Hm Pinedo


Ontology type: schema:Person     


Person Info

NAME

Hm

SURNAME

Pinedo

Publications in SciGraph latest 50 shown

  • 2007-03 Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels in BRITISH JOURNAL OF CANCER
  • 2006-10 Pharmacology of the paclitaxel–cisplatin, gemcitabine–cisplatin, and paclitaxel–gemcitabine combinations in patients with advanced non-small cell lung cancer in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2006-06 CD13/Aminopeptidase N overexpression by basic fibroblast growth factor mediates enhanced invasiveness of 1F6 human melanoma cells in BRITISH JOURNAL OF CANCER
  • 2005-03 Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11 in BRITISH JOURNAL OF CANCER
  • 2004 Angiogenesis: a potential target for therapy of soft tissue sarcomas in TARGETING TREATMENT OF SOFT TISSUE SARCOMAS
  • 2003-03 Role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in fluoropyrimidine sensitivity in BRITISH JOURNAL OF CANCER
  • 2002-09 Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity in BRITISH JOURNAL OF CANCER
  • 2002-04 A phase II study of active specific immunotherapy and5-FU/Leucovorin as adjuvant therapy for stage III colon carcinoma in BRITISH JOURNAL OF CANCER
  • 2002-03 A fully human anti-Ep-CAM scFv-beta-glucuronidase fusion protein for selective chemotherapy with a glucuronide prodrug in BRITISH JOURNAL OF CANCER
  • 2002-02 Extensive early apoptosis in frozen–thawed CD34-positive stem cells decreases threshold doses for haematological recovery after autologous peripheral blood progenitor cell transplantation in BONE MARROW TRANSPLANTATION
  • 2002 Kinetics of Reduced Folate Carrier-and Membrane-Associated Folate Receptor-Mediated Transport of Antifolates in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 2002 5-Fluorouracil Induction of Fas and Apoptosis in Colon Cancer Patients: Relation of Clinical Outcome with Thymidylate Synthase, Mcl-1 and Rb in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 2002 Role of P53 Status on Sensitivity to Thymidylate Synthase Inhibitors and Induction of Apoptosis in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 2001-03 Adjuvant Treatment of Colorectal Cancer: Towards Tumor-specific Immunotherapies in CANCER AND METASTASIS REVIEWS
  • 2001 A novel doxorubicin-glucuronide prodrug DOX-GA3 for tumour-selective chemotherapy: distribution and efficacy in experimental human ovarian cancer in BRITISH JOURNAL OF CANCER
  • 2000-10 Sequence dependent effect of paclitaxel on gemcitabine metabolism in relation to cell cycle and cytotoxicity in non-small-cell lung cancer cell lines in BRITISH JOURNAL OF CANCER
  • 2000-10 Drug resistance features and S-phase fraction as possible determinants for drug response in a panel of human ovarian cancer xenografts in BRITISH JOURNAL OF CANCER
  • 2000-06 P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy in LEUKEMIA
  • 1999-09 Potent interaction of flavopiridol with MRP1 in BRITISH JOURNAL OF CANCER
  • 1999-02 Do P-glycoprotein and major vault protein (MVP/LRP) expression correlate with in vitro daunorubicin resistance in acute myeloid leukemia? in LEUKEMIA
  • 1998-12 Characterization of human soft-tissue sarcoma xenografts for use in secondary drug screening in BRITISH JOURNAL OF CANCER
  • 1998-12 The efficacy of the anthracycline prodrug daunorubicin-GA3 in human ovarian cancer xenografts in BRITISH JOURNAL OF CANCER
  • 1998-12 Changes in L-selectin expression on CD34-positive cells upon cryopreservation of peripheral blood stem cell transplants in BONE MARROW TRANSPLANTATION
  • 1998-02 Prognostic role of clinical, pathological and biological characteristics in patients with locally advanced breast cancer in BRITISH JOURNAL OF CANCER
  • 1998 Determinants of the Therapeutic Efficacy of Thymidylate Synthase Inhibitors in PURINE AND PYRIMIDINE METABOLISM IN MAN IX
  • 1997-10 Highly sensitive and specific detection of P-glycoprotein function for haematological and solid tumour cells using a novel nucleic acid stain in BRITISH JOURNAL OF CANCER
  • 1997-07 Theoretical and practical considerations for the measurement of P-glycoprotein function in acute myeloid leukemia in LEUKEMIA
  • 1996-12 Functional detection of MDRI/P190 mediated multidrug resistance in tumour cells by flow cytometry in BRITISH JOURNAL OF CANCER
  • 1996-10 Continuous infusion or subcutaneous injection of granulocyte-macrophage colony-stimulating factor: increased efficacy and reduced toxicity when given subcutaneously in BRITISH JOURNAL OF CANCER
  • 1996-07 p53 and P-glycoprotein are often co-expressed and are associated with poor prognosis in breast cancer in BRITISH JOURNAL OF CANCER
  • 1995-09 Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry in BRITISH JOURNAL OF CANCER
  • 1995-06 The drug resistance-related protein LRP is the human major vault protein in NATURE MEDICINE
  • 1994-01 Comparison of two anthracycline-based prodrugs for activation by a monoclonal antibody-β-glucuronidase conjugate in the specific treatment of cancer in CELL BIOCHEMISTRY AND BIOPHYSICS
  • 1993-11 Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells in BRITISH JOURNAL OF CANCER
  • 1993-11 Changes in subcellular doxorubicin distribution and cellular accumulation alone can largely account for doxorubicin resistance in SW-1573 lung cancer and MCF-7 breast cancer multidrug resistant tumour cells in BRITISH JOURNAL OF CANCER
  • 1993-07 Prolonged retention of high concentrations of 5-fluorouracil in human and murine tumors as compared with plasma in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 1993-02 Cortisol is transported by the multidrug resistance gene product P-glycoprotein in BRITISH JOURNAL OF CANCER
  • 1991-11 Early multidrug resistance, defined by changes in intracellular doxorubicin distribution, independent of P-glycoprotein in BRITISH JOURNAL OF CANCER
  • 1990-10 The polyoxyethylene castor oil Cremophor EL modifies multidrug resistance in BRITISH JOURNAL OF CANCER
  • 1990-07 Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded ΦX174 DNA in BRITISH JOURNAL OF CANCER
  • 1990-07 Cyclosporin A and verapamil have different effects on energy metabolism in multidrug-resistant tumour cells in BRITISH JOURNAL OF CANCER
  • 1989-03 Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes in BRITISH JOURNAL OF CANCER
  • 1989 The relationship between dihydroorotic acid dehydrogenase and in vitro and in vivo cytostatic effects of brequinar sodium (DUP-785; NSC 368390). in PURINE AND PYRIMIDINE METABOLISM IN MAN VI
  • 1989 Fluoropyrimidine metabolism in human head and neck cancer xenografts and murine colon tumors. in PURINE AND PYRIMIDINE METABOLISM IN MAN VI
  • 1988-05 Uridine induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 1988-03 In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil in BRITISH JOURNAL OF CANCER
  • 1988-02 Uridine-induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 1987-09 Inhibition of pyrimidine de novo synthesis by DUP-785 (NSC 368390) in INVESTIGATIONAL NEW DRUGS
  • 1986-02 Pharmacokinetics of free and total platinum species after rapid and prolonged infusions of cisplatin in CLINICAL PHARMACOLOGY & THERAPEUTICS
  • 1986 Toxicity and Antitumor Effect of 5-Fluorouracil and its Rescue by Uridine in PURINE AND PYRIMIDINE METABOLISM IN MAN V
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