David T W Jones

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David T W



Publications in SciGraph latest 50 shown

  • 2019-03 Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1 in ACTA NEUROPATHOLOGICA
  • 2018-12 Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p in ACTA NEUROPATHOLOGICA
  • 2018-12 Recurrent homozygous deletion of DROSHA and microduplication of PDE4DIP in pineoblastoma in NATURE COMMUNICATIONS
  • 2018-12 Transcriptomic and epigenetic profiling of ‘diffuse midline gliomas, H3 K27M-mutant’ discriminate two subgroups based on the type of histone H3 mutated and not supratentorial or infratentorial location in ACTA NEUROPATHOLOGICA COMMUNICATIONS
  • 2018-12 Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants in NATURE COMMUNICATIONS
  • 2018-12 Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors in NATURE COMMUNICATIONS
  • 2018-12 A novel cloning strategy for one-step assembly of multiplex CRISPR vectors in SCIENTIFIC REPORTS
  • 2018-11 A biobank of patient-derived pediatric brain tumor models in NATURE MEDICINE
  • 2018-10 Duplications of KIAA1549 and BRAF screening by Droplet Digital PCR from formalin-fixed paraffin-embedded DNA is an accurate alternative for KIAA1549-BRAF fusion detection in pilocytic astrocytomas in MODERN PATHOLOGY
  • 2018-10 Methylome analysis and whole-exome sequencing reveal that brain tumors associated with encephalocraniocutaneous lipomatosis are midline pilocytic astrocytomas in ACTA NEUROPATHOLOGICA
  • 2018-09-30 Modern Principles of CNS Tumor Classification in BRAIN TUMORS IN CHILDREN
  • 2018-08 Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas in ACTA NEUROPATHOLOGICA
  • 2018-08 Molecular characterization of medulloblastomas with extensive nodularity (MBEN) in ACTA NEUROPATHOLOGICA
  • 2018-08 Myxoid glioneuronal tumor of the septum pellucidum and lateral ventricle is defined by a recurrent PDGFRA p.K385 mutation and DNT-like methylation profile in ACTA NEUROPATHOLOGICA
  • 2018-08 Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience in ACTA NEUROPATHOLOGICA
  • 2018-08 Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information in MODERN PATHOLOGY
  • 2018-08 Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations in ACTA NEUROPATHOLOGICA
  • 2018-08 DNA methylation-based reclassification of olfactory neuroblastoma in ACTA NEUROPATHOLOGICA
  • 2018-08 Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations in ACTA NEUROPATHOLOGICA
  • 2018-08 Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features in ACTA NEUROPATHOLOGICA
  • 2018-08 FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma in ACTA NEUROPATHOLOGICA
  • 2018-07 Novel, improved grading system(s) for IDH-mutant astrocytic gliomas in ACTA NEUROPATHOLOGICA
  • 2018-07 Author Correction: The landscape of genomic alterations across childhood cancers in NATURE
  • 2018-05 Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target in ACTA NEUROPATHOLOGICA
  • 2018-03 DNA methylation-based classification of central nervous system tumours in NATURE
  • 2018-03 The landscape of genomic alterations across childhood cancers in NATURE
  • 2018-01 Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling in NATURE
  • 2017-12 Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases in CLINICAL SARCOMA RESEARCH
  • 2017-12 Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery in ACTA NEUROPATHOLOGICA COMMUNICATIONS
  • 2017-12 DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma in ACTA NEUROPATHOLOGICA
  • 2017-10 Genomic profiling of Acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis in LEUKEMIA
  • 2017-09 H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers in ACTA NEUROPATHOLOGICA
  • 2017-07 The whole-genome landscape of medulloblastoma subtypes in NATURE
  • 2017-07 Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature in ACTA NEUROPATHOLOGICA
  • 2017-05 Spatial heterogeneity in medulloblastoma in NATURE GENETICS
  • 2017-04 Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease in JOURNAL OF NEURO-ONCOLOGY
  • 2017-03-20 Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme in NATURE COMMUNICATIONS
  • 2017-03 Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic alterations involving the MAP kinase pathway in ACTA NEUROPATHOLOGICA
  • 2017-03 Global epigenetic profiling identifies methylation subgroups associated with recurrence-free survival in meningioma in ACTA NEUROPATHOLOGICA
  • 2017-02 Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas in ACTA NEUROPATHOLOGICA
  • 2016-12 Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles in ACTA NEUROPATHOLOGICA COMMUNICATIONS
  • 2016-11 Recurrent MET fusion genes represent a drug target in pediatric glioblastoma in NATURE MEDICINE
  • 2016-10 Evidence of H3 K27M mutations in posterior fossa ependymomas in ACTA NEUROPATHOLOGICA
  • 2016-09 EpCAM (CD326) is differentially expressed in craniopharyngioma subtypes and Rathke’s cleft cysts in SCIENTIFIC REPORTS
  • 2016-08 Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma in JOURNAL OF NEURO-ONCOLOGY
  • 2016-07 Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis in ACTA NEUROPATHOLOGICA
  • 2016-06 Methylation-based classification of benign and malignant peripheral nerve sheath tumors in ACTA NEUROPATHOLOGICA
  • 2016-06 Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets in ACTA NEUROPATHOLOGICA
  • 2016-05 No correlation between NF1 mutation position and risk of optic pathway glioma in 77 unrelated NF1 patients in HUMAN GENETICS
  • 2016-02 Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity in ACTA NEUROPATHOLOGICA
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