Godefridus J Peters

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Godefridus J



Publications in SciGraph latest 50 shown

  • 2018-11-08 Cytidine deaminase enzymatic activity is a prognostic biomarker in gemcitabine/platinum-treated advanced non-small-cell lung cancer: a prospective validation study in BRITISH JOURNAL OF CANCER
  • 2018-10 Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide in INVESTIGATIONAL NEW DRUGS
  • 2018-07 Randomized phase 2 study of gemcitabine and cisplatin with or without vitamin supplementation in patients with advanced esophagogastric cancer in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2018-03 Cellular pharmacology studies of anticancer agents: recommendations from the EORTC-PAMM group in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2017-12 The allosteric AKT inhibitor MK2206 shows a synergistic interaction with chemotherapy and radiotherapy in glioblastoma spheroid cultures in BMC CANCER
  • 2017-12 Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2017-11 The potential of multi-compound nanoparticles to bypass drug resistance in cancer in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2017-07-11 Pharmacologically directed strategies in academic anticancer drug discovery based on the European NCI compounds initiative in BRITISH JOURNAL OF CANCER
  • 2017-06 Erratum to: Glutamate and α-ketoglutarate: key players in glioma metabolism in AMINO ACIDS
  • 2017 Hollow Fiber Assay in ENCYCLOPEDIA OF CANCER
  • 2017 Re-emerging Antimetabolites with Novel Mechanism of Action with Respect to Epigenetic Regulation: Basic Aspects in CHEMOTHERAPY FOR LEUKEMIA
  • 2017-01 Glutamate and α-ketoglutarate: key players in glioma metabolism in AMINO ACIDS
  • 2016-12 Alternative scheduling of pulsatile, high dose sunitinib efficiently suppresses tumor growth in JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
  • 2016-07 Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2016 The Role of MicroRNAs in Resistance to Current Pancreatic Cancer Treatment: Translational Studies and Basic Protocols for Extraction and PCR Analysis in CANCER DRUG RESISTANCE
  • 2016-01 Contemporary reviews on cancer treatment in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2015-12 Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia in JOURNAL OF HEMATOLOGY & ONCOLOGY
  • 2015-08 MiRNAs and Their Interference with the Main Molecular Mechanisms Responsible for Drug Resistance in Pancreatic Cancer in CURRENT PHARMACOLOGY REPORTS
  • 2015-04 Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib in CELLULAR ONCOLOGY
  • 2015-03 Tailoring heated intraperitoneal mitomycin C for peritoneal metastases originating from colorectal carcinoma: a translational approach to improve survival in BRITISH JOURNAL OF CANCER
  • 2015 Hollow Fiber Assay in ENCYCLOPEDIA OF CANCER
  • 2014-12 Overexpression of MRP4 (ABCC4) and MRP5 (ABCC5) confer resistance to the nucleoside analogs cytarabine and troxacitabine, but not gemcitabine in SPRINGERPLUS
  • 2014-06 The novel thymidylate synthase inhibitor trifluorothymidine (TFT) and TRAIL synergistically eradicate non-small cell lung cancer cells in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2014-05 Folates provoke cellular efflux and drug resistance of substrates of the multidrug resistance protein 1 (MRP1) in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2014-04 Positioning of aminopeptidase inhibitors in next generation cancer therapy in AMINO ACIDS
  • 2014-01 Synergistic interaction of novel lactate dehydrogenase inhibitors with gemcitabine against pancreatic cancer cells in hypoxia in BRITISH JOURNAL OF CANCER
  • 2013-12 Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360) in INVESTIGATIONAL NEW DRUGS
  • 2013-12 Overcoming bortezomib resistance in human B cells by anti-CD20/rituximab-mediated complement-dependent cytotoxicity and epoxyketone-based irreversible proteasome inhibitors in EXPERIMENTAL HEMATOLOGY & ONCOLOGY
  • 2013-12 USP1 deubiquitinase: cellular functions, regulatory mechanisms and emerging potential as target in cancer therapy in MOLECULAR CANCER
  • 2013-07 MAPK p38 and JNK have opposing activities on TRAIL-induced apoptosis activation in NSCLC H460 cells that involves RIP1 and caspase-8 and is mediated by Mcl-1 in APOPTOSIS
  • 2013-07 Non-canonical kinase signaling by the death ligand TRAIL in cancer cells: discord in the death receptor family in CELL DEATH & DIFFERENTIATION
  • 2012-10 Metabolism and accumulation of the lipophilic deoxynucleoside analogs elacytarabine and CP-4126 in INVESTIGATIONAL NEW DRUGS
  • 2011-12 Severe toxicity of capecitabine following uncomplicated treatment with 5-fluorouracil/leucovorin in MEDICAL ONCOLOGY
  • 2011-11 Preclinical emergence of vandetanib as a potent antitumour agent in mesothelioma: molecular mechanisms underlying its synergistic interaction with pemetrexed and carboplatin in BRITISH JOURNAL OF CANCER
  • 2011-06 Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models in INVESTIGATIONAL NEW DRUGS
  • 2011-04 Cellular pharmacology of multi- and duplex drugsconsisting of ethynylcytidine and 5-fluoro-2′-deoxyuridine in INVESTIGATIONAL NEW DRUGS
  • 2011-03-24 Analysis of Drug Interactions in CANCER CELL CULTURE
  • 2011-03 Thymidine phosphorylase in cancer cells stimulates human endothelial cell migration and invasion by the secretion of angiogenic factors in BRITISH JOURNAL OF CANCER
  • 2011-02 The semisynthetic flavonoid monoHER sensitises human soft tissue sarcoma cells to doxorubicin-induced apoptosis via inhibition of nuclear factor-κB in BRITISH JOURNAL OF CANCER
  • 2011 Hollow Fiber Assay in ENCYCLOPEDIA OF CANCER
  • 2009-04 Impact of cellular folate status and epidermal growth factor receptor expression on BCRP/ABCG2-mediated resistance to gefitinib and erlotinib in BRITISH JOURNAL OF CANCER
  • 2009-01 Combined assessment of EGFR pathway-related molecular markers and prognosis of NSCLC patients in BRITISH JOURNAL OF CANCER
  • 2009 Hollow Fiber Assay in ENCYCLOPEDIA OF CANCER
  • 2008-11 Dynamics of antifolate transport via the reduced folate carrier and the membrane folate receptor in murine leukaemia cells in vitro and in vivo in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2008-09 Molecular pathways involved in the synergistic interaction of the PKCβ inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells in BRITISH JOURNAL OF CANCER
  • 2008-08 [18F]FDG and [18F]FLT uptake in human breast cancer cells in relation to the effects of chemotherapy: an in vitro study in BRITISH JOURNAL OF CANCER
  • 2008-03 Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors in BRITISH JOURNAL OF CANCER
  • 2007-09 Modulation of folate uptake in cultured human colon adenocarcinoma Caco-2 cells by dietary compounds in EUROPEAN JOURNAL OF NUTRITION
  • 2007-03 Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels in BRITISH JOURNAL OF CANCER
  • 2007-01 The hollow fibre assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells in BRITISH JOURNAL OF CANCER
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