Jennifer A Doudna

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Jennifer A



Publications in SciGraph latest 50 shown

  • 2019-01 CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions in NATURE PROTOCOLS
  • 2017-12 A thermostable Cas9 with increased lifetime in human plasma in NATURE COMMUNICATIONS
  • 2017-12 CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing in NATURE COMMUNICATIONS
  • 2017-11 Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair in NATURE BIOMEDICAL ENGINEERING
  • 2017-10-04 The chemistry of Cas9 and its CRISPR colleagues in NATURE REVIEWS CHEMISTRY
  • 2017-10 Guide-bound structures of an RNA-targeting A-cleaving CRISPR–Cas13a enzyme in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2017-10 Enhanced proofreading governs CRISPR–Cas9 targeting accuracy in NATURE
  • 2017-04 RNA-based recognition and targeting: sowing the seeds of specificity in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2017-02-13 Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes in NATURE BIOTECHNOLOGY
  • 2017-02 Cornerstones of CRISPR-Cas in drug discovery and therapy in NATURE REVIEWS DRUG DISCOVERY
  • 2016-12-22 New CRISPR–Cas systems from uncultivated microbes in NATURE
  • 2016-12 ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing in NATURE METHODS
  • 2016-10 Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection in NATURE
  • 2016-10 Protecting genome integrity during CRISPR immune adaptation in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2016-09-14 Real-time observation of DNA recognition and rejection by the RNA-guided endonuclease Cas9 in NATURE COMMUNICATIONS
  • 2016-09 Applications of CRISPR technologies in research and beyond in NATURE BIOTECHNOLOGY
  • 2016-08 eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation in NATURE
  • 2016-07-07 Foreign DNA capture during CRISPR–Cas adaptive immunity in NATURE
  • 2016-06 Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch in NATURE BIOTECHNOLOGY
  • 2015-12-22 Genome-editing revolution: My whirlwind year with CRISPR in NATURE
  • 2015-12-02 Perspective: Embryo editing needs scrutiny in NATURE
  • 2015-12 Genome editing: the end of the beginning in GENOME BIOLOGY
  • 2015-11 Foreign DNA capture during CRISPR–Cas adaptive immunity in NATURE
  • 2015-11 Conformational control of DNA target cleavage by CRISPR–Cas9 in NATURE
  • 2015-03 Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity in NATURE
  • 2014-12 Programmable RNA recognition and cleavage by CRISPR/Cas9 in NATURE
  • 2014-07 Insights into RNA structure and function from genome-wide studies in NATURE REVIEWS GENETICS
  • 2014-06 Cas1–Cas2 complex formation mediates spacer acquisition during CRISPR–Cas adaptive immunity in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2014-03 DNA interrogation by the CRISPR RNA-guided endonuclease Cas9 in NATURE
  • 2013-10 Activating silent Argonautes in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2013-09 High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity in NATURE BIOTECHNOLOGY
  • 2013-07 Activating silent Argonautes in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2013-06 Substrate-specific structural rearrangements of human Dicer in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2013-03 Biotechnology: Rewriting a genome in NATURE
  • 2012-10 RNA processing enables predictable programming of gene expression in NATURE BIOTECHNOLOGY
  • 2012-02 RNA-guided genetic silencing systems in bacteria and archaea in NATURE
  • 2011-09 Structures of the RNA-guided surveillance complex from a bacterial immune system in NATURE
  • 2011-06 An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3 in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2011-05 Structural basis for CRISPR RNA-guided DNA recognition by Cascade in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2010-02 Structural insights into the human GW182-PABC interaction in microRNA-mediated deadenylation in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2009-11 Structural insights into RNA processing by the human RISC-loading complex in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2009-04 The pathway of hepatitis C virus mRNA recruitment to the human ribosome in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2009-01-22 A three-dimensional view of the molecular machinery of RNA interference in NATURE
  • 2007-10 Structural determinants of RNA recognition and cleavage by Dicer in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2007-01 Structural and mechanistic insights into hepatitis C viral translation initiation in NATURE REVIEWS MICROBIOLOGY
  • 2005-12 RNA-mediated interaction between the peptide-binding and GTPase domains of the signal recognition particle in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2005-11 Chemical biology at the crossroads of molecular structure and mechanism in NATURE CHEMICAL BIOLOGY
  • 2005-05 Ribozyme catalysis: not different, just worse in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2004-05 A conformational switch controls hepatitis delta virus ribozyme catalysis in NATURE
  • 2002-07 The chemical repertoire of natural ribozymes in NATURE
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