James P Allison

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James P



Publications in SciGraph latest 50 shown

  • 2018-11-27 Author Correction: Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis in NATURE MEDICINE
  • 2018-11-12 Fecal microbiota transplantation for refractory immune checkpoint inhibitor-associated colitis in NATURE MEDICINE
  • 2018-05 Hypomethylating agents in combination with immune checkpoint inhibitors in acute myeloid leukemia and myelodysplastic syndromes in LEUKEMIA
  • 2017-12 Genomic and immune heterogeneity are associated with differential responses to therapy in melanoma in NPJ GENOMIC MEDICINE
  • 2017-12 Phase I clinical trial of combination imatinib and ipilimumab in patients with advanced malignancies in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2017-12 HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes in NATURE COMMUNICATIONS
  • 2017-05 VISTA is an inhibitory immune checkpoint that is increased after ipilimumab therapy in patients with prostate cancer in NATURE MEDICINE
  • 2017-04-27 Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer in NATURE COMMUNICATIONS
  • 2017-02-13 Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity in NATURE COMMUNICATIONS
  • 2016-12 Selective inhibition of autoimmune exacerbation while preserving the anti-tumor clinical benefit using IL-6 blockade in a patient with advanced melanoma and Crohn’s disease: a case report in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2016-08-30 Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity in NATURE COMMUNICATIONS
  • 2016-08-08 Interdependent IL-7 and IFN-γ signalling in T-cell controls tumour eradication by combined α-CTLA-4+α-PD-1 therapy in NATURE COMMUNICATIONS
  • 2015-12 Immune correlates in a Phase II clinical trial with ipilimumab in combination with finite androgen deprivation therapy in patients with metastatic non-castrate prostate cancer in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2015-12 Pilot study of intratumoral (IT) cryoablation (cryo) in combination with systemic checkpoint blockade in patients with metastatic melanoma (MM) in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2015-09 Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis in NATURE MEDICINE
  • 2015-03 Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25 in CELL RESEARCH
  • 2015-02 Anticancer immunotherapy by CTLA-4 blockade: obligatory contribution of IL-2 receptors and negative prognostic impact of soluble CD25 in CELL RESEARCH
  • 2014-12 Potentiation of immunomodulatory antibodies with oncolytic viruses for therapy of poorly-immunogenic tumors in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2014-11 Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens in NATURE
  • 2014-04 Vaccination with tumor cells expressing IL-15 and IL-15Rα inhibits murine breast and prostate cancer in GENE THERAPY
  • 2013-11 Indoleamine 2,3-dioxygenase is a critical resistance mechanism in anti-tumor T cell immunotherapy targeting CTLA-4 in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2013-11 Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2013-09 Immunological Insights from Patients Undergoing Surgery on Ipilimumab for Metastatic Melanoma in ANNALS OF SURGICAL ONCOLOGY
  • 2013 Immune Co-signaling to Treat Cancer in CANCER IMMUNOTHERAPY
  • 2012-12 Cancer classification using the Immunoscore: a worldwide task force in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2012-10 Gene Therapy-Mediated Reprogramming Tumor Infiltrating T Cells Using IL-2 and Inhibiting NF-κB Signaling Improves the Efficacy of Immunotherapy in a Brain Cancer Model in NEUROTHERAPEUTICS
  • 2012-02 Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting in NATURE
  • 2011-12 Defining the critical hurdles in cancer immunotherapy in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2011-11 Novel cancer immunotherapy agents with survival benefit: recent successes and next steps in NATURE REVIEWS CANCER
  • 2011-11 Nobels: Toll pioneers deserve recognition in NATURE
  • 2011-09 Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido in NATURE MEDICINE
  • 2011-08 CTLA-4 blockade increases antigen-specific CD8+ T cells in prevaccinated patients with melanoma: three cases in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2010-08 Tumor associated endothelial expression of B7-H3 predicts survival in ovarian carcinomas in MODERN PATHOLOGY
  • 2008-08 Local secretion of anti-CTLA-4 enhances the therapeutic efficacy of a cancer immunotherapy with reduced evidence of systemic autoimmunity in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2007 Checkpoint Blockade and Combinatorial Immunotherapies in GENERAL PRINCIPLES OF TUMOR IMMUNOTHERAPY
  • 2006-02 Restoring function in exhausted CD8 T cells during chronic viral infection in NATURE
  • 2005-12 Breaking down the barriers to cancer immunotherapy in NATURE IMMUNOLOGY
  • 2004-11 Translation of cancer immunotherapies in NATURE MEDICINE
  • 2004-11 Translation of cancer immunotherapies in NATURE MEDICINE
  • 2004-09 Cancer immunotherapy: breaking the barriers to harvest the crop in NATURE MEDICINE
  • 2004-09 Emerging mechanisms of immune regulation: the extended B7 family and regulatory T cells in ARTHRITIS RESEARCH & THERAPY
  • 2003-07 BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1 in NATURE IMMUNOLOGY
  • 2003-03 Prostate Cancer in BIODRUGS
  • 2002-07 CTLA-4: new insights into its biological function and use in tumor immunotherapy in NATURE IMMUNOLOGY
  • 1998 Manipulation of T Cell Activation in the Anti-Tumor Immune Response in THE BIOLOGY OF TUMORS
  • 1992-04 CD28-mediated signalling co-stimulates murine T cells and prevents induction of anergy in T-cell clones in NATURE
  • 1991 γδ T Cells in Murine Epithelia: Origin, Repertoire, and Function in MECHANISMS OF LYMPHOCYTE ACTIVATION AND IMMUNE REGULATION III
  • 1990-03 Origin of Thy-1+ dendritic epidermal cells of adult mice from fetal thymic precursors in NATURE
  • 1989-09 Distinct antigen receptor repertoires of two classes of murine epithelium-associated T cells in NATURE
  • 1988-12 γδ Antigen receptors of Thy-1 + dendritic epidermal cells: Implications for thymic differentiation in IMMUNOLOGIC RESEARCH
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