Jan Balzarini


Ontology type: schema:Person     


Person Info

NAME

Jan

SURNAME

Balzarini

Publications in SciGraph latest 50 shown

  • 2015-01 Structural modification of diarylpyrimidine derivatives as HIV-1 reverse transcriptase inhibitors in MEDICINAL CHEMISTRY RESEARCH
  • 2014-07 Structural Analogs of Umifenovir. 1. Synthesis and Biological Activity of Ethyl 5-Hydroxy-1-Methyl-2-(Trans-2-Phenylcyclopropyl)-1H-Indole-3-Carboxylate in CHEMISTRY OF HETEROCYCLIC COMPOUNDS
  • 2014-02 Synthesis of thiocarbohydrazide and carbohydrazide derivatives as possible biologically active agents in MEDICINAL CHEMISTRY RESEARCH
  • 2014 The role of N -glycans of HIV-1 gp41 in virus infectivity and susceptibility to the suppressive effects of carbohydrate-binding agents in RETROVIROLOGY
  • 2013-12 Synthesis and Anti-HIV-1 Activity of 1-[ω-(Phenoxy)Alkyl and -Alkenyl]Uracil Derivatives in PHARMACEUTICAL CHEMISTRY JOURNAL
  • 2013-06 Methyl-2-arylidene hydrazinecarbodithioates: synthesis and biological activity in CHEMICAL PAPERS
  • 2012-12 A phenyl-thiadiazolylidene-amine derivative ejects zinc from retroviral nucleocapsid zinc fingers and inactivates HIV virions in RETROVIROLOGY
  • 2012-08 Synthesis, antimycobacterial, antiviral, antimicrobial activities, and QSAR studies of nicotinic acid benzylidene hydrazide derivatives in MEDICINAL CHEMISTRY RESEARCH
  • 2012-07 Isonicotinic acid hydrazide derivatives: synthesis, antimicrobial activity, and QSAR studies in MEDICINAL CHEMISTRY RESEARCH
  • 2011-12 Differences in the mannose oligomer specificities of the closely related lectins from Galanthus nivalis and Zea maysstrongly determine their eventual anti-HIV activity in RETROVIROLOGY
  • 2011-11 Synthesis and biological evaluation of some stilbene derivatives in MEDICINAL CHEMISTRY RESEARCH
  • 2010-11 Microwave-assisted synthesis of a novel class of imidazolylthiazolidin-4-ones and evaluation of its biological activities in MOLECULAR DIVERSITY
  • 2009-01 Modification of the antibiotic olivomycin I at the 2′-keto group of the side chain. Novel derivatives, antitumor and topoisomerase I-poisoning activity in THE JOURNAL OF ANTIBIOTICS
  • 2007-08 Targeting the glycans of glycoproteins: a novel paradigm for antiviral therapy in NATURE REVIEWS MICROBIOLOGY
  • 2007-01 Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants in GENE THERAPY
  • 2005-12 AlphaHGA; A New Antiviral Substance Against HIV Affecting Capsid Assembly in RETROVIROLOGY
  • 2002-09 Pronounced cytostatic activity and bystander effect of a novel series of fluorescent tricyclic acyclovir and ganciclovir derivatives in herpes simplex virus thymidine kinase gene-transduced tumor cell lines in GENE THERAPY
  • 2000-02 Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2′-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-β-D-arabinofuranosyluracil (BVaraU), against tumor cells expressing either the Varicella zoster or the Herpes simplex virus thymidine kinase in CANCER GENE THERAPY
  • 1999-09-14 Evaluating Clinical Isolates for Their Phenotypic and Genotypic Resistance Against Anti-HIV Drugs in ANTIVIRAL METHODS AND PROTOCOLS
  • 1998-03 Superior cytostatic activity of the ganciclovir elaidic acid ester due to the prolonged intracellular retention of ganciclovir anabolites in herpes simplex virus type 1 thymidine kinase gene-transfected tumor cells in GENE THERAPY
  • 1998-02 Improving AZT efficacy in NATURE MEDICINE
  • 1998 Metabolism of Eicar (5-Ethynyl-1-β-D- Ribofuranosylimidazole-4-Carboxamide),A Potent Inhibitor of Inosinate Dehydrogenase in PURINE AND PYRIMIDINE METABOLISM IN MAN IX
  • 1996-06 Molecular cloning of the lectin and a lectin-related protein from common Solomon's seal (Polygonatum multiflorum) in PLANT MOLECULAR BIOLOGY
  • 1994-08 The monomeric and dimeric mannose-binding proteins from the Orchidaceae speciesListera ovata andEpipactis helleborine: sequence homologies and differences in biological activities in GLYCOCONJUGATE JOURNAL
  • 1993-10 Cloning and characterization of the lectin cDNA clones from onion, shallot and leek in PLANT MOLECULAR BIOLOGY
  • 1993-08 Abstracts of oral presentations in INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
  • 1993-08 Key lectures in INTERNATIONAL JOURNAL OF CLINICAL PHARMACY
  • 1993 Inhibition of HIV Replication and Enhancement of Immune Functions by the Acyclic Nucleoside Phosphonate 9-(2-Phosphonyl-Methoxyethyl)Adenine (PMEA) in COMBINATION THERAPIES 2
  • 1992-12 Activity of different antiviral drug combinations against human cytomegalovirus replication in vitro in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
  • 1991 Conversion of Acyclic Nucleoside Phosphonates to Their Diphosphate Derivatives by 5-Phosphoribosyl-1-Pyrophosphate (PRPP) Synthetase in PURINE AND PYRIMIDINE METABOLISM IN MAN VII
  • 1989-12 9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine (PMEDAP): A novel agent with anti-human immunodeficiency virus activity in vitro and potent anti-moloney murine sarcoma virus activity in vivo in EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
  • 1989 The antiretroviral and cytostatic activity, and metabolism of 3'-azido-2',3'-dideoxythymidine, 3'-fluoro-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly cell type-dependent. in PURINE AND PYRIMIDINE METABOLISM IN MAN VI
  • 1986-10 A novel selective broad-spectrum anti-DNA virus agent in NATURE
  • 1984 Strategies in the Design of Oligonucleotides as Potential Antiviral Agents in TARGETS FOR THE DESIGN OF ANTIVIRAL AGENTS
  • 1983-06 Inhibitory activity of diarylamidine derivatives on murine leukemia L1210 cell growth in INVESTIGATIONAL NEW DRUGS
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