Alan Melcher

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Publications in SciGraph latest 50 shown

  • 2018-06 Synergistic antitumour effects of rapamycin and oncolytic reovirus in CANCER GENE THERAPY
  • 2017-01 Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumour therapy in GENE THERAPY
  • 2016-12 A phase-I trial of pre‐operative, margin intensive, stereotactic body radiation therapy for pancreatic cancer: the ‘SPARC’ trial protocol in BMC CANCER
  • 2016-11 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2016-11 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2016-04 Oncolytic vaccinia virus as a vector for therapeutic sodium iodide symporter gene therapy in prostate cancer in GENE THERAPY
  • 2015-12 Oncolytic immunotherapy for the treatment of non-muscle invasive bladder cancer using intravesical coxsackievirus A21 in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2015-12 Phase I/II storm study: Intravenous delivery of a novel oncolytic immunotherapy agent, Coxsackievirus A21, in advanced cancer patients in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2015-09 Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia in LEUKEMIA
  • 2015-02 Cell migration in paediatric glioma; characterisation and potential therapeutic targeting in BRITISH JOURNAL OF CANCER
  • 2014-03 Synergistic cytotoxicity of radiation and oncolytic Lister strain vaccinia in V600D/EBRAF mutant melanoma depends on JNK and TNF-α signaling in ONCOGENE
  • 2013-12 Detecting and targeting tumor relapse by its resistance to innate effectors at early recurrence in NATURE MEDICINE
  • 2013-05 Synergistic cytotoxicity of oncolytic reovirus in combination with cisplatin–paclitaxel doublet chemotherapy in GENE THERAPY
  • 2013-01 Measles virus causes immunogenic cell death in human melanoma in GENE THERAPY
  • 2012-12 Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway in BMC CANCER
  • 2012-10 Reovirus-associated reduction of microRNA-let-7d is related to the increased apoptotic death of cancer cells in clinical samples in MODERN PATHOLOGY
  • 2012-09 Corrigendum: Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors in NATURE MEDICINE
  • 2012-04 Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma in NATURE BIOTECHNOLOGY
  • 2012-01 Combination of a fusogenic glycoprotein, pro-drug activation and oncolytic HSV as an intravesical therapy for superficial bladder cancer in BRITISH JOURNAL OF CANCER
  • 2012-01 Enhancing the immunogenicity of tumour lysate-loaded dendritic cell vaccines by conjugation to virus-like particles in BRITISH JOURNAL OF CANCER
  • 2011-12 Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer in BMC CANCER
  • 2011-12 Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-κB mediated and supports innate and adaptive anti-tumour immune priming in MOLECULAR CANCER
  • 2011-09 Immune activation by combination human lymphokine-activated killer and dendritic cell therapy in BRITISH JOURNAL OF CANCER
  • 2011-07 Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors in NATURE MEDICINE
  • 2010-12 Differential effects of Paclitaxel on dendritic cell function in BMC IMMUNOLOGY
  • 2010-08 Locoregional intravascular viral therapy of cancer: precision guidance for Paris's arrow? in GENE THERAPY
  • 2010-02 Single-cycle viral gene expression, rather than progressive replication and oncolysis, is required for VSV therapy of B16 melanoma in GENE THERAPY
  • 2009-05 Dendritic cells and T cells deliver oncolytic reovirus for tumour killing despite pre-existing anti-viral immunity in GENE THERAPY
  • 2009-01 Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery in GENE THERAPY
  • 2008-09 Inflammatory tumour cell killing by oncolytic reovirus for the treatment of melanoma in GENE THERAPY
  • 2008-06 Autologous versus allogeneic peptide-pulsed dendritic cells for anti-tumour vaccination: expression of allogeneic MHC supports activation of antigen specific T cells, but impairs early naïve cytotoxic priming and anti-tumour therapy in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2008-06 Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial in GENE THERAPY
  • 2008-04 Loading of oncolytic vesicular stomatitis virus onto antigen-specific T cells enhances the efficacy of adoptive T-cell therapy of tumors in GENE THERAPY
  • 2008-03 Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo in GENE THERAPY
  • 2008-01 Purging metastases in lymphoid organs using a combination of antigen-nonspecific adoptive T cell therapy, oncolytic virotherapy and immunotherapy in NATURE MEDICINE
  • 2007-11 Preoperative radiotherapy combined with 5 days per week capecitabine chemotherapy in locally advanced rectal cancer in BRITISH JOURNAL OF CANCER
  • 2006-01 Fusogenic membrane glycoprotein-mediated tumour cell fusion activates human dendritic cells for enhanced IL-12 production and T-cell priming in GENE THERAPY
  • 2005-04 Immunosuppressive effects of radiation on human dendritic cells: reduced IL-12 production on activation and impairment of naïve T-cell priming in BRITISH JOURNAL OF CANCER
  • 2005 Fusogeneic Membrane Glycoproteins for Cancer Gene Therapy in CANCER GENE THERAPY
  • 2004-09 A simple method to cure established tumors by inflammatory killing of normal cells in NATURE BIOTECHNOLOGY
  • 2004-07 Induction of cell stress through gene transfer of an engineered heat shock transcription factor enhances tumor immunogenicity in GENE THERAPY
  • 2004-04 Heated tumour cells of autologous and allogeneic origin elicit anti-tumour immunity in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2003-09 A new genetic method to generate and isolate small, short-lived but highly potent dendritic cell-tumor cell hybrid vaccines in NATURE MEDICINE
  • 2003-05 Concurrent chemoradiotherapy for squamous cell carcinoma of the anus using a shrinking field radiotherapy technique without a boost in BRITISH JOURNAL OF CANCER
  • 1999-12 Apoptosis or necrosis for tumor immunotherapy: what's in a name? in JOURNAL OF MOLECULAR MEDICINE
  • 1998-05 Tumor immunogenicity is determined by the mechanism of cell death via induction of heat shock protein expression in NATURE MEDICINE
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