Steven M Paul


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Person Info

NAME

Steven M

SURNAME

Paul

Publications in SciGraph latest 50 shown

  • 2018-12 Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function in NATURE COMMUNICATIONS
  • 2015-12 Copy number variants encompassing Mendelian disease genes in a large multigenerational family segregating bipolar disorder in BMC GENETICS
  • 2015-10 Disruption of sonic hedgehog signaling in Ellis-van Creveld dwarfism confers protection against bipolar affective disorder in MOLECULAR PSYCHIATRY
  • 2015-09 Microglial internalization and degradation of pathological tau is enhanced by an anti-tau monoclonal antibody in SCIENTIFIC REPORTS
  • 2014-12 Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40 in MOLECULAR NEURODEGENERATION
  • 2010-03 How to improve R&D productivity: the pharmaceutical industry's grand challenge in NATURE REVIEWS DRUG DISCOVERY
  • 2004-07 Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-β peptides in NATURE MEDICINE
  • 2003 Effects of a Peripheral Anti-Aβ Antibody on Plasma and CNS Aβ Clearance in IMMUNIZATION AGAINST ALZHEIMER’S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS
  • 2002-05 Immunization reverses memory deficits without reducing brain Aβ burden in Alzheimer's disease model in NATURE NEUROSCIENCE
  • 2002-02 Role of apoE/Aβ interactions in Alzheimer's disease: insights from transgenic mouse models in MOLECULAR PSYCHIATRY
  • 2000-08 Apolipoprotein E affects the amount, form, and anatomical distribution of amyloid β-peptide deposition in homozygous APPV717F transgenic mice in ACTA NEUROPATHOLOGICA
  • 2000 Cytokine Communication Between Neurons and Glia and the Pathogenesis of Alzheimer’s Disease in NEURO-IMMUNE INTERACTIONS IN NEUROLOGIC AND PSYCHIATRIC DISORDERS
  • 2000 bcl-2 Protects SK-N-SH Cells From 6-Hydroxydopamine Induced Apoptosis by Inhibition of Cytochrome c Redistribution in NEUROTOXIC FACTORS IN PARKINSON’S DISEASE AND RELATED DISORDERS
  • 1998-03 Transient Global Forebrain Ischemia Induces a Prolonged Expression of the Caspase-3 mRNA in Rat Hippocampal CA1 Pyramidal Neurons in JOURNAL OF CEREBRAL BLOOD FLOW & METABOLISM
  • 1997-11 Lack of apolipoprotein E dramatically reduces amyloid β-peptide deposition in NATURE GENETICS
  • 1997-06-03 Molecular Strategies to Novel Antidepressant Discovery in ANTIDEPRESSANTS
  • 1997-05 Mapping Quantitative Trait Loci for Open-Field Behavior in Mice in BEHAVIOR GENETICS
  • 1997-03-01 Cultured Cerebellar Granule Neurons as a Model of Neuronal Apoptosis in APOPTOSIS TECHNIQUES AND PROTOCOLS
  • 1997 Molecular Strategies to Novel Antidepressant Discovery in ANTIDEPRESSANTS
  • 1996-08 The neurosteroid pregnenolone sulfate reduces learning deficits induced by scopolamine and has promnestic effects in mice performing an appetitive learning task in PSYCHOPHARMACOLOGY
  • 1996-07 7-Nitroindazole and Methylene Blue, Inhibitors of Neuronal Nitric Oxide Synthase and NO-Stimulated Guanylate Cyclase, Block MK-801-Elicited Behaviors in Mice in NEUROPSYCHOPHARMACOLOGY
  • 1996-04 A genome-wide search for chromosomal loci linked to bipolar affective disorder in the Old Order Amish in NATURE GENETICS
  • 1995-11 Genetic analysis of anxiety-related behaviors and responses to benzodiazepine-related drugs in AXB and BXA recombinant inbred mouse strains in BEHAVIOR GENETICS
  • 1994-10 The neurosteroid pregnenolone sulfate blocks NMDA antagonist-induced deficits in a passive avoidance memory task in PSYCHOPHARMACOLOGY
  • 1994-03 Characterization of benzodiazepine-sensitive behaviors in the A/J and C57BL/6J inbred strains of mice in BEHAVIOR GENETICS
