Bernhard K Keppler


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Person Info

NAME

Bernhard K

SURNAME

Keppler

Publications in SciGraph latest 50 shown

  • 2018-12 Biological activity of PtIV prodrugs triggered by riboflavin-mediated bioorthogonal photocatalysis in SCIENTIFIC REPORTS
  • 2018-11 Critical assessment of different methods for quantitative measurement of metallodrug-protein associations in ANALYTICAL AND BIOANALYTICAL CHEMISTRY
  • 2018-11 The thiosemicarbazone Me2NNMe2 induces paraptosis by disrupting the ER thiol redox homeostasis based on protein disulfide isomerase inhibition in CELL DEATH & DISEASE
  • 2018-10 Understanding the interactions of diruthenium anticancer agents with amino acids in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2018-10 Serum-binding properties of isosteric ruthenium and osmium anticancer agents elucidated by SEC–ICP–MS in MONATSHEFTE FÜR CHEMIE - CHEMICAL MONTHLY
  • 2018-03 Comparison of metabolic pathways of different α-N-heterocyclic thiosemicarbazones in ANALYTICAL AND BIOANALYTICAL CHEMISTRY
  • 2017-12 Distinct activity of the bone-targeted gallium compound KP46 against osteosarcoma cells - synergism with autophagy inhibition in JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
  • 2017-12 Electronic State of Sodium trans-[Tetrachloridobis(1H-indazole)ruthenate(III)] (NKP-1339) in Tumor, Liver and Kidney Tissue of a SW480-bearing Mouse in SCIENTIFIC REPORTS
  • 2017-06 EGFR-targeting peptide-coupled platinum(IV) complexes in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2017-02 Loss of CUL4A expression is underlying cisplatin hypersensitivity in colorectal carcinoma cells with acquired trabectedin resistance in BRITISH JOURNAL OF CANCER
  • 2016-06 Molecular mode of action of NKP-1339 – a clinically investigated ruthenium-based drug – involves ER- and ROS-related effects in colon carcinoma cell lines in INVESTIGATIONAL NEW DRUGS
  • 2016-06 Biological properties of novel ruthenium- and osmium-nitrosyl complexes with azole heterocycles in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2015-08 Three-dimensional and co-culture models for preclinical evaluation of metal-based anticancer drugs in INVESTIGATIONAL NEW DRUGS
  • 2015-03 Extraction of natural radionuclides from aqueous solutions by novel maltolate-based task-specific ionic liquids in JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
  • 2015-01 Comparative in vitro and in vivo pharmacological investigation of platinum(IV) complexes as novel anticancer drug candidates for oral application in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2015-01 Interaction of the anticancer gallium(III) complexes of 8-hydroxyquinoline and maltol with human serum proteins in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2014-12 Modulation of Activity of Known Cytotoxic Ruthenium(III) Compound (KP418) with Hampered Transmembrane Transport in Electrochemotherapy In Vitro and In Vivo in THE JOURNAL OF MEMBRANE BIOLOGY
  • 2013-08 A systematic capillary electrophoresis study on the effect of the buffer composition on the reactivity of the anticancer drug cisplatin to the DNA model 2′-deoxyguanosine 5′-monophosphate (dGMP) in ANALYTICAL AND BIOANALYTICAL CHEMISTRY
  • 2013-05 Copper(II) complexes with derivatives of pyrazole as potential antioxidant enzyme mimics in MEDICINAL CHEMISTRY RESEARCH
  • 2013-02 Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2013 Osmium Complexes with Azole Heterocycles as Potential Antitumor Drugs in ENCYCLOPEDIA OF METALLOPROTEINS
  • 2013-01 Characterization of the binding sites of the anticancer ruthenium(III) complexes KP1019 and KP1339 on human serum albumin via competition studies in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2012-09 NKP-1339, a first-in-class anticancer drug showing mild side effects and activity in patients suffering from advanced refractory cancer in BMC PHARMACOLOGY AND TOXICOLOGY
