Frank Sicheri

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Publications in SciGraph latest 50 shown

  • 2021-12-14 Remembering a pioneer in biotechnology in NATURE
  • 2021-03-26 Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry in NATURE COMMUNICATIONS
  • 2020-12-04 A substrate binding model for the KEOPS tRNA modifying complex in NATURE COMMUNICATIONS
  • 2020-08-10 Functional characterization of a PROTAC directed against BRAF mutant V600E in NATURE CHEMICAL BIOLOGY
  • 2019-03-11 The ubiquitin interacting motifs of USP37 act on the proximal Ub of a di-Ub chain to enhance catalytic efficiency in SCIENTIFIC REPORTS
  • 2018-11-14 Author Correction: Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome in NATURE GENETICS
  • 2018-10-29 Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome in NATURE GENETICS
  • 2018-10-22 Monoubiquitination of ASXLs controls the deubiquitinase activity of the tumor suppressor BAP1 in NATURE COMMUNICATIONS
  • 2018-08-29 A feed forward loop enforces YAP/TAZ signaling during tumorigenesis in NATURE COMMUNICATIONS
  • 2018-08-27 Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase in NATURE MEDICINE
  • 2018-08-10 Real-time tracking of complex ubiquitination cascades using a fluorescent confocal on-bead assay in BMC BIOLOGY
  • 2018-02-12 MEK drives BRAF activation through allosteric control of KSR proteins in NATURE
  • 2017-12-06 Vivid views of the PINK1 protein in NATURE
  • 2017-11-27 Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR–Cas9 genome-editing efficiency in NATURE BIOTECHNOLOGY
  • 2017-01-03 An allosteric conduit facilitates dynamic multisite substrate recognition by the SCFCdc4 ubiquitin ligase in NATURE COMMUNICATIONS
  • 2016-11-07 Inhibition of RAS function through targeting an allosteric regulatory site in NATURE CHEMICAL BIOLOGY
  • 2016-07-27 The structural basis of modified nucleosome recognition by 53BP1 in NATURE
  • 2014-12-01 Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2014-08-28 Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors in NATURE COMMUNICATIONS
  • 2013-12-15 E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin in NATURE CHEMICAL BIOLOGY
  • 2013-06-12 53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark in NATURE
  • 2013-05-24 The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis in NATURE
  • 2013-05-19 Inhibitors that stabilize a closed RAF kinase domain conformation induce dimerization in NATURE CHEMICAL BIOLOGY
  • 2010-09-06 Mechanistic principles of RAF kinase signaling in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2010-08 Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1 in NATURE
  • 2010-06-27 An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase in NATURE BIOTECHNOLOGY
  • 2009-09-02 A dimerization-dependent mechanism drives RAF catalytic activation in NATURE
  • 2009-08 Grb-ing hold of insulin signaling in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2009-06-29 Characterization of Kinase Target Phosphorylation Consensus Motifs Using Peptide SPOT Arrays in PEPTIDE MICROARRAYS
  • 2009-06-29 Rapid Identification of Linear Protein Domain Binding Motifs Using Peptide SPOT Arrays in PEPTIDE MICROARRAYS
  • 2006-01-22 Sequence-specific recognition of RNA hairpins by the SAM domain of Vts1p in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2003-10 Bone recognition mechanism of porcine osteocalcin from crystal structure in NATURE
  • 2003-07-13 The RNA-binding SAM domain of Smaug defines a new family of post-transcriptional regulators in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2002-09-23 The Sak polo-box comprises a structural domain sufficient for mitotic subcellular localization in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2001-11-29 Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication in NATURE
  • 2001-10-29 Structural and biochemical characterization of the type III secretion chaperones CesT and SigE in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 1999-01 The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 1997-02 Activation of the Sire-family tyrosine kinase Hck by SH3 domain displacement in NATURE
  • 1997-02 Crystal structure of the Src family tyrosine kinase Hck in NATURE
  • 1997 Characterization of Antifreeze Proteins from Winter Rye in PLANT COLD HARDINESS
  • 1995-06 Ice-binding structure and mechanism of an antifreeze protein from winter flounder in NATURE
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