Gerrit Jansen


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Person Info

NAME

Gerrit

SURNAME

Jansen

Publications in SciGraph latest 50 shown

  • 2019-02 The folate receptor β as a macrophage-mediated imaging and therapeutic target in rheumatoid arthritis in DRUG DELIVERY AND TRANSLATIONAL RESEARCH
  • 2018-10 Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide in INVESTIGATIONAL NEW DRUGS
  • 2018-02 Positioning of proteasome inhibitors in therapy of solid malignancies in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2017-12 (Immuno)proteasomes as therapeutic target in acute leukemia in CANCER AND METASTASIS REVIEWS
  • 2017-12 In-vivo monitoring of anti-folate therapy in arthritic rats using [18F]fluoro-PEG-folate and positron emission tomography in ARTHRITIS RESEARCH & THERAPY
  • 2017-12 Bortezomib resistance in multiple myeloma is associated with increased serine synthesis in CANCER & METABOLISM
  • 2016-12 Proteasome subunit expression analysis and chemosensitivity in relapsed paediatric acute leukaemia patients receiving bortezomib-containing chemotherapy in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2015-12 Effect of prednisone on type I interferon signature in rheumatoid arthritis: consequences for response prediction to rituximab in ARTHRITIS RESEARCH & THERAPY
  • 2015-12 Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2015-12 Proteasome inhibitors as experimental therapeutics of autoimmune diseases in ARTHRITIS RESEARCH & THERAPY
  • 2014-12 Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine in SPRINGERPLUS
  • 2014-12 Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2014-05 Folates provoke cellular efflux and drug resistance of substrates of the multidrug resistance protein 1 (MRP1) in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2014-04 Het voorspellen van de gevoeligheid van kinderleukemiecellen voor proteasoomremmers in TIJDSCHRIFT VOOR KINDERGENEESKUNDE
  • 2014-04 Positioning of aminopeptidase inhibitors in next generation cancer therapy in AMINO ACIDS
  • 2014-04 Promising potential of new generation translocator protein tracers providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritis in ARTHRITIS RESEARCH & THERAPY
  • 2014 Preclinical Studies on the Molecular Basis of Bortezomib Resistance and Modalities to Overcome Resistance in Hematological Malignancies in RESISTANCE TO PROTEASOME INHIBITORS IN CANCER
  • 2013-12 Overcoming bortezomib resistance in human B cells by anti-CD20/rituximab-mediated complement-dependent cytotoxicity and epoxyketone-based irreversible proteasome inhibitors in EXPERIMENTAL HEMATOLOGY & ONCOLOGY
  • 2013-04 Evaluation of the novel folate receptor ligand [18F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis in ARTHRITIS RESEARCH & THERAPY
  • 2013-02 Sensitivity of Pediatric Acute Leukemia Cells to Bortezomib: Correlations with Proteasome Subunit Expression in TIJDSCHRIFT VOOR KINDERGENEESKUNDE
  • 2012-04 Impaired bortezomib binding to mutant β5 subunit of the proteasome is the underlying basis for bortezomib resistance in leukemia cells in LEUKEMIA
  • 2011-07 High susceptibility of c-KIT+CD34+ precursors to prolonged doxorubicin exposure interferes with Langerhans cell differentiation in a human cell line model in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2011-04-08 Folate Receptor Targeted Thymidylate Synthase Inhibitors in TARGETED DRUG STRATEGIES FOR CANCER AND INFLAMMATION
  • 2009-04 Impact of cellular folate status and epidermal growth factor receptor expression on BCRP/ABCG2-mediated resistance to gefitinib and erlotinib in BRITISH JOURNAL OF CANCER
  • 2008-11 Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2008-03 Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors in BRITISH JOURNAL OF CANCER
  • 2007-09 Modulation of folate uptake in cultured human colon adenocarcinoma Caco-2 cells by dietary compounds in EUROPEAN JOURNAL OF NUTRITION
  • 2007-01 Drug Insight: resistance to methotrexate and other disease-modifying antirheumatic drugs—from bench to bedside in NATURE REVIEWS RHEUMATOLOGY
  • 2006-12 Mutant Gly482 and Thr482 ABCG2 mediate high-level resistance to lipophilic antifolates in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2006-07 Multidrug resistance proteins and folate supplementation: therapeutic implications for antifolates and other classes of drugs in cancer treatment in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2005-02 Inhibition of tumour necrosis factor alpha production by activated T cells of rheumatoid arthritis patients by novel anti-folate drugs: an ex vivopilot study in ARTHRITIS RESEARCH & THERAPY
  • 2005-02 Differential expression of multidrug resistance-related proteins on monocyte-derived macrophages from rheumatoid arthritis patients in ARTHRITIS RESEARCH & THERAPY
  • 2004-02 Multidrug resistance proteins and DMARD efficacy in rheumatoid arthritis in ARTHRITIS RESEARCH & THERAPY
  • 2002-02 Molecular mechanisms of resistance to disease modifying antirheumatic drugs (DMARDs) in ARTHRITIS RESEARCH & THERAPY
  • 2002 Kinetics of Reduced Folate Carrier-and Membrane-Associated Folate Receptor-Mediated Transport of Antifolates in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 2002 Role of Multidrug Resistance Proteins (MRP) in Resistance to Antifolates and Folate Homeostasis in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 2002 Induction of Resistance to the Multi-Targeted Antifolate MTA (LY231514) in Widr Human Colon Cancer Cells in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 2000-12 mRNA expression levels of methotrexate resistance-related proteins in childhood leukemia as determined by a standardized competitive template-based RT-PCR method in LEUKEMIA
  • 1999-05 Continuous Exposure to Methotrexate (MTX) Overcomes Resistance in Childhood Acute Myeloid Leukemia (AML) in Vitro in PEDIATRIC RESEARCH
  • 1999 Lack of Cross-Resistance Between Prednisolone and Methotrexate in Childhood Acute Lymphoblastic Leukemia? in DRUG RESISTANCE IN LEUKEMIA AND LYMPHOMA III
  • 1998 Determinants of the Therapeutic Efficacy of Thymidylate Synthase Inhibitors in PURINE AND PYRIMIDINE METABOLISM IN MAN IX
  • 1996-06 Functional aspects of membrane folate receptors in human breast cancer cells with transport-related resistance to methotrexate in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 1993 Transformation of an L-Cell Line with the DNA Coding for the Reduced-Folate/Methotrexate Transporter Protein from a CCRF-CEM Human Leukemia Cell Line in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 1993 The Reduced Folate/Methotrexate Carrier and a Membrane-Associated Folate Binding Protein as Transport Routes for Novel Antifolates: Structure-Activity Relationships in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 1993 Detergent-Insolubility During the Biosynthesis of Membrane Folate Receptor-2 in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 1993 Identification of a Reduced Folate/Methotrexate Carrier in Human KB-Cells Expressing High Levels of Membrane Associated Folate Binding Protein in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 1993 Variable Pharmacodynamics of Antifolates in Squamous Cell Carcinoma of the Head and Neck in CHEMISTRY AND BIOLOGY OF PTERIDINES AND FOLATES
  • 1991-03 Growth-inhibitory effects of 5,10-dideazatetrahydrofolic acid on variant murine L1210 and human CCRF-CEM leukemia cells with different membrane-transport characteristics for (anti)folate compounds in CANCER CHEMOTHERAPY AND PHARMACOLOGY
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