  • 2012-06 Effect of reactivity on cellular accumulation and cytotoxicity of oxaliplatin analogues in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2012-03 Mechanisms underlying reductant-induced reactive oxygen species formation by anticancer copper(II) compounds in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2012-03 Cellular accumulation and DNA interaction studies of cytotoxic trans-platinum anticancer compounds in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2012-03 Fragmentation methods on the balance: unambiguous top–down mass spectrometric characterization of oxaliplatin–ubiquitin binding sites in ANALYTICAL AND BIOANALYTICAL CHEMISTRY
  • 2011-12 Influence of ascorbic acid on the activity of the investigational anticancer drug KP1019 in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2011-08 A polymer inclusion membrane based on the ionic liquid trihexyl(tetradecyl)phosphonium chloride and PVC for solid–liquid extraction of Zn(II) from hydrochloric acid solution in MONATSHEFTE FÜR CHEMIE - CHEMICAL MONTHLY
  • 2011-06 Lectin Conjugates as Biospecific Contrast Agents for MRI. Coupling of Lycopersicon esculentum Agglutinin to Linear Water-Soluble DTPA-Loaded Oligomers in MOLECULAR IMAGING AND BIOLOGY
  • 2011-02 Lectin–Gd-Loaded Chitosan Hydrogel Nanoparticles: A New Biospecific Contrast Agent for MRI in MOLECULAR IMAGING AND BIOLOGY
  • 2010-11 α-N-Heterocyclic thiosemicarbazones induce ER stress-mediated CHOP activation in BMC PHARMACOLOGY
  • 2010-08 Organometallic indolo[3,2-c]quinolines versus indolo[3,2-d]benzazepines: synthesis, structural and spectroscopic characterization, and biological efficacy in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2010-06 Ruthenium versus platinum: interactions of anticancer metallodrugs with duplex oligonucleotides characterised by electrospray ionisation mass spectrometry in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2010-06 Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339 in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2010-04 Albumin-based nanoparticles as magnetic resonance contrast agents: I. Concept, first syntheses and characterisation in HISTOCHEMISTRY AND CELL BIOLOGY
  • 2008-09 Synthesis and structural peculiarities of gallium Complexes with novel paullone derivatives in CENTRAL EUROPEAN JOURNAL OF CHEMISTRY
  • 2005-05 Synthesis, Cytotoxicity, and Structure-Activity Relationships of New Oxaliplatin Derivatives in MONATSHEFTE FÜR CHEMIE - CHEMICAL MONTHLY
  • 2005-03 Design, synthesis, physical and chemical characterisation, and biological interactions of lectin-targeted latex nanoparticles bearing Gd–DTPA chelates: an exploration of magnetic resonance molecular imaging (MRMI) in HISTOCHEMISTRY AND CELL BIOLOGY
  • 2005-02 On the Coordination Properties of New Bicyclophosphite-Carbohydrates in MONATSHEFTE FÜR CHEMIE - CHEMICAL MONTHLY
  • 2005-02 Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • 2005 Pharmacological properties of cerium compunds in REVIEWS OF PHYSIOLOGY, BIOCHEMISTRY AND PHARMACOLOGY
  • 2001-07 HPIC–UV–ICP–SFMS study of the interaction of cisplatin with guanosine monophosphate in JOURNAL OF ANALYTICAL CHEMISTRY
  • 2001-04 Biophysical analysis of natural, double-helical DNA modified by anticancer heterocyclic complexes of ruthenium(III) in cell-free media in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2001-03 Hydrolysis of the tumor-inhibiting ruthenium(III) complexes HIm trans-[RuCl4(im)2] and HInd trans-[RuCl4(ind)2] investigated by means of HPCE and HPLC-MS in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 2000-08 Time-dependent interactions of platinum(II) complexes with 5′-GMP under simulated physiological conditions studied by capillary electrophoresis in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 1999 Non-Platinum Antitumor Compounds in METALLOPHARMACEUTICALS I
  • 1997-08 Synthesis of water-soluble ruthenium porphyrins as DNA cleavers and potential cytotoxic agents in JBIC JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY
  • 1996 Overview of Tumor-Inhibiting Non-Platinum Compounds in PLATINUM AND OTHER METAL COORDINATION COMPOUNDS IN CANCER CHEMOTHERAPY 2
  • 1995-01 Antitumor platinum compounds linked to amino phosphonic acids with particular activity against bone malignancies in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
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