James Arthos

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Publications in SciGraph latest 50 shown

  • 2018-12 HIV-1 targets L-selectin for adhesion and induces its shedding for viral release in NATURE COMMUNICATIONS
  • 2018-12 Common helical V1V2 conformations of HIV-1 Envelope expose the α4β7 binding site on intact virions in NATURE COMMUNICATIONS
  • 2018-09 MAdCAM costimulation through Integrin-α4β7 promotes HIV replication in MUCOSAL IMMUNOLOGY
  • 2018-05 Early treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infection in MUCOSAL IMMUNOLOGY
  • 2018-04 The Role of Integrin α4β7 in HIV Pathogenesis and Treatment in CURRENT HIV/AIDS REPORTS
  • 2016-01 Identification of preferential CD4+ T-cell targets for HIV infection in the cervix in MUCOSAL IMMUNOLOGY
  • 2015-07 Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2014-12 Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection in NATURE MEDICINE
  • 2014 Virion Attachment and Entry: HIV gp120 Env Biotinylation, gp120 Env, or Integrin Ligand-Binding Assay in HUMAN RETROVIRUSES
  • 2013-12 The HIV-1 envelope protein gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression in NATURE IMMUNOLOGY
  • 2011-12 Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 in NATURE
  • 2011-12 HIV-1 envelope, integrins and co-receptor use in mucosal transmission of HIV in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2009-10 P07-01. The gut mucosal homing receptor integrin α4β7 forms a complex with CD4 and defines a T cell subset that is highly susceptible to infection by HIV-1 in RETROVIROLOGY
  • 2009-09 Post-entry events of efficient R5 vs. inefficient X4 HIV-1 replication in primary CD4+T lymphocytes, a transcriptome analysis in RETROVIROLOGY
  • 2008-03 HIV-1 envelope protein binds to and signals through integrin α4β7, the gut mucosal homing receptor for peripheral T cells in NATURE IMMUNOLOGY
  • 2007-02 Structural definition of a conserved neutralization epitope on HIV-1 gp120 in NATURE
  • 2006-12 Design clues from functional constraints and broadly neutralizing antibodies in RETROVIROLOGY
  • 2005-05 Cocaine increases human immunodeficiency virus type 1 neuroinvasion through remodeling brain microvascular endothelial cells in JOURNAL OF NEUROVIROLOGY
  • 2004-12 HAART drugs induce mitochondrial damage and intercellular gaps and gp 120 causes apoptosis in CARDIOVASCULAR TOXICOLOGY
  • 2004-06 HIV-1 induces cardiomyopathy by cardiomyocyte invasion and gp120, tat, and cytokine apoptotic signaling in CARDIOVASCULAR TOXICOLOGY
  • 2002-12 HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites in NATURE
  • 1999-09-23 Antigen Engineering in DNA Immunization in DNA VACCINES
  • 1997-10 Macrophage-tropic HIV and SIV envelope proteins induce a signal through the CCR5 chemokine receptor in NATURE
  • 1996-11 CD4-dependent, antibody-sensitive interactions between HIV-1 and its co-receptor CCR-5 in NATURE
  • 1990-11 Crystal structure of an HIV-binding recombinant fragment of human CD4 in NATURE
  • 1988-01 soluble form of CD4 (T4) protein inhibits AIDS virus infection in NATURE
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