John Richard Griffiths


Ontology type: schema:Person     


Person Info

NAME

John Richard

SURNAME

Griffiths

Publications in SciGraph latest 50 shown

  • 2020-08-12 ApcMin/+ tumours and normal mouse small intestines show linear metabolite concentration and DNA cytosine hydroxymethylation gradients from pylorus to colon in SCIENTIFIC REPORTS
  • 2019-04-13 A Combined Chemical Derivatization/Mass Spectrometric Method for the Enhanced Detection and Relative Quantification of Protein Ubiquitination in MASS SPECTROMETRY OF PROTEINS
  • 2018-08 Carbonic anhydrase IX is a pH-stat that sets an acidic tumour extracellular pH in vivo in BRITISH JOURNAL OF CANCER
  • 2017-12-15 Correction to: The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models in EJNMMI RESEARCH
  • 2017-10-02 3′-Deoxy-3′-[18F]Fluorothymidine Uptake Is Related to Thymidine Phosphorylase Expression in Various Experimental Tumor Models in MOLECULAR IMAGING AND BIOLOGY
  • 2017-02-28 The action of β-hydroxybutyrate on the growth, metabolism and global histone H3 acetylation of spontaneous mouse mammary tumours: evidence of a β-hydroxybutyrate paradox in CANCER & METABOLISM
  • 2016-10-31 Assessment of early treatment response to neoadjuvant chemotherapy in breast cancer using non-mono-exponential diffusion models: a feasibility study comparing the baseline and mid-treatment MRI examinations in EUROPEAN RADIOLOGY
  • 2016-10-31 Response Monitoring with [18F]FLT PET and Diffusion-Weighted MRI After Cytotoxic 5-FU Treatment in an Experimental Rat Model for Colorectal Liver Metastases in MOLECULAR IMAGING AND BIOLOGY
  • 2016-10-26 The immunometabolite S-2-hydroxyglutarate regulates CD8+ T-lymphocyte fate in NATURE
  • 2016-10-11 Imaging biomarker roadmap for cancer studies in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2016-08-11 The relationship between endogenous thymidine concentrations and [18F]FLT uptake in a range of preclinical tumour models in EJNMMI RESEARCH
  • 2016-06-30 Response of Degarelix treatment in human prostate cancer monitored by HR-MAS 1H NMR spectroscopy in METABOLOMICS
  • 2015-08-11 Metabolomic changes during cellular transformation monitored by metabolite–metabolite correlation analysis and correlated with gene expression in METABOLOMICS
  • 2014-12-10 A PP1/PP2A phosphatase relay controls mitotic progression in NATURE
  • 2014-08-10 Artefacts in 1H NMR-based metabolomic studies on cell cultures in MAGNETIC RESONANCE MATERIALS IN PHYSICS, BIOLOGY AND MEDICINE
  • 2014-06-03 Dichloroacetate induces autophagy in colorectal cancer cells and tumours in BRITISH JOURNAL OF CANCER
  • 2014-05-29 Gemcitabine diphosphate choline is a major metabolite linked to the Kennedy pathway in pancreatic cancer models in vivo in BRITISH JOURNAL OF CANCER
  • 2014-02-19 Mass Spectral Enhanced Detection of Ubls Using SWATH Acquisition: MEDUSA—Simultaneous Quantification of SUMO and Ubiquitin-Derived Isopeptides in JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
  • 2013-01-30 Enhanced Detection of Ubiquitin Isopeptides Using Reductive Methylation in JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
  • 2012-12-17 Application of the MIDAS Approach for Analysis of Lysine Acetylation Sites in PROTEIN ACETYLATION
  • 2012-06-21 Fluorescence-guided surgical sampling of glioblastoma identifies phenotypically distinct tumour-initiating cell populations in the tumour mass and margin in BRITISH JOURNAL OF CANCER
  • 2012-05-23 Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy in BMC RESEARCH NOTES
  • 2011-05-25 Adaptation to HIF-1 deficiency by upregulation of the AMP/ATP ratio and phosphofructokinase activation in hepatomas in BMC CANCER