  • 1993-07 Increased serum soluble interleukin-2 receptors in schizophrenic monozygotic twins in EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
  • 1991 Ethanol and the GABAA Receptor-Gated Chloride Ion Channel in NEUROPHARMACOLOGY OF ETHANOL
  • 1990-12 Gamma-aminobutyric acid (GABAA) receptor-function in a rat model of hepatic encephalopathy in METABOLIC BRAIN DISEASE
  • 1990-03 Tyrosine hydroxylase and cholecystokinin mRNA levels in the substantia nigra, ventral tegmental area, and locus ceruleus are unaffected by acute and chronic haloperidol administration in CELLULAR AND MOLECULAR NEUROBIOLOGY
  • 1989-11 Re-evaluation of the linkage relationship between chromosome 11p loci and the gene for bipolar affective disorder in the Old Order Amish in NATURE
  • 1988-11 Acute barbiturate administration increases benzodiazepine receptor binding in vivo in PSYCHOPHARMACOLOGY
  • 1988-03 Kinetics, brain uptake, and receptor binding characteristics of flurazepam and its metabolites in PSYCHOPHARMACOLOGY
  • 1988 The Benzodiazepine—GABA Receptor Complex in Experimental Stress, Anxiety and Depression in NEW CONCEPTS IN DEPRESSION
  • 1987-10 Sleep induction by an adrenal steroid in the rat in PSYCHOPHARMACOLOGY
  • 1987-09 Determinants of benzodiazepine brain uptake: lipophilicity versus binding affinity in PSYCHOPHARMACOLOGY
  • 1987-09 Environmentally-induced modification of the benzodiazepine/GABA receptor coupled chloride ionophore in PSYCHOPHARMACOLOGY
  • 1987 Pharmacodynamic Approaches to Benzodiazepine Action in Man in CLINICAL PHARMACOLOGY IN PSYCHIATRY
  • 1987 Modulation of the Benzodiazepine-GABA Receptor Chloride Ionophore Complex by Multiple Allosteric Sites: Evidence for a Barbiturate “Receptor” in CLINICAL PHARMACOLOGY IN PSYCHIATRY
  • 1987 A Physiological Role of the Benzodiazepine/GABA Receptor-Chloride Ionophore Complex in Stress in MOLECULAR MECHANISMS OF NEURONAL RESPONSIVENESS
  • 1987 Biochemical Alterations Produced by Neuroleptics in Man: Studies of Plasma Homovanillic Acid in Schizophrenic Patients in CLINICAL PHARMACOLOGY IN PSYCHIATRY
  • 1985 Neurotransmitter Receptor-Mediated Myo-Inositol 1-Phosphate Accumulation in Hippocampal Slices in INOSITOL AND PHOSPHOINOSITIDES
  • 1983-02 Sedative and electroencephalographic actions of erythro-9-(2-hydroxy-3-nonyl)-adenine (EHNA): Relationship to inhibition of brain adenosine deaminase in PSYCHOPHARMACOLOGY
  • 1983 Characterization of high-affinity antidepressant binding to rat and human brain in CLINICAL PHARMACOLOGY IN PSYCHIATRY
  • 1983 Benzodiazepine receptor-mediated experimental ‘anxiety’ in rhesus monkeys after infusion of 3-carboethoxy-ß-carboline (ß-CCE) in CLINICAL PHARMACOLOGY IN PSYCHIATRY
  • 1982-03 Nitroimipramines — Synthesis and pharmacological effects of potent long-acting inhibitors of [3H] serotonin uptake and [3H] imipramine binding in NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY
  • 1981-11 Anticonvulsant doses of inosine result in brain levels sufficient to inhibit [3H] diazepam binding in PSYCHOPHARMACOLOGY
  • 1981-04 Acceleration of β-receptor desensitization in combined administration of antidepressants and phenoxybenzamine in NATURE
  • 1981-03 The benzodiazepines and inosine antagonize caffeine-induced seizures in PSYCHOPHARMACOLOGY
  • 1981-01 Differential electrophysiological and behavioral responses to optically active derivatives of phencyclidine in NAUNYN-SCHMIEDEBERG'S ARCHIVES OF PHARMACOLOGY
  • 1979-10 Correlation between benzodiazepine receptor occupation and anticonvulsant effects of diazepam in NATURE
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