Søren Brunak

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Publications in SciGraph latest 50 shown

  • 2018-12 Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios in BMC BIOINFORMATICS
  • 2018-12 Protective role of the vulture facial skin and gut microbiomes aid adaptation to scavenging in ACTA VETERINARIA SCANDINAVICA
  • 2018-12 The governance structure for data access in the DIRECT consortium: an innovative medicines initiative (IMI) project in LIFE SCIENCES, SOCIETY AND POLICY
  • 2018-12 A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links in NATURE PROTOCOLS
  • 2018-06 Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells in CELL DEATH & DISEASE
  • 2018-03-23 Unexplored therapeutic opportunities in the human genome in NATURE REVIEWS DRUG DISCOVERY
  • 2018-01 Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study in DIABETOLOGIA
  • 2018 The Interplay of Non-coding RNAs and X Chromosome Inactivation in Human Disease in SYSTEMS BIOLOGY
  • 2017-12 Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter in SCIENTIFIC REPORTS
  • 2017-10-13 Legacy data sharing to improve drug safety assessment: the eTOX project in NATURE REVIEWS DRUG DISCOVERY
  • 2017-08 Sequencing and de novo assembly of 150 genomes from Denmark as a population reference in NATURE
  • 2017-03 Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis in DIABETOLOGIA
  • 2017-01 A scored human protein–protein interaction network to catalyze genomic interpretation in NATURE METHODS
  • 2017 MicroRNAs, Regulatory Networks, and Comorbidities: Decoding Complex Systems in MICRORNA DETECTION AND TARGET IDENTIFICATION
  • 2016-12 Diagnosis trajectories of prior multi-morbidity predict sepsis mortality in SCIENTIFIC REPORTS
  • 2016-11 Transcriptional interactions suggest niche segregation among microorganisms in the human gut in NATURE MICROBIOLOGY
  • 2016-11 Ranking factors involved in diabetes remission after bariatric surgery using machine-learning integrating clinical and genomic biomarkers in NPJ GENOMIC MEDICINE
  • 2016-10 Network biology concepts in complex disease comorbidities in NATURE REVIEWS GENETICS
  • 2016-10 A genomic history of Aboriginal Australia in NATURE
  • 2016-07 Human gut microbes impact host serum metabolome and insulin sensitivity in NATURE
  • 2016-06 Human genome meeting 2016 in HUMAN GENOMICS
  • 2016-06 KinMutRF: a random forest classifier of sequence variants in the human protein kinase superfamily in BMC GENOMICS
  • 2016-05 Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci in NATURE GENETICS
  • 2016-01 Integration of Known DNA, RNA and Protein Biomarkers Provides Prediction of Anti-TNF Response in Rheumatoid Arthritis: Results from the COMBINE Study in MOLECULAR MEDICINE
  • 2015-12 Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios in NATURE COMMUNICATIONS
  • 2015-12 Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota in NATURE
  • 2015-10 Investigation of Human Cancers for Retrovirus by Low-Stringency Target Enrichment and High-Throughput Sequencing in SCIENTIFIC REPORTS
  • 2015-06 Population genomics of Bronze Age Eurasia in NATURE
  • 2015-02 Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients in LEUKEMIA
  • 2014-12 Temporal disease trajectories condensed from population-wide registry data covering 6.2 million patients in NATURE COMMUNICATIONS
  • 2014-12 Modules, networks and systems medicine for understanding disease and aiding diagnosis in GENOME MEDICINE
  • 2014-11 Bacterial diversity in snow on North Pole ice floes in EXTREMOPHILES
  • 2014-08 An integrated catalog of reference genes in the human gut microbiome in NATURE BIOTECHNOLOGY
  • 2014-08 Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics in NATURE METHODS
  • 2014-08 Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes in NATURE BIOTECHNOLOGY
  • 2014-06 Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium in DIABETOLOGIA
  • 2014-05 Erratum to: Dose-Specific Adverse Drug Reaction Identification in Electronic Patient Records: Temporal Data Mining in an Inpatient Psychiatric Population in DRUG SAFETY
  • 2014-04 Dose-Specific Adverse Drug Reaction Identification in Electronic Patient Records: Temporal Data Mining in an Inpatient Psychiatric Population in DRUG SAFETY
  • 2014-02 The genome of a Late Pleistocene human from a Clovis burial site in western Montana in NATURE
  • 2014-01 Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans in NATURE
  • 2013-12 A computational approach to chemical etiologies of diabetes in SCIENTIFIC REPORTS
  • 2013-12 Metagenomic species profiling using universal phylogenetic marker genes in NATURE METHODS
  • 2013-12 Transcriptome profiling of mice testes following low dose irradiation in REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY
  • 2013-08 Richness of human gut microbiome correlates with metabolic markers in NATURE
  • 2013-07 Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse in NATURE
  • 2013-01 Reply to 'Mining electronic health records: an additional perspective' in NATURE REVIEWS GENETICS
  • 2012-06 Mining electronic health records: towards better research applications and clinical care in NATURE REVIEWS GENETICS
  • 2011-12 Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response in BMC BIOINFORMATICS
  • 2011-10 SignalP 4.0: discriminating signal peptides from transmembrane regions in NATURE METHODS
  • 2011-06-08 Enterotypes of the human gut microbiome in NATURE
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