Karen H Vousden

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Karen H



Publications in SciGraph latest 50 shown

  • 2018-12 Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels in NATURE COMMUNICATIONS
  • 2018-12 p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant in CANCER & METABOLISM
  • 2018-10-13 Direct Estimation of Metabolic Flux by Heavy Isotope Labeling Simultaneous with Pathway Inhibition: Metabolic Flux Inhibition Assay in METABOLIC SIGNALING
  • 2018-03 Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 in CELL DEATH & DIFFERENTIATION
  • 2017-12 Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo in SCIENTIFIC REPORTS
  • 2017-08 Corrigendum: Modulating the therapeutic response of tumours to dietary serine and glycine starvation in NATURE
  • 2017-07 Structural analysis of MDM2 RING separates degradation from regulation of p53 transcription activity in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2017-04-19 Modulating the therapeutic response of tumours to dietary serine and glycine starvation in NATURE
  • 2017-02 One carbon, many roads in CELL DEATH & DIFFERENTIATION
  • 2016-12 Intrinsic aggregation propensity of the p63 and p73 TI domains correlates with p53R175H interaction and suggests further significance of aggregation events in the p53 family in CELL DEATH & DIFFERENTIATION
  • 2016-10 Serine and one-carbon metabolism in cancer in NATURE REVIEWS CANCER
  • 2015-08 p53- and p73-independent activation of TIGAR expression in vivo in CELL DEATH & DISEASE
  • 2015-08 Functional interplay between MDM2, p63/p73 and mutant p53 in ONCOGENE
  • 2015-07 p53 in survival, death and metabolic health: a lifeguard with a licence to kill in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2014-12 TIGAR, TIGAR, burning bright in CANCER & METABOLISM
  • 2014-06 Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo in CELL DEATH & DIFFERENTIATION
  • 2014-06 Functions of TAp63 and p53 in restraining the development of metastatic cancer in ONCOGENE
  • 2014-05 The in vivo function of TIGAR, a p53 target gene that regulates glucose metabolism in CANCER & METABOLISM
  • 2014-05 The Regulation of TIGAR in CANCER & METABOLISM
  • 2013-04 Corrigendum: Serine is a natural ligand and allosteric activator of pyruvate kinase M2 in NATURE
  • 2013-03 Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion in ONCOGENE
  • 2013-01 p53 mutations in cancer in NATURE CELL BIOLOGY
  • 2012-12-16 Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells in NATURE
  • 2012-12 Erratum to: Contribution of membrane localization to the apoptotic activity of PUMA in APOPTOSIS
  • 2012-11 Serine is a natural ligand and allosteric activator of pyruvate kinase M2 in NATURE
  • 2012-06 The in vivofunction of the p53 target gene TIGAR in BMC PROCEEDINGS
  • 2012-02 Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2011-05 Erratum to: Metabolic regulation by p53 in JOURNAL OF MOLECULAR MEDICINE
  • 2011-04 p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival in CELL RESEARCH
  • 2011-03 Metabolic regulation by p53 in JOURNAL OF MOLECULAR MEDICINE
  • 2009-10 p53 and metabolism in NATURE REVIEWS CANCER
  • 2009-08 PUMA- and Bax-induced autophagy contributes to apoptosis in CELL DEATH & DIFFERENTIATION
  • 2009-08 Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes in CELL DEATH & DIFFERENTIATION
  • 2008-10 Cooperation between the ribosomal proteins L5 and L11 in the p53 pathway in ONCOGENE
  • 2008-05 A role for Numb in p53 stabilization in GENOME BIOLOGY
  • 2008-01 Contribution of membrane localization to the apoptotic activity of PUMA in APOPTOSIS
  • 2007-06 p73 supports cellular growth through c-Jun-dependent AP-1 transactivation in NATURE CELL BIOLOGY
  • 2007-04 p53 in health and disease in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2007-03-18 C-terminal modifications regulate MDM2 dissociation and nuclear export of p53 in NATURE CELL BIOLOGY
  • 2007-02 Coping with stress: multiple ways to activate p53 in ONCOGENE
  • 2005-12 Savior and slayer: the two faces of p53 in NATURE MEDICINE
  • 2005-04 ASPP1 and ASPP2 are new transcriptional targets of E2F in CELL DEATH & DIFFERENTIATION
  • 2005-03 HDM2 phosphorylation by MAPKAP kinase 2 in ONCOGENE
  • 2004-07 PML regulates p53 stability by sequestering Mdm2 to the nucleolus in NATURE CELL BIOLOGY
  • 2004-04 p73-alpha is capable of inducing scotin and ER stress in ONCOGENE
  • 2004-01 Cancer: Guarding the guardian? in NATURE
  • 2002-10 Cancer: Pinning a change on p53 in NATURE
  • 2002-08 Live or let die: the cell's response to p53 in NATURE REVIEWS CANCER
  • 2002-08 p73: Friend or foe in tumorigenesis in NATURE REVIEWS CANCER
  • 2002-03 Phosphorylation of HDM2 by Akt in ONCOGENE
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