Mitch Dowsett


Ontology type: schema:Person     


Person Info

NAME

Mitch

SURNAME

Dowsett

Publications in SciGraph latest 50 shown

  • 2018-12 Novel 18-gene signature for predicting relapse in ER-positive, HER2-negative breast cancer in BREAST CANCER RESEARCH
  • 2018-12 Targeting tumour re-wiring by triple blockade of mTORC1, epidermal growth factor, and oestrogen receptor signalling pathways in endocrine-resistant breast cancer in BREAST CANCER RESEARCH
  • 2018-08-24 An international multicenter study to evaluate reproducibility of automated scoring for assessment of Ki67 in breast cancer in MODERN PATHOLOGY
  • 2018-08 Abiraterone shows alternate activity in models of endocrine resistant and sensitive disease in BRITISH JOURNAL OF CANCER
  • 2018-02 Discordance between oncotype DX recurrence score and RSPC for predicting residual risk of recurrence in ER-positive breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2017-12 Childhood body size and pubertal timing in relation to adult mammographic density phenotype in BREAST CANCER RESEARCH
  • 2017-12 Menstrual cycle characteristics and steroid hormone, prolactin, and growth factor levels in premenopausal women in CANCER CAUSES & CONTROL
  • 2017-12 Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance in NATURE COMMUNICATIONS
  • 2017-12 Molecular changes in premenopausal oestrogen receptor-positive primary breast cancer in Vietnamese women after oophorectomy in NPJ BREAST CANCER
  • 2017-12 Biomarker analysis of the NeoSphere study: pertuzumab, trastuzumab, and docetaxel versus trastuzumab plus docetaxel, pertuzumab plus trastuzumab, or pertuzumab plus docetaxel for the neoadjuvant treatment of HER2-positive breast cancer in BREAST CANCER RESEARCH
  • 2017-12 Gene expression modules in primary breast cancers as risk factors for organotropic patterns of first metastatic spread: a case control study in BREAST CANCER RESEARCH
  • 2016-12 Analytical validation of a standardized scoring protocol for Ki67: phase 3 of an international multicenter collaboration in NPJ BREAST CANCER
  • 2016-12 Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer in BREAST CANCER RESEARCH
  • 2016-12 Impact of type of full-field digital image on mammographic density assessment and breast cancer risk estimation: a case-control study in BREAST CANCER RESEARCH
  • 2016-12 Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups in BREAST CANCER RESEARCH
  • 2016-12 Heterogeneity in global gene expression profiles between biopsy specimens taken peri-surgically from primary ER-positive breast carcinomas in BREAST CANCER RESEARCH
  • 2016-08 Retrospective analysis of molecular scores for the prediction of distant recurrence according to baseline risk factors in BREAST CANCER RESEARCH AND TREATMENT
  • 2016-04 Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 in NATURE GENETICS
  • 2015-12 A poetic story: lessons learnt from the world's largest breast cancer window of opportunity study in TRIALS
  • 2015-12 Integrative analyses identify modulators of response to neoadjuvant aromatase inhibitors in patients with early breast cancer in BREAST CANCER RESEARCH
  • 2015-06 Progesterone receptor A predominance is a discriminator of benefit from endocrine therapy in the ATAC trial in BREAST CANCER RESEARCH AND TREATMENT
  • 2015-06 An international study to increase concordance in Ki67 scoring in MODERN PATHOLOGY
  • 2015-01 Erratum to: Differences in expression of proliferation-associated genes and RANKL across the menstrual cycle in estrogen receptor-positive primary breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2015-01 Reduced progesterone levels explain the reduced risk of breast cancer in obese premenopausal women: a new hypothesis in BREAST CANCER RESEARCH AND TREATMENT
  • 2014-11 Differences in expression of proliferation-associated genes and RANKL across the menstrual cycle in estrogen receptor-positive primary breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2014-11 The AURORA initiative for metastatic breast cancer in BRITISH JOURNAL OF CANCER
  • 2014-10 Digital mammographic density and breast cancer risk: a case–control study of six alternative density assessment methods in BREAST CANCER RESEARCH
  • 2014-10 Identification of chemokine receptors as potential modulators of endocrine resistance in oestrogen receptor–positive breast cancers in BREAST CANCER RESEARCH
  • 2014-06 Relationship of PIK3CA mutation and pathway activity with antiproliferative response to aromatase inhibition in BREAST CANCER RESEARCH
  • 2014-06 Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study in BREAST CANCER RESEARCH
  • 2014-06 Evaluation of FLT-PET-CT as an imaging biomarker of proliferation in primary breast cancer in BRITISH JOURNAL OF CANCER
  • 2014-04 Combined effects of endogenous sex hormone levels and mammographic density on postmenopausal breast cancer risk: results from the Breakthrough Generations Study in BRITISH JOURNAL OF CANCER
  • 2014-01 HER2 in situ hybridization in breast cancer: clinical implications of polysomy 17 and genetic heterogeneity in MODERN PATHOLOGY
  • 2013-07 Immunohistochemical BAG1 expression improves the estimation of residual risk by IHC4 in postmenopausal patients treated with anastrazole or tamoxifen: a TransATAC study in BREAST CANCER RESEARCH AND TREATMENT
  • 2013-04 Phosphorylation of AKT pathway proteins is not predictive of benefit of taxane therapy in early breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2013-02 Expression of key oestrogen-regulated genes differs substantially across the menstrual cycle in oestrogen receptor-positive primary breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2013-02 A dual-center randomized controlled double blind trial assessing the effect of acupuncture in reducing musculoskeletal symptoms in breast cancer patients taking aromatase inhibitors in BREAST CANCER RESEARCH AND TREATMENT
  • 2012-10 Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo in BREAST CANCER RESEARCH
  • 2012-07 Weight change associated with anastrozole and tamoxifen treatment in postmenopausal women with or at high risk of developing breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2012-07 Profiling of residual breast cancers after neoadjuvant chemotherapy identifies DUSP4 deficiency as a mechanism of drug resistance in NATURE MEDICINE
  • 2012-06 Polymorphisms of CYP19A1 and response to aromatase inhibitors in metastatic breast cancer patients in BREAST CANCER RESEARCH AND TREATMENT
  • 2012-06 Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer in BREAST CANCER RESEARCH
  • 2012-04 Effects of cyclin D1 gene amplification and protein expression on time to recurrence in postmenopausal breast cancer patients treated with anastrozole or tamoxifen: a TransATAC study in BREAST CANCER RESEARCH
  • 2012-04 ER and HER2 expression are positively correlated in HER2 non-overexpressing breast cancer in BREAST CANCER RESEARCH
  • 2012-01 Non-existence of caveolin-1 gene mutations in human breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2012-01 The role of caveolin-1 in human breast cancer in BREAST CANCER RESEARCH AND TREATMENT
  • 2011-12 Revisiting the technical validation of tumour biomarker assays: how to open a Pandora's box in BMC MEDICINE
  • 2011-07 Transient over-expression of estrogen receptor-α in breast cancer cells promotes cell survival and estrogen-independent growth in BREAST CANCER RESEARCH AND TREATMENT
  • 2010-12 Predictive and prognostic factors in BREAST CANCER RESEARCH
  • 2010-11 Synergistic activity of letrozole and sorafenib on breast cancer cells in BREAST CANCER RESEARCH AND TREATMENT
  • Affiliations

