Rolf Larsson

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Publications in SciGraph latest 50 shown

  • 2017-12 In Vitro and In Vivo Biocompatibility Evaluation of Polyallylamine and Macromolecular Heparin Conjugates Modified Alginate Microbeads in SCIENTIFIC REPORTS
  • 2017-07 Mass spectrometry based metabolomics for in vitro systems pharmacology: pitfalls, challenges, and computational solutions in METABOLOMICS
  • 2016-12 In vitro and in vivo activity of melflufen (J1) in lymphoma in BMC CANCER
  • 2016-12 Iron chelators target both proliferating and quiescent cancer cells in SCIENTIFIC REPORTS
  • 2015-12 Drug Sensitivity Testing in Cytoreductive Surgery and Intraperitoneal Chemotherapy of Pseudomyxoma Peritonei in ANNALS OF SURGICAL ONCOLOGY
  • 2015-12 DNA methylation-based subtype prediction for pediatric acute lymphoblastic leukemia in CLINICAL EPIGENETICS
  • 2015-11 In vitro discovery of promising anti-cancer drug combinations using iterative maximisation of a therapeutic index in SCIENTIFIC REPORTS
  • 2015-04 Drug screen in patient cells suggests quinacrine to be repositioned for treatment of acute myeloid leukemia in BLOOD CANCER JOURNAL
  • 2014-12 Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments in NATURE COMMUNICATIONS
  • 2014-12 Benchmarking of gastric cancer sensitivity to anti-cancer drugs ex vivo as a basis for drug selection in systemic and intraperitoneal therapy in JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
  • 2014-09 Label free high throughput screening for apoptosis inducing chemicals using time-lapse microscopy signal processing in APOPTOSIS
  • 2014-05 What is the link between temperature and carbon dioxide levels? A Granger causality analysis based on ice core data in THEORETICAL AND APPLIED CLIMATOLOGY
  • 2013-12 Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance in BMC CANCER
  • 2013-12 Effects of hypoxia on human cancer cell line chemosensitivity in BMC CANCER
  • 2013-12 Activity ex vivo of cytotoxic drugs in patient samples of peritoneal carcinomatosis with special focus on colorectal cancer in BMC CANCER
  • 2013-12 Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer in JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • 2013-09 Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia in GENOME BIOLOGY
  • 2013-06 Gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system in INVESTIGATIONAL NEW DRUGS
  • 2013 Evaluation of the Blood Compatibility of Materials, Cells, and Tissues: Basic Concepts, Test Models, and Practical Guidelines in COMPLEMENT THERAPEUTICS
  • 2012-12 Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma in BMC CANCER
  • 2012-08 The novel tyrosine kinase inhibitor AKN-028 has significant antileukemic activity in cell lines and primary cultures of acute myeloid leukemia in BLOOD CANCER JOURNAL
  • 2012-03 In vitro evaluation of clinical activity and toxicity of anticancer drugs using tumor cells from patients and cells representing normal tissues in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2011-12 Brunn: An open source laboratory information system for microplates with a graphical plate layout design process in BMC BIOINFORMATICS
  • 2011-12 Inhibition of proteasome deubiquitinating activity as a new cancer therapy in NATURE MEDICINE
  • 2010-05 Safety and efficacy of NAD depleting cancer drugs: results of a phase I clinical trial of CHS 828 and overview of published data in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2009-12 Combination analyses of anti-cancer drugs on human neuroendocrine tumor cell lines in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2009-10 Characterization of the cytotoxic activity of the indoloquinoline alkaloid cryptolepine in human tumour cell lines and primary cultures of tumour cells from patients in INVESTIGATIONAL NEW DRUGS
  • 2009-06 In vitro activity of bortezomib in cultures of patient tumour cells—potential utility in haematological malignancies in MEDICAL ONCOLOGY
  • 2009-01 Dic(9;20)(p13;q11) in childhood acute lymphoblastic leukaemia is related to low cellular resistance to asparaginase, cytarabine and corticosteroids in LEUKEMIA
  • 2008-12 A PDMS-based disposable microfluidic sensor for CD4+ lymphocyte counting in BIOMEDICAL MICRODEVICES
  • 2008-08 The fluorometric microculture cytotoxicity assay in NATURE PROTOCOLS
  • 2008-06 The novel alkylating prodrug J1: diagnosis directed activity profile ex vivo and combination analyses in vitro in INVESTIGATIONAL NEW DRUGS
  • 2007-09 R-etodolac (SDX-101) and the related indole–pyran analogues SDX-308 and SDX-309 potentiate the antileukemic activity of standard cytotoxic agents in primary chronic lymphocytic leukaemia cells in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2007-08 Pharmacological profiling of novel non-COX-inhibiting indole-pyran analogues of etodolac reveals high solid tumour activity of SDX-308 in vitro in INVESTIGATIONAL NEW DRUGS
  • 2006-12 Screening of an annotated compound library for drug activity in a resistant myeloma cell line in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2005-08 Identification of molecular mechanisms for cellular drug resistance by combining drug activity and gene expression profiles in BRITISH JOURNAL OF CANCER
  • 2005-01 Cytotoxic activity of a new paclitaxel formulation, Pacliex, in vitro and in vivo in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2005-01 Translocation t(1;19) is related to low cellular drug resistance in childhood acute lymphoblastic leukaemia in LEUKEMIA
  • 2004-11 Antitumor efficacy and acute toxicity of the novel dipeptide melphalanyl-p-L-fluorophenylalanine ethyl ester (J1) in vivo in INVESTIGATIONAL NEW DRUGS
  • 2003-01 Small, novel proteins from the mistletoe Phoradendron tomentosum exhibit highly selective cytotoxicity to human breast cancer cells in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2002-09 Selection of chemotherapy by ex vivo assessment of tumor sensitivity to cytotoxic drugs in MEDICAL ONCOLOGY
  • 2002-05 CHS 828 Inhibits Neuroblastoma Growth in Mice Alone and in Combination with Antiangiogenic Drugs in PEDIATRIC RESEARCH
  • 2002 A New Antibody Recognizing the vIII Mutation of Human Epidermal Growth Factor Receptor in TUMOR BIOLOGY
  • 2000-12 Determination of drug effect on tumour cells, host animal toxicity and drug pharmacokinetics in a hollow-fibre model in rats in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2000-05 Cellular cytotoxic drug sensitivity in children with acute leukemia and Down's syndrome: an explanation to differences in clinical outcome? in LEUKEMIA
  • 1999-09 Topoisomerase II-mediated alterations of K562 drug resistant sublines in MEDICAL ONCOLOGY
  • 1999 Is In Vitro Sensitivity of Blast Cells Correlated to Therapeutic Effect in Childhood Acute Lymphoblastic Leukemia? in DRUG RESISTANCE IN LEUKEMIA AND LYMPHOMA III
  • 1999 In Vitro Cytotoxic Drug Activity and In Vivo Pharmacokinetics in Childhood Acute Myeloid Leukemia in DRUG RESISTANCE IN LEUKEMIA AND LYMPHOMA III
  • 1998-10 Synergistic interactions of combinations of topotecan with standard drugs in primary cultures of human tumor cells from patients in EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
  • 1998-08 Comparison of the cytotoxic activity of melphalan with L-prolyl-m-L-sarcolysyl-L-p-fluorophenylalanine in human tumour cell lines and primary cultures of tumour cells from patients in BRITISH JOURNAL OF CANCER
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