Jan Cools

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Publications in SciGraph latest 50 shown

  • 2021-07-06 Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia in NATURE COMMUNICATIONS
  • 2021-06-24 PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2021-06-17 Fusion transcripts FYN-TRAF3IP2 and KHDRBS1-LCK hijack T cell receptor signaling in peripheral T-cell lymphoma, not otherwise specified in NATURE COMMUNICATIONS
  • 2021-05-18 MAPK-ERK is a central pathway in T-cell acute lymphoblastic leukemia that drives steroid resistance in LEUKEMIA
  • 2019-06-11 Translatome analysis reveals altered serine and glycine metabolism in T-cell acute lymphoblastic leukemia cells in NATURE COMMUNICATIONS
  • 2019-03-08 Correction: The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL in LEUKEMIA
  • 2018-09-19 Correction: Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2018-08-25 The CCR4-NOT complex is a tumor suppressor in Drosophila melanogaster eye cancer models in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2018-06-21 The ribosomal RPL10 R98S mutation drives IRES-dependent BCL-2 translation in T-ALL in LEUKEMIA
  • 2018-04-18 Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2017-11-20 Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T-cell model system in LEUKEMIA
  • 2017-08-30 Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2017-07-24 The T-cell leukemia associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling in LEUKEMIA
  • 2016-03-08 Generation of the Fip1l1–Pdgfra fusion gene using CRISPR/Cas genome editing in LEUKEMIA
  • 2015-10-28 The genomic landscape of adult T cell leukemia/lymphoma in NATURE GENETICS
  • 2015-07-26 JAK kinase inhibitors for the treatment of acute lymphoblastic leukemia in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2015-06-25 Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2015-06-04 A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2) in SCIENTIFIC REPORTS
  • 2014-03-27 RHOA mutations in peripheral T cell lymphoma in NATURE GENETICS
  • 2013-07-03 Mutations close in on gene regulation in NATURE
  • 2012-12-23 Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia in NATURE GENETICS
  • 2012-01-17 Ponatinib is active against imatinib-resistant mutants of FIP1L1-PDGFRA and KIT, and against FGFR1-derived fusion kinases in LEUKEMIA
  • 2012-01-11 The genetic basis of early T-cell precursor acute lymphoblastic leukaemia in NATURE
  • 2010-10-29 PHF6 mutations in adult acute myeloid leukemia in LEUKEMIA
  • 2010-05-16 Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia in NATURE GENETICS
  • 2009-02-12 FIP1L1-PDGFRα D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRα T674I eosinophilic leukemia with single agent sorafenib in LEUKEMIA
  • 2008-10-16 Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2008-10-09 Five years since the discovery of FIP1L1–PDGFRA: what we have learned about the fusion and other molecularly defined eosinophilias in LEUKEMIA
  • 2008-09-11 Intrinsic differences between the catalytic properties of the oncogenic NUP214-ABL1 and BCR-ABL1 fusion protein kinases in LEUKEMIA
  • 2008-04-10 Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies in LEUKEMIA
  • 2007-08-19 Germline loss-of-function mutations in SPRED1 cause a neurofibromatosis 1–like phenotype in NATURE GENETICS
  • 2007-05-24 Interstitial del(14)(q) involving IGH: a novel recurrent aberration in B-NHL in LEUKEMIA
  • 2007-04-15 Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia in NATURE GENETICS
  • 2007-02-15 A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome in LEUKEMIA
  • 2007-01-11 FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells in LEUKEMIA
  • 2007-01-01 Hypereosinophilic Syndrome in MYELOPROLIFERATIVE DISORDERS
  • 2006-10-12 Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRβ-HOXA rearrangement: a study of the Groupe Francophone de Cytogénétique Hématologique in LEUKEMIA
  • 2006-10-05 Transition from EML1-ABL1 to NUP214-ABL1 positivity in a patient with acute T-lymphoblastic leukemia in LEUKEMIA
  • 2006-07-06 Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast in LEUKEMIA
  • 2006-05-04 Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCRβ locus rearrangements and putative new T-cell oncogenes in LEUKEMIA
  • 2005-12-15 Cryptic chromosomal aberrations waiting to be discovered in LEUKEMIA
  • 2005-12-08 Chronic myeloproliferative disorders: a tyrosine kinase tale in LEUKEMIA
  • 2005-11-15 Detection of the FIP1L1-PDGFRA Fusion in Idiopathic Hypereosinophilic Syndrome and Chronic Eosinophilic Leukemia in MYELOID LEUKEMIA
  • 2005-01-27 A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias in LEUKEMIA
  • 2004-11-25 e6-a2 BCR-ABL1 fusion in T-cell acute lymphoblastic leukemia in LEUKEMIA
  • 2004-10-21 KIAA1509 is a novel PDGFRB fusion partner in imatinib-responsive myeloproliferative disease associated with a t(5;14)(q33;q32) in LEUKEMIA
  • 2004-09-12 Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia in NATURE GENETICS
  • 2004-02-19 Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias in LEUKEMIA
  • 2004 FIP1L1-PDGFRalpha in hypereosinophilic syndrome and mastocytosis. in HAEMATOLOGICA
  • 2002-08-30 The novel t(11;12;18)(q21;q13;q21) represents a variant translocation of the t(11;18)(q21;q21) associated with MALT-type lymphoma in LEUKEMIA
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