Nick Barker

Ontology type: schema:Person     

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Publications in SciGraph latest 50 shown

  • 2018-09 Author Correction: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6 in NATURE
  • 2018-05 RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6 in NATURE
  • 2018 Role of Lgr5-Expressing Stem Cells in Epithelial Renewal and Cancer in the Reproductive Tract in CELL BIOLOGY OF THE OVARY
  • 2017-07 Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach in NATURE CELL BIOLOGY
  • 2016-12 Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma in NATURE COMMUNICATIONS
  • 2016-04 Quantifying Lgr5-positive stem cell behaviour in the pyloric epithelium in SCIENTIFIC REPORTS
  • 2016-03 Organoids as an in vitro model of human development and disease in NATURE CELL BIOLOGY
  • 2015-10 Ovary and fimbrial stem cells: biology, niche and cancer origins in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2014-08 Lgr5 marks stem/progenitor cells in ovary and tubal epithelia in NATURE CELL BIOLOGY
  • 2014-01 Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2013-04 Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation in ONCOGENE
  • 2012-12 Stem cell reprogramming as a driver of basal cell carcinoma in NATURE CELL BIOLOGY
  • 2012-10 Dll1+ secretory progenitor cells revert to stem cells upon crypt damage in NATURE CELL BIOLOGY
  • 2012-06 Lgr5 and Lgr6 as markers to study adult stem cell roles in self-renewal and cancer in ONCOGENE
  • 2011-09 Gastrointestinal stem cells in self-renewal and cancer in JOURNAL OF GASTROENTEROLOGY
  • 2011-08 Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling in NATURE
  • 2011-01 Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts in NATURE
  • 2009-10 p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice in NATURE GENETICS
  • 2009-05 Single Lgr5 stem cells build crypt–villus structures in vitro without a mesenchymal niche in NATURE
  • 2009-01 Crypt stem cells as the cells-of-origin of intestinal cancer in NATURE
  • 2008-11 Lgr5 marks cycling, yet long-lived, hair follicle stem cells in NATURE GENETICS
  • 2008-10 The upstream components of the Wnt signalling pathway in the dynamic EMT and MET associated with colorectal cancer progression in CLINICAL & EXPERIMENTAL METASTASIS
  • 2008 Detection of β-Catenin Localization by Immunohistochemistry in WNT SIGNALING
  • 2008 The Canonical Wnt/β-Catenin Signalling Pathway in WNT SIGNALING
  • 2007-10-25 Identification of stem cells in small intestine and colon by marker gene Lgr5 in NATURE
  • 2006-12 Mining the Wnt pathway for cancer therapeutics in NATURE REVIEWS DRUG DISCOVERY
  • 2002-05 Ligand activation of peroxisome proliferator-activated receptor γ induces apoptosis of leukemia cells by down-regulating the c-myc gene expression via blockade of the Tcf-4 activity in CELL DEATH & DIFFERENTIATION
  • 1998-08 Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4 in NATURE GENETICS
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