  • Institute of Cancer Research (current)
  • Western Infirmary
  • Novartis (Switzerland)
  • National Cancer Institute
  • University of Vienna
  • University of Oxford
  • Hospital Universitari Arnau de Vilanova
  • Emory University
  • Centre Jean Perrin
  • Queen Charlotte's and Chelsea Hospital
  • Westmead Hospital
  • Dana–Farber Cancer Institute
  • University of Newcastle Australia
  • The University of Texas Health Science Center at San Antonio
  • Croydon University Hospital
  • Royal Marsden NHS Foundation Trust
  • The University of Texas MD Anderson Cancer Center
  • Pfizer (United States)
  • Klinikum Kassel
  • University of North Carolina at Chapel Hill
  • Roche (Switzerland)
  • University Hospital Frankfurt
  • Tohoku University
  • Hospital Clínico Universitario Lozano Blesa
  • Duke University Hospital
  • Royal Victoria Infirmary
  • Breast Cancer Now
  • Queen Mary University of London
  • National and Kapodistrian University of Athens
  • Medical University of Vienna
  • Sunnybrook Health Science Centre
  • International Breast Cancer Study Group
  • Western General Hospital
  • University of California, San Francisco
  • William Beaumont Hospital
  • Tokai University
  • Baylor College of Medicine
  • Royal Bournemouth Hospital
  • Genomic Health (United States)
  • University of Virginia Health System
  • The Christie Hospital
  • Mayo Clinic
  • Antoni van Leeuwenhoek Hospital
  • Cancer Research UK
  • Royal Marsden Hospital
  • University of Michigan–Ann Arbor
  • Haukeland University Hospital
  • University of Michigan Health System
  • Calvary Mater Newcastle Hospital
  • European Institute of Oncology
  • National Health Service
  • Wythenshawe Hospital
  • Bradford Royal Infirmary
  • University College London
  • Institut Jules Bordet
  • Ospedale San Martino
  • Newcastle Hospitals - Campus for Ageing and Vitality
  • Washington University in St. Louis
  • Klinikum der Universität München
  • University of Milan
  • University of Edinburgh
  • AstraZeneca (United Kingdom)
  • Charité
  • JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

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