E Premkumar Reddy

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E Premkumar



Publications in SciGraph latest 50 shown

  • 2017-06-23 Drugging the 'undruggable' cancer targets in NATURE REVIEWS CANCER
  • 2016-01 Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas in LEUKEMIA
  • 2013-01 Integrated Pharmacokinetic-Driven Approach to Screen Candidate Anticancer Drugs for Brain Tumor Chemotherapy in THE AAPS JOURNAL
  • 2013 Mechanisms of Resistance to Targeted B-Raf Therapies in MOLECULAR MECHANISMS OF TUMOR CELL RESISTANCE TO CHEMOTHERAPY
  • 2012-12 Screening candidate anticancer drugs for brain tumor chemotherapy: Pharmacokinetic-driven approach for a series of (E)-N-(substituted aryl)-3-(substituted phenyl)propenamide analogues in INVESTIGATIONAL NEW DRUGS
  • 2012-09 Preclinical Pharmacokinetic and Pharmacodynamic Evaluation of Novel Anticancer Agents, ON01910.Na (Rigosertib, Estybon™) and ON013105, for Brain Tumor Chemotherapy in PHARMACEUTICAL RESEARCH
  • 2009-10 New therapeutics targeting colon cancer stem cells in CURRENT COLORECTAL CANCER REPORTS
  • 2009-09-22 Mitogen-Activated Protein Kinases and Their Scaffolding Proteins in SIGNAL TRANSDUCTION: PATHWAYS, MECHANISMS AND DISEASES
  • 2009-03 Styryl sulfonyl compounds inhibit translation of cyclin D1 in mantle cell lymphoma cells in ONCOGENE
  • 2009 Mechanisms of Resistance to Targeted Tyrosine Kinase Inhibitors in DRUG RESISTANCE IN CANCER CELLS
  • 2009-01 Evaluation of the novel mitotic modulator ON 01910.Na in pancreatic cancer and preclinical development of an ex vivo predictive assay in ONCOGENE
  • 2008-10 JNK signaling in apoptosis in ONCOGENE
  • 2008-04 Celecoxib and a novel COX-2 inhibitor ON09310 upregulate death receptor 5 expression via GADD153/CHOP in ONCOGENE
  • 2007-11 Disruption of transforming growth factor-β signaling through β-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation in ONCOGENE
  • 2007-10 Hematopoietic cytokine receptor signaling in ONCOGENE
  • 2007-08 Evaluation of novel cell cycle inhibitors in mantle cell lymphoma in ONCOGENE
  • 2007-05 Scaffold proteins of MAP-kinase modules in ONCOGENE
  • 2006-04 Granulocyte colony-stimulating factor-induced upregulation of Jak3 transcription during granulocytic differentiation is mediated by the cooperative action of Sp1 and Stat3 in ONCOGENE
  • 2006-03 Critical interactions between TGF-β signaling/ELF, and E-cadherin/β-catenin mediated tumor suppression in ONCOGENE
  • 2005-12 Inactivation of ELF/TGF-β signaling in human gastrointestinal cancer in ONCOGENE
  • 2002-12 Transforming pathways activated by the v-Abl tyrosine kinase in ONCOGENE
  • 2002-05 JAKs, STATs and Src kinases in hematopoiesis in ONCOGENE
  • 2001-03 Characterization of an alternatively spliced AATYK mRNA: Expression pattern of AATYK in the brain and neuronal cells in ONCOGENE
  • 2000-11 Janus kinases: components of multiple signaling pathways in ONCOGENE
  • 2000-05 IL-3 signaling and the role of Src kinases, JAKs and STATs: a covert liaison unveiled in ONCOGENE
  • 1999-12 Oncogenic mutant of Gα12 stimulates cell proliferation through cycloxygenase-2 signaling pathway in ONCOGENE
  • 1999-05 Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia in NATURE GENETICS
  • 1999-05 The myb gene family in cell growth, differentiation and apoptosis in ONCOGENE
  • 1999-05 The v-myc oncogene in ONCOGENE
  • 1998-12 Modulation of life and death by the TNF receptor superfamily in ONCOGENE
  • 1998-09 Signaling by dual specificity kinases in ONCOGENE
  • 1998-06-23 Folate-Polylysine-Mediated Delivery of a Multiunit Anti-BCRIABL Ribozyme to BCR/ABL-Transformed 32D Cells in THERAPEUTIC APPLICATIONS OF RIBOZYMES
  • 1998-04 Src kinases and not JAKs activate STATs during IL-3 induced myeloid cell proliferation in ONCOGENE
  • 1997-12 AATYK: A novel tyrosine kinase induced during growth arrest and apoptosis of myeloid cells in ONCOGENE
  • 1997-10 cAMP-induced NF-κB (p50/relB) binding to a c-myb intronic enhancer correlates with c-myb up-regulation and inhibition of erythroleukemia cell differentiation in ONCOGENE
  • 1997-04 Arrest of spermatogenesis and defective breast development in mice lacking A-myb in NATURE
  • 1995-06 Scintigraphic imaging of oncogenes with antisense probes: does it make sense? in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 1987 Mechanisms in Interleukin 3 Regulated Growth and Differentiation in MECHANISMS OF LYMPHOCYTE ACTIVATION AND IMMUNE REGULATION
  • 1986-02 Nucleotide sequence of chicken c-myb complementary DNA and implications for myb oncogene activation in NATURE
  • 1984 Structural Organization of Mouse c-myb Locus and the Mechanism of its Rearrangement in ABPL-2 Tumor Line Induced by Pristane and Abelson Murine Leukemia Virus in ONCOGENES IN B-CELL NEOPLASIA
  • 1984 Disruption and Activation of the c-myb Locus by M-MuLV Insertion in Plasmacytoid Lymphosarcomas Induced by Pristane and Abelson Viruses in ONCOGENES IN B-CELL NEOPLASIA
  • 1983-06 Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene in NATURE
  • 1983 The Transforming Gene of Avian Myeloblastosis Virus (AMV): Nucleotide Sequence Analysis and Identification of Its Translational Product in MODERN TRENDS IN HUMAN LEUKEMIA V
  • 1983 Nucleotide Sequence Analysis of Integrated Avian Myeloblastosis Virus (AMV) Long Terminal Repeat (LTR) and Their Host and Viral Junctions: Structural Similarities to Transposable Elements in BIOCHEMICAL AND BIOLOGICAL MARKERS OF NEOPLASTIC TRANSFORMATION
  • 1982-11 A cDNA sequence encoding a rabbit heavy chain variable region of the VHa2 allotype showing homologies with human heavy chain sequences in NATURE
  • 1982-11 A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene in NATURE
  • 1982-01 Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells in NATURE
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