Jonathan A Fletcher


Ontology type: schema:Person     


Person Info

NAME

Jonathan A

SURNAME

Fletcher

Publications in SciGraph latest 50 shown

  • 2019-02 LMTK3 is essential for oncogenic KIT expression in KIT-mutant GIST and melanoma in ONCOGENE
  • 2017-06 Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors in ONCOGENE
  • 2017-03-08 MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation in NATURE COMMUNICATIONS
  • 2017 HER-2/neu in ENCYCLOPEDIA OF CANCER
  • 2016-12 No preclinical rationale for IGF1R directed therapy in chondrosarcoma of bone in BMC CANCER
  • 2016-11 Co-targeting of FAK and MDM2 triggers additive anti-proliferative effects in mesothelioma via a coordinated reactivation of p53 in BRITISH JOURNAL OF CANCER
  • 2016-10 Inhibition of Bcl-2 family members sensitizes mesenchymal chondrosarcoma to conventional chemotherapy: report on a novel mesenchymal chondrosarcoma cell line in LABORATORY INVESTIGATION
  • 2016-05 Inhibition of Bcl-2 family members sensitises soft tissue leiomyosarcomas to chemotherapy in BRITISH JOURNAL OF CANCER
  • 2014-11 PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors in NATURE GENETICS
  • 2014-06 A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations in NATURE GENETICS
  • 2014-06 Dystrophin is a tumor suppressor in human cancers with myogenic programs in NATURE GENETICS
  • 2014-05 Frequent expression of KIT in endometrial stromal sarcoma with YWHAE genetic rearrangement in MODERN PATHOLOGY
  • 2014-05 Multipoint targeting of the PI3K/mTOR pathway in mesothelioma in BRITISH JOURNAL OF CANCER
  • 2014-04 Genome-wide functional screening identifies CDC37 as a crucial HSP90-cofactor for KIT oncogenic expression in gastrointestinal stromal tumors in ONCOGENE
  • 2014 HER2/neu in ENCYCLOPEDIA OF CANCER
  • 2013-12 Anti-KIT designer T cells for the treatment of gastrointestinal stromal tumor in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2013-05 MED12 mutations in leiomyosarcoma and extrauterine leiomyoma in MODERN PATHOLOGY
  • 2012-10 Integrating Bioinformatics and Clinicopathological Research of Gastrointestinal Stromal Tumors: Identification of Aurora Kinase A as a Poor Risk Marker in ANNALS OF SURGICAL ONCOLOGY
  • 2011-04 AXL regulates mesothelioma proliferation and invasiveness in ONCOGENE
  • 2010-10 ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours in NATURE
  • 2010-08 Trisomy 18 is a consistent cytogenetic feature in pilomatricoma in MODERN PATHOLOGY
  • 2010-06 Absence of BRAF, NRAS, KRAS, HRAS Mutations, and RET/PTC Gene Rearrangements Distinguishes Dominant Nodules in Hashimoto Thyroiditis from Papillary Thyroid Carcinomas in ENDOCRINE PATHOLOGY
  • 2010-05 Carbonic anhydrase II. A novel biomarker for gastrointestinal stromal tumors in MODERN PATHOLOGY
  • 2010-02 Gastrointestinal stromal tumors in VIRCHOWS ARCHIV
  • 2009 HER-2/neu in ENCYCLOPEDIA OF CANCER
  • 2008-12 Molecular Detection of PPARγ Rearrangements and Thyroid Carcinoma in Preoperative Fine-Needle Aspiration Biopsies in ENDOCRINE PATHOLOGY
  • 2008-09 Molecular Detection of PPARγ Rearrangements and Thyroid Carcinoma in Preoperative Fine-Needle Aspiration Biopsies in ENDOCRINE PATHOLOGY
  • 2008-09 Protein kinase C-θ regulates KIT expression and proliferation in gastrointestinal stromal tumors in ONCOGENE
  • 2008-04 BRD–NUT oncoproteins: a family of closely related nuclear proteins that block epithelial differentiation and maintain the growth of carcinoma cells in ONCOGENE
  • 2007-11 KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase/AKT is a crucial survival pathway in ONCOGENE
  • 2007-09 KIT oncoprotein interactions in gastrointestinal stromal tumors: therapeutic relevance in ONCOGENE
  • 2007-05 An in vitro cytologic assay for evaluation of the KIT signaling pathway in gastrointestinal stromal tumors in MODERN PATHOLOGY
  • 2005-05 Aneurysmal bone cyst variant translocations upregulate USP6 transcription by promoter swapping with the ZNF9, COL1A1, TRAP150, and OMD genes in ONCOGENE
  • 2004-10 Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles in ONCOGENE
  • 2004-05 Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs) in ONCOGENE
  • 2004 Molecular biology and cytogenetics of soft tissue sarcomas: Relevance for targeted therapies in TARGETING TREATMENT OF SOFT TISSUE SARCOMAS
  • 2002-09-13 Chromogenic In Situ Hybridization and FISH in Pathology in MOLECULAR CYTOGENETICS
  • 2002-03 Peripheral Nerve Sheath Tumors from Patients with Neurofibromatosis Type 1 Do Not Have the Chromosomal Translocation t(X;18) in PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
  • 2002-03 Gains of Chromosome 8 in Pleuropulmonary Blastomas of Childhood (Reply) in PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
  • 2001-09 Gains of Chromosome 8 Are Confined to Mesenchymal Components in Pleuropulmonary Blastoma in PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
  • 2001-08 STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications in ONCOGENE
  • 2001-07 Correspondence Re: O'Sullivan MJ, Kyriakos M, Zhu X, Wick MR, Swanson PE, Dehner LP, Humphrey PA, Pfeifer JD: Malignant Peripheral Nerve Sheath Tumors With T(X;18). A Pathologic and Molecular Genetic Study. Mod Pathol 2000;13:1336–46 in MODERN PATHOLOGY
  • 2001 HER-2/neu in ENCYCLOPEDIC REFERENCE OF CANCER
  • 2000-09-22 HER-2/ neuOncogene Amplification Determined by Fluorescence In Situ Hybridization in MOLECULAR PATHOLOGY PROTOCOLS
  • 1998-01 FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome in NATURE GENETICS
  • 1998-01 Cystic Neuroblastoma: Emphasis on Gene Expression, Morphology, and Pathogenesis in PEDIATRIC AND DEVELOPMENTAL PATHOLOGY
  • 1997 Cytogenetics of soft tissue tumors in SOFT TISSUE SARCOMAS: PRESENT ACHIEVEMENTS AND FUTURE PROSPECTS
  • 1993-08 The Wilms tumour gene WT1 is expressed in murine mesoderm–derived tissues and mutated in a human mesothelioma in NATURE GENETICS
  • 1992-12 Molecular characterization of a 17q11.2 translocation in a malignant schwannoma cell line in HUMAN GENETICS
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