Jan Cools

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Publications in SciGraph latest 50 shown

  • 2019-02 The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL in LEUKEMIA
  • 2018-12 The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2018-09-19 Correction: Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2018-06 Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2018-04 Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T-cell model system in LEUKEMIA
  • 2018-03 The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling in LEUKEMIA
  • 2018-03 Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2016-09 Generation of the Fip1l1–Pdgfra fusion gene using CRISPR/Cas genome editing in LEUKEMIA
  • 2015-12 Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2015-12 JAK kinase inhibitors for the treatment of acute lymphoblastic leukemia in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2015-11 The genomic landscape of adult T cell leukemia/lymphoma in NATURE GENETICS
  • 2015-09 A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2) in SCIENTIFIC REPORTS
  • 2014-04 RHOA mutations in peripheral T cell lymphoma in NATURE GENETICS
  • 2013-07 Cancer: Mutations close in on gene regulation in NATURE
  • 2013-02 Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia in NATURE GENETICS
  • 2012-07 Ponatinib is active against imatinib-resistant mutants of FIP1L1-PDGFRA and KIT, and against FGFR1-derived fusion kinases in LEUKEMIA
  • 2012-01 The genetic basis of early T-cell precursor acute lymphoblastic leukaemia in NATURE
  • 2011-01 PHF6 mutations in adult acute myeloid leukemia in LEUKEMIA
  • 2010-06 Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia in NATURE GENETICS
  • 2009-05 FIP1L1-PDGFRα D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRα T674I eosinophilic leukemia with single agent sorafenib in LEUKEMIA
  • 2009-01 Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2008-12 Intrinsic differences between the catalytic properties of the oncogenic NUP214-ABL1 and BCR-ABL1 fusion protein kinases in LEUKEMIA
  • 2008-11 Five years since the discovery of FIP1L1–PDGFRA: what we have learned about the fusion and other molecularly defined eosinophilias in LEUKEMIA
  • 2008-06 Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies in LEUKEMIA
  • 2007-09 Interstitial del(14)(q) involving IGH: a novel recurrent aberration in B-NHL in LEUKEMIA
  • 2007-09 Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1–like phenotype in NATURE GENETICS
  • 2007-05 Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia in NATURE GENETICS
  • 2007-04 A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome in LEUKEMIA
  • 2007-03 FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells in LEUKEMIA
  • 2007-01 Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRβ-HOXA rearrangement: a study of the Groupe Francophone de Cytogénétique Hématologique in LEUKEMIA
  • 2007 Hypereosinophilic Syndrome in MYELOPROLIFERATIVE DISORDERS
  • 2006-12 Transition from EML1-ABL1 to NUP214-ABL1 positivity in a patient with acute T-lymphoblastic leukemia in LEUKEMIA
  • 2006-09 Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast in LEUKEMIA
  • 2006-07 Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCRβ locus rearrangements and putative new T-cell oncogenes in LEUKEMIA
  • 2006-02 Chronic myeloproliferative disorders: a tyrosine kinase tale in LEUKEMIA
  • 2006-02 Cryptic chromosomal aberrations waiting to be discovered in LEUKEMIA
  • 2005-11-15 Detection of the <I>FIP1L1-PDGFRA</I> Fusion in Idiopathic Hypereosinophilic Syndrome and Chronic Eosinophilic Leukemia in MYELOID LEUKEMIA
  • 2005-03 A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias in LEUKEMIA
  • 2005-02 e6-a2 BCR-ABL1 fusion in T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2005-01 KIAA1509 is a novel PDGFRB fusion partner in imatinib-responsive myeloproliferative disease associated with a t(5;14)(q33;q32) in LEUKEMIA
  • 2004-10 Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia in NATURE GENETICS
  • 2004-04 Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias in LEUKEMIA
  • 2004 FIP1L1-PDGFRalpha in hypereosinophilic syndrome and mastocytosis. in HAEMATOLOGICA
  • 2002-09 The novel t(11;12;18)(q21;q13;q21) represents a variant translocation of the t(11;18)(q21;q21) associated with MALT-type lymphoma in LEUKEMIA
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