James A Thomson

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James A



Publications in SciGraph latest 50 shown

  • 2019 A Machine-Learning-Based Drug Repurposing Approach Using Baseline Regularization. in COMPUTATIONAL METHODS FOR DRUG REPURPOSING
  • 2018-12 Trendy: segmented regression analysis of expression dynamics in high-throughput ordered profiling experiments in BMC BIOINFORMATICS
  • 2018-12 NOTCH signaling specifies arterial-type definitive hemogenic endothelium from human pluripotent stem cells in NATURE COMMUNICATIONS
  • 2018-04-05 Simultaneous reprogramming and gene editing of human fibroblasts in NATURE PROTOCOLS
  • 2017-06 SCnorm: robust normalization of single-cell RNA-seq data in NATURE METHODS
  • 2016-12 A statistical approach for identifying differential distributions in single-cell RNA-seq experiments in GENOME BIOLOGY
  • 2016-12 Single-cell RNA-seq reveals novel regulators of human embryonic stem cell differentiation to definitive endoderm in GENOME BIOLOGY
  • 2016-10-07 Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2 in NATURE COMMUNICATIONS
  • 2015-11 Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin in SCIENTIFIC REPORTS
  • 2015-10 Oscope identifies oscillatory genes in unsynchronized single-cell RNA-seq experiments in NATURE METHODS
  • 2015-08 A cost-effective RNA sequencing protocol for large-scale gene expression studies in SCIENTIFIC REPORTS
  • 2015-06 Human Vascular Tissue Models Formed from Human Induced Pluripotent Stem Cell Derived Endothelial Cells in STEM CELL REVIEWS AND REPORTS
  • 2015-03 Characterization and target identification of a DNA aptamer that labels pluripotent stem cells in CELL RESEARCH
  • 2015-02 Chromatin architecture reorganization during stem cell differentiation in NATURE
  • 2014-12 Evaluation of de novo transcriptome assemblies from RNA-Seq data in GENOME BIOLOGY
  • 2014-12 Direct induction of haematoendothelial programs in human pluripotent stem cells by transcriptional regulators in NATURE COMMUNICATIONS
  • 2014-10 Corrigendum: Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells in NATURE
  • 2014 Gene Targeting of Human Pluripotent Stem Cells by Homologous Recombination in GENE CORRECTION
  • 2013-12 A human pluripotent stem cell platform for assessing developmental neural toxicity screening in STEM CELL RESEARCH & THERAPY
  • 2012-11 Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions in NATURE PROTOCOLS
  • 2011-12 TF-Cluster: A pipeline for identifying functionally coordinated transcription factors via network decomposition of the shared coexpression connectivity matrix (SCCM) in BMC SYSTEMS BIOLOGY
  • 2011-10 Proteomic and phosphoproteomic comparison of human ES and iPS cells in NATURE METHODS
  • 2011-10 Dynamic chromatin states in human ES cells reveal potential regulatory sequences and genes involved in pluripotency in CELL RESEARCH
  • 2011-05 Chemically defined conditions for human iPSC derivation and culture in NATURE METHODS
  • 2011-03 Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells in NATURE
  • 2010-10 The NIH Roadmap Epigenomics Mapping Consortium in NATURE BIOTECHNOLOGY
  • 2009-11 Human DNA methylomes at base resolution show widespread epigenomic differences in NATURE
  • 2009-05 Histone modifications at human enhancers reflect global cell-type-specific gene expression in NATURE
  • 2009-04 Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming in NATURE BIOTECHNOLOGY
  • 2009-01-15 Induced pluripotent stem cells from a spinal muscular atrophy patient in NATURE
  • 2008-12 Optical mapping discerns genome wide DNA methylation profiles in BMC MOLECULAR BIOLOGY
  • 2007-01 Nanog and transcriptional networks in embryonic stem cell pluripotency in CELL RESEARCH
  • 2007 Defined Culture Media for Human Embryonic Stem Cells in HUMAN CELL CULTURE
  • 2006-10 Erratum: Feeder-independent culture of human embryonic stem cells in NATURE METHODS
  • 2006-08 Feeder-independent culture of human embryonic stem cells in NATURE METHODS
  • 2006-02 Derivation of human embryonic stem cells in defined conditions in NATURE BIOTECHNOLOGY
  • 2005-03 Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells in NATURE METHODS
  • 2004-01 Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells in NATURE BIOTECHNOLOGY
  • 2003-03 Homologous recombination in human embryonic stem cells in NATURE BIOTECHNOLOGY
  • 2003 Protocols for the Isolation and Maintenance of Human Embryonic Stem Cells in HUMAN EMBRYONIC STEM CELLS
  • 2002-12 BMP4 initiates human embryonic stem cell differentiation to trophoblast in NATURE BIOTECHNOLOGY
  • 2001-12 In vitro differentiation of transplantable neural precursors from human embryonic stem cells in NATURE BIOTECHNOLOGY
  • 2001-01-15 Isolation and Maintenance of Primate Embryonic Stem Cells in GENE KNOCKOUT PROTOCOLS
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