Richard Simon


Ontology type: schema:Person     


Person Info

NAME

Richard

SURNAME

Simon

Publications in SciGraph latest 50 shown

  • 2018-12 Correlation of gene expression and associated mutation profiles of APOBEC3A, APOBEC3B, REV1, UNG, and FHIT with chemosensitivity of cancer cell lines to drug treatment in HUMAN GENOMICS
  • 2017-12 A computational study of the inhibition mechanisms of P-glycoprotein mediated paclitaxel efflux by kinase inhibitors in BMC SYSTEMS BIOLOGY
  • 2016-12 Concerted changes in transcriptional regulation of genes involved in DNA methylation, demethylation, and folate-mediated one-carbon metabolism pathways in the NCI-60 cancer cell line panel in response to cancer drug treatment in CLINICAL EPIGENETICS
  • 2014-12 Using single cell sequencing data to model the evolutionary history of a tumor in BMC BIOINFORMATICS
  • 2013-12 Criteria for the use of omics-based predictors in clinical trials: explanation and elaboration in BMC MEDICINE
  • 2013-12 Using passenger mutations to estimate the timing of driver mutations and identify mutator alterations in BMC BIOINFORMATICS
  • 2013-10 Criteria for the use of omics-based predictors in clinical trials in NATURE
  • 2013-10 CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2 in BRITISH JOURNAL OF CANCER
  • 2013-10 Considerations for the successful co-development of targeted cancer therapies and companion diagnostics in NATURE REVIEWS DRUG DISCOVERY
  • 2013-05 Implementing personalized cancer genomics in clinical trials in NATURE REVIEWS DRUG DISCOVERY
  • 2013 T Cell Epitope, Prediction with Peptide Libraries in ENCYCLOPEDIA OF SYSTEMS BIOLOGY
  • 2013 Oncology Clinical Trials in the Genomic Era in PROCEEDINGS OF THE FOURTH SEATTLE SYMPOSIUM IN BIOSTATISTICS: CLINICAL TRIALS
  • 2012-12 IRF5 gene polymorphisms in melanoma in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2011-12 Optimally splitting cases for training and testing high dimensional classifiers in BMC MEDICAL GENOMICS
  • 2011-12 Microarray-based cancer prediction using single genes in BMC BIOINFORMATICS
  • 2011-12 Construct and Compare Gene Coexpression Networks with DAPfinder and DAPview in BMC BIOINFORMATICS
  • 2010-12 Gene expression deconvolution in clinical samples in GENOME MEDICINE
  • 2010-06 What should physicians look for in evaluating prognostic gene-expression signatures? in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2009 The Statistical Design and Interpretation of Microarray Experiments in BIOINFORMATICS IN CANCER AND CANCER THERAPY
  • 2008 Identification of Pharmacogenomic Biomarker Classifiers in Cancer Drug Development in GENOMICS AND PHARMACOGENOMICS IN ANTICANCER DRUG DEVELOPMENT AND CLINICAL RESPONSE
  • 2007 Artificial Intelligence Methods for Predicting T-Cell Epitopes in IMMUNOINFORMATICS
  • 2006-12 Bias in error estimation when using cross-validation for model selection in BMC BIOINFORMATICS
  • 2006-08 The Norton–Simon hypothesis: designing more effective and less toxic chemotherapeutic regimens in NATURE REVIEWS CLINICAL ONCOLOGY
  • 2006-05 Use of genomic signatures in therapeutics development in oncology and other diseases in THE PHARMACOGENOMICS JOURNAL
  • 2006-03 Designing prospective clinical pharmacogenomic (PG) trials: meeting report on drug development strategies to enhance therapeutic decision making in THE PHARMACOGENOMICS JOURNAL
  • 2006 Charakterisierung der lymphogenen Metastasierung von Kolonkarzinomen mittels Genexpressionsanalysen in CHIRURGISCHES FORUM 2006
  • 2005-12 An adaptive method for cDNA microarray normalization in BMC BIOINFORMATICS
  • 2005 Bioinformatics and Whole-Genome Technologies in CANCER CHEMOPREVENTION
  • 2004-12 Iterative class discovery and feature selection using Minimal Spanning Trees in BMC BIOINFORMATICS
  • 2004 Vorhersage des Ansprechens von Rektumkarzinomen auf eine neoadjuvante Radiochemotherapie mit Hilfe von Genexpressionsanalysen in CHIRURGISCHES FORUM 2004
  • 2003-06 A strategy for detection of known and unknown SNP using a minimum number of oligonucleotides applicable in the clinical settings in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2003-04 Predicting hepatitis B virus–positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning in NATURE MEDICINE
  • 2003 Image Analysis in DESIGN AND ANALYSIS OF DNA MICROARRAY INVESTIGATIONS
  • 2003 Design of DNA Microarray Experiments in DESIGN AND ANALYSIS OF DNA MICROARRAY INVESTIGATIONS
  • 2003 Introduction in DESIGN AND ANALYSIS OF DNA MICROARRAY INVESTIGATIONS
  • 2003 Class Comparison in DESIGN AND ANALYSIS OF DNA MICROARRAY INVESTIGATIONS
  • 2003 Quality Control in DESIGN AND ANALYSIS OF DNA MICROARRAY INVESTIGATIONS
  • 2003 Class Prediction in DESIGN AND ANALYSIS OF DNA MICROARRAY INVESTIGATIONS
  • 2003 DNA Microarray Technology in DESIGN AND ANALYSIS OF DNA MICROARRAY INVESTIGATIONS
  • 2003 Array Normalization in DESIGN AND ANALYSIS OF DNA MICROARRAY INVESTIGATIONS
  • 2003 Class Discovery in DESIGN AND ANALYSIS OF DNA MICROARRAY INVESTIGATIONS
  • 2002-04 Identifying pre-post chemotherapy differences in gene expression in breast tumours: a statistical method appropriate for this aim in BRITISH JOURNAL OF CANCER
  • 2001 The Integration of Positional Scanning Libraries with Bioinformatics and Proteomics in PEPTIDES: THE WAVE OF THE FUTURE
  • 1999-12 Identification of candidate T-cell epitopes and molecular mimics in chronic Lyme disease in NATURE MEDICINE
  • 1999-11 Characterization of cDNA microarrays fabricated using thermal ink jets in NATURE GENETICS
  • 1999-11 A bioinformatics tool to mine sequences for microarray studies of mouse models of oncogenesis in NATURE GENETICS
  • 1998-09 Data management and analysis for gene expression arrays in NATURE GENETICS
  • 1998-05 Evidence that Childhood Acute Lymphoblastic Leukemia is Associated with an Infectious Agent Linked to Hygiene Conditions in CANCER CAUSES & CONTROL
  • 1995 Recent developments in the design of phase II clinical trials in RECENT ADVANCES IN CLINICAL TRIAL DESIGN AND ANALYSIS
  • 1995 A Bayesian model for evaluating specificity of treatment effects in clinical trials in RECENT ADVANCES IN CLINICAL TRIAL DESIGN AND ANALYSIS
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