Stephen D Gillies

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Stephen D



Publications in SciGraph latest 50 shown

  • 2018-10 Pilot trial of the hu14.18-IL2 immunocytokine in patients with completely resectable recurrent stage III or stage IV melanoma in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2016-08 Enhanced binding of necrosis-targeting immunocytokine NHS-IL12 after local tumour irradiation in murine xenograft models in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2015-12 Immunocytokine augments local and abscopal response and animal survival when added to radiation and CTLA-4 checkpoint inhibition in a murine melanoma model in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2015-12 Activation of innate and adaptive immunity as an effective combined strategy for cancer immunotherapy in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2014-12 In vivo synergy of radiation and hu14.18-IL2 immunocytokine results in a memory T cell response in a syngeneic murine melanoma model in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2014-12 Evaluation of novel immunocytokines that preferentially target high or intermediate affinity IL-2 receptors in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2013-08 Intratumoral treatment of smaller mouse neuroblastoma tumors with a recombinant protein consisting of IL-2 linked to the Hu14.18 antibody increases intratumoral CD8+ T and NK cells and improves survival in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2013-04 Enhancement of the anti-melanoma response of Hu14.18K322A by αCD40 + CpG in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2012-12 Phase II trial of hu14.18-IL2 for patients with metastatic melanoma in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2011-12 Ab-IL2 fusion proteins mediate NK cell immune synapse formation by polarizing CD25 to the target cell-effector cell interface in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2011-05 The anti-tumor effect of resveratrol alone or in combination with immunotherapy in a neuroblastoma model in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2009-12 Phase I/II open-label study of the biologic effects of the interleukin-2 immunocytokine EMD 273063 (hu14.18-IL2) in patients with metastatic malignant melanoma in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2008-12 Intratumoral immunocytokine treatment results in enhanced antitumor effects in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2007-11 Flt3-L gene therapy enhances immunocytokine-mediated antitumor effects and induces long-term memory in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2007-04 huBC1-IL12, an immunocytokine which targets EDB-containing oncofetal fibronectin in tumors and tumor vasculature, shows potent anti-tumor activity in human tumor models in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2007 Novel Strategies for Cytokine Administration Via Targetting in CYTOKINES IN THE GENESIS AND TREATMENT OF CANCER
  • 2006-06 Endostatin therapy reveals a U-shaped curve for antitumor activity in CANCER GENE THERAPY
  • 2004-01 NXS2 murine neuroblastomas express increased levels of MHC class I antigens upon recurrence following NK-dependent immunotherapy in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2003-03-26 Determination of Peak Serum Levels and Immune Response to the Humanized Anti-Ganglioside Antibody-Interleukin-2 Immunocytokine in NOVEL ANTICANCER DRUG PROTOCOLS
  • 2002-10 Bi-functional cytokine fusion proteins for gene therapy and antibody-targeted treatment of cancer in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 1999-08 Pharmacokinetics and stability of the ch14.18–interleukin-2 fusion protein in mice in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 1997-04 FP-21399 blocks HIV envelope protein-mediated membrane fusion and concentrates in lymph nodes in NATURE BIOTECHNOLOGY
  • 1996-03 Eradication of established hepatic human neuroblastoma metastases in mice with severe combined immunodeficiency by antibody-targeted interleukin-2 in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 1994-05 Mapping effector functions of a monoclonal antibody to GD3 by characterization of a mouse-human chimeric antibody in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 1993-09 Therapeutic potential of chimeric and murine anti-(epidermal growth factor receptor) antibodies in a metastasis model for human melanoma in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 1992-09 Distinct and overlapping functions of allelic forms of human mannose binding protein in NATURE GENETICS
  • 1989-08 Expression of Human Anti-Tetanus Toxoid Antibody in Transfected Murine Myeloma Cells in NATURE BIOTECHNOLOGY
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