Jonathan D Powell

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Jonathan D



Publications in SciGraph latest 50 shown

  • 2018-12 A phase II study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcomas in CLINICAL SARCOMA RESEARCH
  • 2018-08 Inhibition of the adenosine A2a receptor modulates expression of T cell coinhibitory receptors and improves effector function for enhanced checkpoint blockade and ACT in murine cancer models in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2017-01-27 mTORC2 signalling regulates M2 macrophage differentiation in response to helminth infection and adaptive thermogenesis in NATURE COMMUNICATIONS
  • 2016-06 Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8+ T cell differentiation in NATURE IMMUNOLOGY
  • 2015-12 The PTEN pathway in Tregs functions as a critical driver of the immunosuppressive tumor microenvironment and tolerance to apoptotic cells in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2014-09-18 Retraction: Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways in NATURE IMMUNOLOGY
  • 2014-07 Integrating canonical and metabolic signalling programmes in the regulation of T cell responses in NATURE REVIEWS IMMUNOLOGY
  • 2014-05 The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex in NATURE IMMUNOLOGY
  • 2014 Mammalian Target of Rapamycin (mTOR) in ENCYCLOPEDIA OF MEDICAL IMMUNOLOGY
  • 2013-12 Hyaluronan fragments induce IFNβ via a novel TLR4-TRIF-TBK1-IRF3-dependent pathway in JOURNAL OF INFLAMMATION
  • 2013-10 Sirolimus and post transplant Cy synergistically maintain mixed chimerism in a mismatched murine model in BONE MARROW TRANSPLANTATION
  • 2013-06 Natural and inducible TH17 cells are regulated differently by Akt and mTOR pathways in NATURE IMMUNOLOGY
  • 2012-06 Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2012 Exploring Functional In Vivo Consequences of the Selective Genetic Ablation of mTOR Signaling in T Helper Lymphocytes in MTOR
  • 2011-04 The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2 in NATURE IMMUNOLOGY
  • 2010-07 Genetic and biochemical regulation of CD4 T cell effector differentiation: insights from examination of T cell clonal anergy in IMMUNOLOGIC RESEARCH
  • 2010-04 Quieting T cells with Slfn2 in NATURE IMMUNOLOGY
  • 2009-05-28 Adenosine Receptors and Cancer in ADENOSINE RECEPTORS IN HEALTH AND DISEASE
  • 2009-03 Salvage transplantation for allograft failure using fludarabine and alemtuzumab as conditioning regimen in BONE MARROW TRANSPLANTATION
  • 2008-12 Anti-oxidant inhibition of hyaluronan fragment-induced inflammatory gene expression in JOURNAL OF INFLAMMATION
  • 2005-07 Erratum: Egr-2 and Egr-3 are negative regulators of T cell activation in NATURE IMMUNOLOGY
  • 2005-05 Egr-2 and Egr-3 are negative regulators of T cell activation in NATURE IMMUNOLOGY
  • 2005-04 Threat matrix in IMMUNOLOGIC RESEARCH
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