Charles Swanton


Ontology type: schema:Person     


Person Info

NAME

Charles

SURNAME

Swanton

Publications in SciGraph latest 50 shown

  • 2019-03 Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions in NATURE MEDICINE
  • 2018-12 Publisher Correction: Genomic instability in mutant p53 cancer cells upon entotic engulfment in NATURE COMMUNICATIONS
  • 2018-12 Genomic instability in mutant p53 cancer cells upon entotic engulfment in NATURE COMMUNICATIONS
  • 2018-09 Early stage NSCLC — challenges to implementing ctDNA-based screening and MRD detection in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2018-01-03 Determinants and clinical implications of chromosomal instability in cancer in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2018-01 Chromosomal instability drives metastasis through a cytosolic DNA response in NATURE
  • 2017-12 Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling in NATURE COMMUNICATIONS
  • 2017-12 Quantification of tumour evolution and heterogeneity via Bayesian epiallele detection in BMC BIOINFORMATICS
  • 2017-12 The role of tumour heterogeneity and clonal cooperativity in metastasis, immune evasion and clinical outcome in BMC MEDICINE
  • 2017-12 Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers in NATURE GENETICS
  • 2017-09-15 Classifying the evolutionary and ecological features of neoplasms in NATURE REVIEWS CANCER
  • 2017-08-31 Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions in ONCOGENE
  • 2017-08-22 Evolution and cancer medicine — transformative insights in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2017-07-18 TRACERx Renal: tracking renal cancer evolution through therapy in NATURE REVIEWS UROLOGY
  • 2017-05 Spatial heterogeneity in medulloblastoma in NATURE GENETICS
  • 2017-04-28 Implications of cancer evolution for drug development in NATURE REVIEWS DRUG DISCOVERY
  • 2017-03-09 Renal cell carcinoma in NATURE REVIEWS DISEASE PRIMERS
  • 2017-02 Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions in ONCOGENE
  • 2016-12 deconstructSigs: delineating mutational processes in single tumors distinguishes DNA repair deficiencies and patterns of carcinoma evolution in GENOME BIOLOGY
  • 2016-12 DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer in GENOME BIOLOGY
  • 2016-12 A comprehensive survey of the mutagenic impact of common cancer cytotoxics in GENOME BIOLOGY
  • 2016-10 Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes in NATURE BIOTECHNOLOGY
  • 2016-07 RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress in ONCOGENE
  • 2016-07 RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress in ONCOGENE
  • 2015-12 Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution in NATURE COMMUNICATIONS
  • 2015-12 TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen in BMC MEDICAL GENOMICS
  • 2015-11 SETD2 loss-of-function promotes renal cancer branched evolution through replication stress and impaired DNA repair in ONCOGENE
  • 2015-10 Gastrointestinal cancer: Tracking tumour evolution through liquid biopsy in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2015-08 Toward understanding and exploiting tumor heterogeneity in NATURE MEDICINE
  • 2015-07 Clinical management of breast cancer heterogeneity in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2015-05 Can oncology recapitulate paleontology? Lessons from species extinctions in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2014-11 Expression of regulators of mitotic fidelity are associated with intercellular heterogeneity and chromosomal instability in primary breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2014-09 Deciphering clonality in aneuploid breast tumors using SNP array and sequencing data in GENOME BIOLOGY
  • 2014-08 Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine in GENOME BIOLOGY
  • 2014-08 Development of synchronous VHL syndrome tumors reveals contingencies and constraints to tumor evolution in GENOME BIOLOGY
  • 2014-03 Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing in NATURE GENETICS
  • 2014 Deciphering clonality in aneuploid tumors using SNP array and sequencing data in GENOME BIOLOGY
  • 2013-12 Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications in GENOME MEDICINE
  • 2013-12 A phase 1 study evaluating the combination of an allosteric AKT inhibitor (MK-2206) and trastuzumab in patients with HER2-positive solid tumors in BREAST CANCER RESEARCH
  • 2013-12 Computational optimisation of targeted DNA sequencing for cancer detection in SCIENTIFIC REPORTS
  • 2013-10 Patupilone in patients with pretreated metastatic/locally recurrent colorectal cancer: results of the Phase II CINATRA trial in INVESTIGATIONAL NEW DRUGS
  • 2013-10 HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis in NATURE
  • 2013-09 The causes and consequences of genetic heterogeneity in cancer evolution in NATURE
  • 2013-08 Corrigendum: Replication stress links structural and numerical cancer chromosomal instability in NATURE
  • 2013-06 Taxane benefit in breast cancer—a role for grade and chromosomal stability in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2013-04 A 3-gene proliferation score (TOP-FOX-67) can re-classify histological grade-2, ER-positive breast cancers into low- and high-risk prognostic categories in BREAST CANCER RESEARCH AND TREATMENT
  • 2013-02 Replication stress links structural and numerical cancer chromosomal instability in NATURE
  • 2013-02 Cancer heterogeneity: implications for targeted therapeutics in BRITISH JOURNAL OF CANCER
  • 2012-12 Personalization of prostate cancer prevention and therapy: are clinically qualified biomarkers in the horizon? in EPMA JOURNAL
  • 2012-12 Unlocking Pandora's box: personalising cancer cell death in non-small cell lung cancer in EPMA JOURNAL
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