  • 2011-03-23 A novel method for quantification of gemcitabine and its metabolites 2′,2′-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC–MS/MS: comparison with 19F NMR spectroscopy in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2010-09-07 Can localised 19F magnetic resonance spectroscopy pharmacokinetics of 5FU in colorectal metastases predict clinical response? in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2010-08-26 Simultaneous analysis of relative protein expression levels across multiple samples using iTRAQ isobaric tags with 2D nano LC–MS/MS in NATURE PROTOCOLS
  • 2010-03-23 Ex-vivo HRMAS of adult brain tumours: metabolite quantification and assignment of tumour biomarkers in MOLECULAR CANCER
  • 2010-01-20 Tri-partite complex for axonal transport drug delivery achieves pharmacological effect in BMC NEUROSCIENCE
  • 2009-08-06 Apparent diffusion coefficient and vascular signal fraction measurements with magnetic resonance imaging: feasibility in metastatic ovarian cancer at 3 Tesla in EUROPEAN RADIOLOGY
  • 2009-05-14 A sensitive mass spectrometric method for hypothesis-driven detection of peptide post-translational modifications: multiple reaction monitoring-initiated detection and sequencing (MIDAS) in NATURE PROTOCOLS
  • 2009-02-17 Taurine: a potential marker of apoptosis in gliomas in BRITISH JOURNAL OF CANCER
  • 2008-07-03 Using Metabolomics to Monitor Anticancer Drugs in ONCOGENES MEET METABOLISM
  • 2007-08-07 Standard reporting requirements for biological samples in metabolomics experiments: mammalian/in vivo experiments in METABOLOMICS
  • 2007-08-01 The application of a hypothesis-driven strategy to the sensitive detection and location of acetylated lysine residues in JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
  • 2007-05-23 Glut-1 as a therapeutic target: increased chemoresistance and HIF-1-independent link with cell turnover is revealed through COMPARE analysis and metabolomic studies in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2006-01-01 Application of MRS in Cancer in Pre-clinical Models in MODERN MAGNETIC RESONANCE
  • 2005-10-25 Metabolic profiling of hypoxia-inducible factor-1β-deficient and wild type Hepa-1 cells: effects of hypoxia measured by 1H magnetic resonance spectroscopy in METABOLOMICS
  • 2005-06-27 PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP in ONCOGENE
  • 2005-05-03 The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations in BRITISH JOURNAL OF CANCER
  • 2005 The Effects of Tumour Blood Flow and Oxygenation Modifiers on Subcutaneous Tumours as Determined by NIRS in OXYGEN TRANSPORT TO TISSUE XXVI
  • 2005-01-01 Cancer Metabolic Phenotype in THE ONCOGENOMICS HANDBOOK
  • 2004-12-20 The C-neu mammary carcinoma in Oncomice; characterization and monitoring response to treatment with herceptin by magnetic resonance methods in MAGNETIC RESONANCE MATERIALS IN PHYSICS, BIOLOGY AND MEDICINE
  • 2004-10-05 Investigations in vivo of the effects of carbogen breathing on 5-fluorouracil pharmacokinetics and physiology of solid rodent tumours in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2003-05-13 Tumour dose response to the antivascular agent ZD6126 assessed by magnetic resonance imaging in BRITISH JOURNAL OF CANCER
  • 2003 Metabolic Profiling in Tumors by In Vivo and In Vitro NMR Spectroscopy in METABOLIC PROFILING: ITS ROLE IN BIOMARKER DISCOVERY AND GENE FUNCTION ANALYSIS
  • 2003 Issues in GRE & Se Magnetic Resonance Imaging to Probe Tumor Oxygenation in OXYGEN TRANSPORT TO TISSUE XXIV
  • 2002-08-20 Unsupervised Feature Extraction of in vivo Magnetic Resonance Spectra of Brain Tumours Using Independent Component Analysis in INTELLIGENT DATA ENGINEERING AND AUTOMATED LEARNING — IDEAL 2002
  • 2002-06-21 Classifier Combination for In Vivo Magnetic Resonance Spectra of Brain Tumours in MULTIPLE CLASSIFIER SYSTEMS
  • 2001-06-28 Visualisation of Multidimensional Data for Medical Decision Support in ARTIFICIAL INTELLIGENCE IN MEDICINE
  • 2001-04-23 Genetic prodrug activation therapy (GPAT) in two rat prostate models generates an immune bystander effect and can be monitored by magnetic resonance techniques in GENE THERAPY
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