Christine A Orengo

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Christine A



Publications in SciGraph latest 50 shown

  • 2019-12 A CATH domain functional family based approach to identify putative cancer driver genes and driver mutations in SCIENTIFIC REPORTS
  • 2018-09-27 Exploring Enzyme Evolution from Changes in Sequence, Structure, and Function in COMPUTATIONAL METHODS IN PROTEIN EVOLUTION
  • 2017-12 Genome-wide RNA-Sequencing analysis identifies a distinct fibrosis gene signature in the conjunctiva after glaucoma surgery in SCIENTIFIC REPORTS
  • 2017-12 Structural and Functional View of Polypharmacology in SCIENTIFIC REPORTS
  • 2017 CATH-Gene3D: Generation of the Resource and Its Use in Obtaining Structural and Functional Annotations for Protein Sequences in PROTEIN BIOINFORMATICS
  • 2017 The Classification of Protein Domains in BIOINFORMATICS
  • 2017 Function Diversity Within Folds and Superfamilies in FROM PROTEIN STRUCTURE TO FUNCTION WITH BIOINFORMATICS
  • 2016-12 An expanded evaluation of protein function prediction methods shows an improvement in accuracy in GENOME BIOLOGY
  • 2015-12 Identifying and characterising key alternative splicing events in Drosophila development in BMC GENOMICS
  • 2015-12 Co-Expression Network Models Suggest that Stress Increases Tolerance to Mutations in SCIENTIFIC REPORTS
  • 2014-12 Crystal structures of the human Dysferlin inner DysF domain in BMC STRUCTURAL BIOLOGY
  • 2014-12 A comparison of RNA-seq and exon arrays for whole genome transcription profiling of the L5 spinal nerve transection model of neuropathic pain in the rat in MOLECULAR PAIN
  • 2014 Target Selection for Structural Genomics of Infectious Diseases in STRUCTURAL GENOMICS AND DRUG DISCOVERY
  • 2013-03 A large-scale evaluation of computational protein function prediction in NATURE METHODS
  • 2013-02 Protein function prediction using domain families in BMC BIOINFORMATICS
  • 2013 Domain Structure Classifications in ENCYCLOPEDIA OF BIOPHYSICS
  • 2012-12 ReadqPCR and NormqPCR: R packages for the reading, quality checking and normalisation of RT-qPCR quantification cycle (Cq) data in BMC GENOMICS
  • 2011-12 1,000 structures and more from the MCSG in BMC STRUCTURAL BIOLOGY
  • 2011-12 Characterization of pathogenic germline mutations in human Protein Kinases in BMC BIOINFORMATICS
  • 2011-03-29 Exploiting Protein Structures to Predict Protein Functions in PROTEIN FUNCTION PREDICTION FOR OMICS ERA
  • 2010-12 Comparative evolutionary analysis of protein complexes in E. coli and yeast in BMC GENOMICS
  • 2009-08 An integrated approach to the interpretation of Single Amino Acid Polymorphisms within the framework of CATH and Gene3D in BMC BIOINFORMATICS
  • 2009-04 Structural genomics is the largest contributor of novel structural leverage in JOURNAL OF STRUCTURAL AND FUNCTIONAL GENOMICS
  • 2009-02 Protein function annotation by homology-based inference in GENOME BIOLOGY
  • 2009 Function Diversity Within Folds and Superfamilies in FROM PROTEIN STRUCTURE TO FUNCTION WITH BIOINFORMATICS
  • 2008-08-22 Assessing functional novelty of PSI structures via structure-function analysis of large and diverse superfamilies in NATURE PRECEDINGS
  • 2008 Structure to function in MODERN GENOME ANNOTATION
  • 2008 Modern genome annotation: the BioSapiens network in MODERN GENOME ANNOTATION
  • 2008 Target Selection for Structural Genomics: An Overview in STRUCTURAL PROTEOMICS
  • 2008 The Classification of Protein Domains in BIOINFORMATICS
  • 2007-12 Establishing a major cause of discrepancy in the calibration of Affymetrix GeneChips in BMC BIOINFORMATICS
  • 2007-12 Predicting protein function from sequence and structure in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2007-12 Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint in BMC BIOINFORMATICS
  • 2007 Gene3D and Understanding Proteome Evolution in STRUCTURAL APPROACHES TO SEQUENCE EVOLUTION
  • 2006-12 Microarray analysis after RNA amplification can detect pronounced differences in gene expression using limma in BMC GENOMICS
  • 2006-10 Protein Superfamily Evolution and the Last Universal Common Ancestor (LUCA) in JOURNAL OF MOLECULAR EVOLUTION
  • 2006 Improved Robustness in Time Series Analysis of Gene Expression Data by Polynomial Model Based Clustering in COMPUTATIONAL LIFE SCIENCES II
  • 2005 Cluster Based Integration of Heterogeneous Biological Databases Using the AutoMed Toolkit in DATA INTEGRATION IN THE LIFE SCIENCES
  • 2004-10 Consensus clustering and functional interpretation of gene-expression data in GENOME BIOLOGY
  • 2004-05 Progress towards mapping the universe of protein folds in GENOME BIOLOGY
  • 2001 A framework for Modelling Short, High-Dimensional Multivariate Time Series: Preliminary Results in Virus Gene Expression Data Analysis in ADVANCES IN INTELLIGENT DATA ANALYSIS
  • 2000-11-01 From structure to function: Approaches and limitations in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 1994-12 Protein superfamilles and domain superfolds in NATURE
  • 1993-09 Shared structural motif in proteins in NATURE
  • 1993-03 Recurrence of a binding motif? in NATURE
  • 1992 A Review of Methods for Protein Structure Comparison in PATTERNS IN PROTEIN SEQUENCE AND STRUCTURE
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