Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors in NATURE MEDICINE
  • 2016-12 Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells in NATURE IMMUNOLOGY
  • 2016-11 Designer matrices for intestinal stem cell and organoid culture in NATURE
  • 2016-10 Tissue-specific mutation accumulation in human adult stem cells during life in NATURE
  • 2016-08-25 Culture and establishment of self-renewing human and mouse adult liver and pancreas 3D organoids and their genetic manipulation in NATURE PROTOCOLS
  • 2016-04 Tissue-specific designs of stem cell hierarchies in NATURE CELL BIOLOGY
  • 2016-04 Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure in SCIENTIFIC REPORTS
  • 2016-03-09 Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation in NATURE COMMUNICATIONS
  • 2016-02-10 Visualization of a short-range Wnt gradient in the intestinal stem-cell niche in NATURE
  • 2016-02 Organoid culture systems for prostate epithelial and cancer tissue in NATURE PROTOCOLS
  • 2016 The Generation of Organoids for Studying Wnt Signaling in WNT SIGNALING
  • 2016 CRISPR/Cas9-Mediated Genome Editing of Mouse Small Intestinal Organoids in GASTROINTESTINAL PHYSIOLOGY AND DISEASES
  • 2016-01 Reparative inflammation takes charge of tissue regeneration in NATURE
  • 2015-09 Single-cell messenger RNA sequencing reveals rare intestinal cell types in NATURE
  • 2015-09 Development and application of human adult stem or progenitor cell organoids in NATURE REVIEWS NEPHROLOGY
  • 2015-09 Expanding intestinal stem cells in culture in CELL RESEARCH
  • 2015-05 Sequential cancer mutations in cultured human intestinal stem cells in NATURE
  • 2015 Generation and Analysis of Mouse Intestinal Tumors and Organoids Harboring APC and K-Ras Mutations in MOUSE MODELS OF CANCER
  • 2014-12 Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2 in NATURE COMMUNICATIONS
  • 2014-12 A20 controls intestinal homeostasis through cell-specific activities in NATURE COMMUNICATIONS
  • 2014-12 STRAD pseudokinases regulate axogenesis and LKB1 stability in NEURAL DEVELOPMENT
  • 2014-09 Genome sequencing of normal cells reveals developmental lineages and mutational processes in NATURE
  • 2014-09 Glial origin of mesenchymal stem cells in a tooth model system in NATURE
  • 2014-06 Whole-genome sequencing and comprehensive molecular profiling identify new driver mutations in gastric cancer in NATURE GENETICS
  • 2014-03 A promoter-level mammalian expression atlas in NATURE
  • 2014-03 Intestinal crypt homeostasis revealed at single-stem-cell level by in vivo live imaging in NATURE
  • 2014-03 Transcription factor achaete-scute homologue 2 initiates follicular T-helper-cell development in NATURE
  • 2014-01 Niche-independent high-purity cultures of Lgr5+ intestinal stem cells and their progeny in NATURE METHODS
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