Thomas H Bugge


Ontology type: schema:Person     


Person Info

NAME

Thomas H

SURNAME

Bugge

Publications in SciGraph latest 50 shown

  • 2017-12 Matriptase zymogen supports epithelial development, homeostasis and regeneration in BMC BIOLOGY
  • 2015-12 An anthrax toxin variant with an improved activity in tumor targeting in SCIENTIFIC REPORTS
  • 2015-08 Matriptase promotes inflammatory cell accumulation and progression of established epidermal tumors in ONCOGENE
  • 2015-01 Non-hematopoietic PAR-2 is essential for matriptase-driven pre-malignant progression and potentiation of ras-mediated squamous cell carcinogenesis in ONCOGENE
  • 2012-08 Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis in ONCOGENE
  • 2011-04 c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase in ONCOGENE
  • 2011-03-19 Cooperation Between Proteolysis and Endocytosis in Collagen Turnover in EXTRACELLULAR MATRIX DEGRADATION
  • 2010-08 Matriptase initiates activation of epidermal pro-kallikrein and disease onset in a mouse model of Netherton syndrome in NATURE GENETICS
  • 2009-10 Matriptase-Deficient Mice Exhibit Ichthyotic Skin with a Selective Shift in Skin Microbiota in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2009 Dissecting the Urokinase Activation Pathway Using Urokinase-Activated Anthrax Toxin in PROTEASES AND CANCER
  • 2009 Imaging Specific Cell Surface Protease Activity in Living Cells Using Reengineered Bacterial Cytotoxins in PROTEASES AND CANCER
  • 2008-08 Profibrinolytic Effects of Metalloproteinases during Skin Wound Healing in the Absence of Plasminogen in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2008 Physiological Functions of Plasminogen Activation: Effects of Gene Deficiencies in Humans and Mice in THE CANCER DEGRADOME
  • 2008 Physiological and Pathological Functions of Type II Transmembrane Serine Proteases: Lessons from Transgenic Mouse Models and Human Disease-Associated Mutations in THE CANCER DEGRADOME
  • 2007-03 Matriptase inhibition by hepatocyte growth factor activator inhibitor-1 is essential for placental development in ONCOGENE
  • 2006-04 Imaging specific cell-surface proteolytic activity in single living cells in NATURE METHODS
  • 2006-02 Anthrax target in macrophages unveiled in NATURE GENETICS
  • 2006-01 Matriptase: Potent Proteolysis on the Cell Surface in MOLECULAR MEDICINE
  • 2005-06 Intermolecular complementation achieves high-specificity tumor targeting by anthrax toxin in NATURE BIOTECHNOLOGY
  • 2003-06 Laser capture microdissection-based in vivo genomic profiling of wound keratinocytes identifies similarities and differences to squamous cell carcinoma in ONCOGENE
  • 2003-06 Membrane anchored serine proteases: A rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer in CANCER AND METASTASIS REVIEWS
  • 2002-12 Plasminogen promotes sarcoma growth and suppresses the accumulation of tumor-infiltrating macrophages in ONCOGENE
  • 2002-05 Matriptase/MT-SP1 is required for postnatal survival, epidermal barrier function, hair follicle development, and thymic homeostasis in ONCOGENE
  • 2001-10 The Urokinase Plasminogen Activator Receptor–Associated Protein/Endo180 Is Coexpressed with Its Interaction Partners Urokinase Plasminogen Activator Receptor and Matrix Metalloprotease-13 during Osteogenesis in LABORATORY INVESTIGATION
  • 2001-04 Profiling changes in keratinocyte gene expression during wound reepithelialization by laser capture microdissection combined with cDNA array analysis in NATURE GENETICS
  • 1998-06 Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice in ONCOGENE
  • 1996-07 Plasminogen and wound healing in NATURE MEDICINE
  • 1996-03 Impaired wound healing in mice with a disrupted plasminogen gene in NATURE MEDICINE
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