Mark A Behlke

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Mark A



Publications in SciGraph latest 50 shown

  • 2019-01-28 Identification of preexisting adaptive immunity to Cas9 proteins in humans in NATURE MEDICINE
  • 2018-12 Single-Stranded Nucleic Acids Regulate TLR3/4/7 Activation through Interference with Clathrin-Mediated Endocytosis in SCIENTIFIC REPORTS
  • 2018-08 A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells in NATURE MEDICINE
  • 2018-03 A modular platform for targeted RNAi therapeutics in NATURE NANOTECHNOLOGY
  • 2017-12 Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins in GENOME BIOLOGY
  • 2017 Non-nucleotide Modification of Anti-miRNA Oligonucleotides in DRUG TARGET MIRNA
  • 2016 Quantification of Dicer Activity in Mammalian Cell Lysates Using a Non-radioactive Fluorescence Method in MICRORNA TECHNOLOGIES
  • 2014-03 Noninvasive imaging of Staphylococcus aureus infections with a nuclease-activated probe in NATURE MEDICINE
  • 2014-02 In vivo comparison of local versus systemic delivery of immunostimulating siRNA in HPV-driven tumours in IMMUNOLOGY AND CELL BIOLOGY
  • 2013 Synthetic Dicer-Substrate siRNAs as Triggers of RNA Interference in RNA INTERFERENCE FROM BIOLOGY TO THERAPEUTICS
  • 2012-02 siRNA-induced immunostimulation through TLR7 promotes antitumoral activity against HPV-driven tumors in vivo in IMMUNOLOGY AND CELL BIOLOGY
  • 2011-12 RNase H-dependent PCR (rhPCR): improved specificity and single nucleotide polymorphism detection using blocked cleavable primers in BMC BIOTECHNOLOGY
  • 2011-12 Chemical modification and design of anti-miRNA oligonucleotides in GENE THERAPY
  • 2010-09 A Direct Comparison of Anti-microRNA Oligonucleotide Potency in PHARMACEUTICAL RESEARCH
  • 2009-03 Gene silencing by synthetic U1 Adaptors in NATURE BIOTECHNOLOGY
  • 2008 Designing and Utilization of siRNAs Targeting RNA Binding Proteins in RNA-PROTEIN INTERACTION PROTOCOLS
  • 2006-09 Optimizing knockdown of gene expression using the Tri<i>FECT</i>a™ Dicer-substrate RNAi reagent system in NATURE METHODS
  • 2006-08 Rational design and in vitro and in vivo delivery of Dicer substrate siRNA in NATURE PROTOCOLS
  • 2006-05 A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells in NATURE BIOTECHNOLOGY
  • 2006-05 Stable expression of shRNAs in human CD34+ progenitor cells can avoid induction of interferon responses to siRNAs in vitro in NATURE BIOTECHNOLOGY
  • 2005-02 Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy in NATURE BIOTECHNOLOGY
  • 2005 Enhancing RNAi with Synthetic RNA Duplexes in NON-VIRAL GENE THERAPY
  • 1989-03 Identification of T-cell receptor Vβ deletion mutant mouse strain AU/ssJ (H-2q) which is resistant to collagen-induced arthritis in IMMUNOGENETICS
  • 1988 T-Cell Receptor Genes in THE T-CELL RECEPTORS
  • 1988-01 T-cell receptor VTβ genes in natural populations of mice in IMMUNOGENETICS
  • 1986-07 Alternative splicing of murine T-cell receptor β-chain transcripts in NATURE
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