Jerry M Adams

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Jerry M



Publications in SciGraph latest 50 shown

  • 2021-06-16 BAX mitochondrial integration is regulated allosterically by its α1−α2 loop in CELL DEATH & DIFFERENTIATION
  • 2020-04-23 Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target in CELL DEATH & DISEASE
  • 2019-11-26 Potent efficacy of MCL-1 inhibitor-based therapies in preclinical models of mantle cell lymphoma in ONCOGENE
  • 2019-11-15 BAX and BAK become killers without a BH3 trigger in CELL RESEARCH
  • 2018-12-11 By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737 in CELL DEATH & DIFFERENTIATION
  • 2017-11-03 The BCL-2 arbiters of apoptosis and their growing role as cancer targets in CELL DEATH & DIFFERENTIATION
  • 2016-03-10 Critical B-lymphoid cell intrinsic role of endogenous MCL-1 in c-MYC-induced lymphomagenesis in CELL DEATH & DISEASE
  • 2014-05-26 Functional antagonism between pro-apoptotic BIM and anti-apoptotic BCL-XL in MYC-induced lymphomagenesis in ONCOGENE
  • 2013-12-20 Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2013-04-21 Structure-guided design of a selective BCL-XL inhibitor in NATURE CHEMICAL BIOLOGY
  • 2012-07-20 Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice in CELL DEATH & DIFFERENTIATION
  • 2011-09-12 Can the analysis of BH3-only protein knockout mice clarify the issue of ‘direct versus indirect’ activation of Bax and Bak? in CELL DEATH & DIFFERENTIATION
  • 2010-04-30 Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development in CELL DEATH & DIFFERENTIATION
  • 2009-11-13 Apoptosis and non-inflammatory phagocytosis can be induced by mitochondrial damage without caspases in CELL DEATH & DIFFERENTIATION
  • 2009-01-16 Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis in CELL DEATH & DIFFERENTIATION
  • 2008-02-08 In several cell types tumour suppressor p53 induces apoptosis largely via Puma but Noxa can contribute in CELL DEATH & DIFFERENTIATION
  • 2007-02-26 The Bcl-2 apoptotic switch in cancer development and therapy in ONCOGENE
  • 2004-04-11 Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate in NATURE CELL BIOLOGY
  • 2003-11-24 The Bcl-2 family: roles in cell survival and oncogenesis in ONCOGENE
  • 2003-09-12 Role of BH3-only protein Bim in autoimmune and degenerative diseases in ARTHRITIS RESEARCH & THERAPY
  • 2003-02 Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region in CELL DEATH & DIFFERENTIATION
  • 2002-10-29 Pro-apoptotic BH3-only Bcl-2 family members in vertebrate model organisms suitable for genetic experimentation in CELL DEATH & DIFFERENTIATION
  • 2002-09-25 Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome in NATURE
  • 2002-09-01 The Bcl2 family: regulators of the cellular life-or-death switch in NATURE REVIEWS CANCER
  • 2002-07 Correction: Corrigenda: BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes in NATURE
  • 2002-02 BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes in NATURE
  • 2001-02 Gene structure, alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim in MAMMALIAN GENOME
  • 2000-08-08 Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine in ONCOGENE
  • 1999-11-13 Interference with gene expression induces rapid apoptosis in p53-null T lymphoma cells in CELL DEATH & DIFFERENTIATION
  • 1999-09-20 Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector in ONCOGENE
  • 1999-06-07 Survival activity of Bcl-2 homologs Bcl-w and A1 only partially correlates with their ability to bind pro-apoptotic family members in CELL DEATH & DIFFERENTIATION
  • 1995 Cyclin D1 as the Putative bcl-1 Oncogene in MECHANISMS IN B-CELL NEOPLASIA 1994
  • 1995 Contribution of the Cyclin D1 Gene to Lymphomagenesis in NORMAL AND MALIGNANT HEMATOPOIESIS
  • 1993-01 Nucleotide sequence ofbup, an upstream gene in thebmi-1 proviral insertion locus in MOLECULAR BIOLOGY REPORTS
  • 1990 Abnormalities of the Immune System Induced by Dysregulated bcl-2 Expression in Transgenic Mice in MECHANISMS IN B-CELL NEOPLASIA 1990
  • 1990 Lymphoid Tumorigenesis by v-abl and BCR-v-abl in Transgenic Mice in MECHANISMS IN B-CELL NEOPLASIA 1990
  • 1989 Transgenic Mice as Models for the Development of Haemopoietic Neoplasia in PROGRESS IN IMMUNOLOGY
  • 1989 Analysis of the Leukemogenic Properties of the bcr-v-abl and GM-CSF Genes Using a New Retroviral Vector in MECHANISMS IN MYELOID TUMORIGENESIS 1988
  • 1989 Oncogene Cooperation and B-Lymphoid Tumorigenesis in Eµ-myc Transgenic Mice in MODERN TRENDS IN HUMAN LEUKEMIA VIII
  • 1988-10 Immunoglobulin JH rearrangement in a T-cell line reflects fusion to the DH locus at a sequence lacking the nonamer recognition signal in IMMUNOGENETICS
  • 1988-09 Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells in NATURE
  • 1988 Transgenic Mouse Models for Hematopoietic Tumorigenesis in MECHANISMS IN B-CELL NEOPLASIA 1988
  • 1987 The myc Oncogene and Lymphoid Neoplasia: From Translocations to Transgenic Mice in MODERN TRENDS IN HUMAN LEUKEMIA VII
  • 1986 c-Myc-Induced Lymphomagenesis in Transgenic Mice and the Role of the Pvt-1 Locus in Lymphoid Neoplasia in MECHANISMS IN B-CELL NEOPLASIA
  • 1985-12-01 The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice in NATURE
  • 1985-06 Oncogenic intelligence: Oncogene activation by fusion of chromosomes in leukaemia in NATURE
  • 1985-04 Murine T lymphomas with retroviral inserts in the chromosomal 15 locus for plasmacytoma variant translocations in NATURE
  • 1984-12 Variant (6 ; 15) translocation in a murine plasmacytoma occurs near an immunoglobulin κ gene but far from the myc oncogene in NATURE
  • 1984 Activation of the c-myc Oncogene in B and T Lymphoid Tumors in ONCOGENES IN B-CELL NEOPLASIA
  • 1981-10 Generation of long mRNA for membrane immunoglobulin γ2a chains by differential splicing in NATURE
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