Eric B Kmiec

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Eric B



Publications in SciGraph latest 50 shown

  • 2017-04 To cleave or not to cleave: therapeutic gene editing with and without programmable nucleases in NATURE REVIEWS DRUG DISCOVERY
  • 2016-12 Analyses of point mutation repair and allelic heterogeneity generated by CRISPR/Cas9 and single-stranded DNA oligonucleotides in SCIENTIFIC REPORTS
  • 2015-05 Combinatorial gene editing in mammalian cells using ssODNs and TALENs in SCIENTIFIC REPORTS
  • 2011-10 Modifications of p53 and the DNA Damage Response in Cells Expressing Mutant Form of the Protein Huntingtin in JOURNAL OF MOLECULAR NEUROSCIENCE
  • 2009-12 Genetic correction of splice site mutation in purified and enriched myoblasts isolated from mdx5cv mice in BMC MOLECULAR BIOLOGY
  • 2007-12 Reduction of gene repair by selenomethionine with the use of single-stranded oligonucleotides in BMC MOLECULAR BIOLOGY
  • 2007-12 Manipulation of cell cycle progression can counteract the apparent loss of correction frequency following oligonucleotide-directed gene repair in BMC MOLECULAR BIOLOGY
  • 2007-12 Progress and Prospects: targeted gene alteration (TGA) in GENE THERAPY
  • 2006-12 Short G-rich oligonucleotides as a potential therapeutic for Huntington's Disease in BMC NEUROSCIENCE
  • 2005-04 Gene therapy progress and prospects: targeted gene repair in GENE THERAPY
  • 2005-03 Reaction parameters of targeted gene repair in mammalian cells in MOLECULAR BIOTECHNOLOGY
  • 2004-12-29 Enhancement of In Vivo Targeted Nucleotide Exchange by Nonspecific Carrier DNA in GENETIC RECOMBINATION
  • 2004-06 Modified single-stranded oligonucleotides inhibit aggregate formation and toxicity induced by expanded polyglutamine in JOURNAL OF MOLECULAR NEUROSCIENCE
  • 2004-06 Gene editing of a human gene in yeast artificial chromosomes using modified single-stranded DNA and dual targeting in THE PHARMACOGENOMICS JOURNAL
  • 2003-09 Biased gene repair needs unbiased review in NATURE REVIEWS GENETICS
  • 2003-09 The development and regulation of gene repair in NATURE REVIEWS GENETICS
  • 2002-01 Targeted beta-globin gene conversion in human hematopoietic CD34+ and Lin−CD38− cells in GENE THERAPY
  • 2001-04 The potential of nucleic acid repair in functional genomics in NATURE BIOTECHNOLOGY
  • 2000 Targeted Gene Repair in Mammalian Cells Using Chimeric Oligonucleotides in GENETIC ENGINEERING
  • 1999-09-23 Gene Targeting in Plants via Site-Directed Mutagenesis in GENE TARGETING PROTOCOLS
  • 1999-09-23 Optimizing Polyethylenimine-Based Gene Transfer into Mammalian Brain for Analysis of Promoter Regulation and Protein Function in GENE TARGETING PROTOCOLS
  • 1999-09-23 Gene Transfer and Drug Delivery by Electronic Pulse Delivery: A Nonviral Delivery Approach in GENE TARGETING PROTOCOLS
  • 1999-09-23 Site-Directed Alteration of Genomic DNA by Small-Fragment Homologous Replacement in GENE TARGETING PROTOCOLS
  • 1999-09-23 Triplex-Directed Site-Specific Genome Modification in GENE TARGETING PROTOCOLS
  • 1999-09-23 Use of Quantitative Ligation-Mediated Polymerase Chain Reaction to Detect Gene Targeting by Alkylating Oligodeoxynucleotides in GENE TARGETING PROTOCOLS
  • 1999-09-23 EBV-Derived Episomes to Probe Chromatin Structure and Gene Expression in Human Cells in GENE TARGETING PROTOCOLS
  • 1999-09-23 Nucleic Acid Transfer Using Cationic Lipids in GENE TARGETING PROTOCOLS
  • 1999-09-23 Effective Gene Transfer Using Viral Vectors Based on SV40 in GENE TARGETING PROTOCOLS
  • 1999-09-23 Rapid Generation of Isogenic Mammalian Cell Lines Expressing Recombinant Transgenes by Use of Cre Recombinase in GENE TARGETING PROTOCOLS
  • 1999-09-23 Adeno-Associated Virus Based Gene Therapy in Skeletal Muscle in GENE TARGETING PROTOCOLS
  • 1999-09-23 Antisense Oligonucleotides as Modulators of Pre-mRNA Splicing in GENE TARGETING PROTOCOLS
  • 1999-09-23 Strategies for Improving the Frequency and Assessment of Homologous Recombination in GENE TARGETING PROTOCOLS
  • 1999-09-23 Rapid Establishment of Myeloma Cell Lines Expressing Fab(Tac)-Protamine, a Targetable Protein Vector, Directed Against High-Affinity α-Chain of Human Interleukin-2 Receptor in GENE TARGETING PROTOCOLS
  • 1998-06 RecA-mediated joint molecule formation between O-methylated RNA/DNA hairpins and single-stranded targets in MOLECULAR GENETICS AND GENOMICS
  • 1998-01-21 Pathways of DNA Repair in Ustilago maydis in DNA DAMAGE AND REPAIR
  • 1998 Genetic Correction for Gene Therapy in GENE THERAPY
  • 1997-11 Targeted gene conversion in a mammalian CD34+-enriched cell population using a chimeric RNA/DNA oligonucleotide in JOURNAL OF MOLECULAR MEDICINE
  • 1996-03 RNA facilitates RecA-mediated DNA pairing and strand transfer between molecules bearing limited regions of homology in MOLECULAR GENETICS AND GENOMICS
  • 1995-10 Assembly of nucleosomal DNA in a cell-free extract from wild-type and top1− strains ofUstilago maydis in MOLECULAR GENETICS AND GENOMICS
  • 1994-11 DNA cruciforms facilitate in vitro strand transfer on nucleosomal templates in MOLECULAR GENETICS AND GENOMICS
  • 1994-07 Genetic recombination of nucleosomal templates is mediated by transcription in MOLECULAR GENETICS AND GENOMICS
  • 1993-05 The glucocorticoid receptor precludes the binding of a transcriptional repressor protein to the long terminal repeat of the mouse mammary tumor virus in MOLECULAR AND CELLULAR BIOCHEMISTRY
  • 1993-05 Purification and properties of a cruciform DNA binding protein fromUstilago maydis in CHROMOSOMA
  • 1993-03 In vitro transcription of the c-myc first exon may be influenced by the extent of chromatin assembly in MOLECULAR AND CELLULAR BIOCHEMISTRY
  • 1992-05 In vitro analysis of a type I DNA topoisomerase activity from cultured tobacco cells in PLANT MOLECULAR BIOLOGY
  • 1990-05 Cis-acting enhancement of RNA polymerase III gene expression in vitro in MOLECULAR GENETICS AND GENOMICS
  • 1989-12 DNA superhelicity enhances the assembly of transcriptionally active chromatin in vitro in MOLECULAR GENETICS AND GENOMICS
  • 1989-09 Changes in DNA topology can modulatein vitro transcription of certain RNA polymerase III genes in MOLECULAR AND CELLULAR BIOCHEMISTRY
  • 1988-10 Studies on DNA Topoisomerase activity during in vitro chromatin assembly in MOLECULAR AND CELLULAR BIOCHEMISTRY
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