John A Todd

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John A



Publications in SciGraph latest 50 shown

  • 2018-12 The plasma biomarker soluble SIGLEC-1 is associated with the type I interferon transcriptional signature, ethnic background and renal disease in systemic lupus erythematosus in ARTHRITIS RESEARCH & THERAPY
  • 2018-10 Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes in NATURE GENETICS
  • 2018-07 Approaches and advances in the genetic causes of autoimmune disease and their implications in NATURE IMMUNOLOGY
  • 2018-07 Evidence that UBASH3 is a causal gene for type 1 diabetes in EUROPEAN JOURNAL OF HUMAN GENETICS
  • 2018-06 Genomic atlas of the human plasma proteome in NATURE
  • 2018-01 The chromosome 6q22.33 region is associated with age at diagnosis of type 1 diabetes and disease risk in those diagnosed under 5 years of age in DIABETOLOGIA
  • 2017-12 Chromosome contacts in activated T cells identify autoimmune disease candidate genes in GENOME BIOLOGY
  • 2017-07 Ultra-sensitive troponin I is an independent predictor of incident coronary heart disease in the general population in EUROPEAN JOURNAL OF EPIDEMIOLOGY
  • 2017-02 Factors independently associated with cardiac troponin I levels in young and healthy adults from the general population in CLINICAL RESEARCH IN CARDIOLOGY
  • 2017-02 A method for identifying genetic heterogeneity within phenotypically defined disease subgroups in NATURE GENETICS
  • 2017-01 Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity in DIABETOLOGIA
  • 2016-05 Intolerable secretion and diabetes in tolerant transgenic mice, revisited in NATURE GENETICS
  • 2015-12 Simulation work in adaptive dose-finding designs to identify dose-intervals that achieve targets in multiple endpoints in TRIALS
  • 2015-12 Widespread seasonal gene expression reveals annual differences in human immunity and physiology in NATURE COMMUNICATIONS
  • 2015-12 Effective recruitment of participants to a phase I study using the internet and publicity releases through charities and patient organisations: analysis of the adaptive study of IL-2 dose on regulatory T cells in type 1 diabetes (DILT1D) in TRIALS
  • 2015-08 Corrigendum: Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls in NATURE GENETICS
  • 2015-08 Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk in NATURE GENETICS
  • 2015-07 Statistical colocalization of genetic risk variants for related autoimmune diseases in the context of common controls in NATURE GENETICS
  • 2015-04 IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients in DIABETOLOGIA
  • 2015-04 Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers in NATURE GENETICS
  • 2015-02 Increased Plasma IL-17F Levels in Rheumatoid Arthritis Patients Are Responsive to Methotrexate, Anti-TNF, and T Cell Costimulatory Modulation in INFLAMMATION
  • 2014-12 A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples in BMC GENOMICS
  • 2014-06 The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2014-02 Plasma concentrations of soluble IL-2 receptor α (CD25) are increased in type 1 diabetes and associated with reduced C-peptide levels in young patients in DIABETOLOGIA
  • 2013-11 Adaptive dose-finding designs to identify multiple doses that achieve multiple response targets in TRIALS
  • 2013-10 The IL23R A/Gln381 Allele Promotes IL-23 Unresponsiveness in Human Memory T-Helper 17 Cells and Impairs Th17 Responses in Psoriasis Patients in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2013-06 Negligible impact of rare autoimmune-locus coding-region variants on missing heritability in NATURE
  • 2012-12-16 Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer in NATURE
  • 2012-12 Bayesian refinement of association signals for 14 loci in 3 common diseases in NATURE GENETICS
  • 2012-07 Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases in DIABETOLOGIA
  • 2012-04 Confirmation of novel type 1 diabetes risk loci in families in DIABETOLOGIA
  • 2012-01 Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry in NATURE GENETICS
  • 2011-12 Evidence of association with type 1 diabetes in the SLC11A1 gene region in BMC MEDICAL GENETICS
  • 2011-12 Antibodies against insulin measured by electrochemiluminescence predicts insulitis severity and disease onset in non-obese diabetic mice and can distinguish human type 1 diabetes status in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2010-10 Ten years of genetics and genomics: what have we achieved and where are we heading? in NATURE REVIEWS GENETICS
  • 2010-09 A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk in NATURE
  • 2010-04 Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls in NATURE
  • 2010-02 Multiplexed immunophenotyping of human antigen-presenting cells in whole blood by polychromatic flow cytometry in NATURE PROTOCOLS
  • 2010-01 The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes in NATURE GENETICS
  • 2009-12 Follow-up of 1715 SNPs from the Wellcome Trust Case Control Consortium genome-wide association study in type I diabetes families in GENES & IMMUNITY
  • 2009-12 Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families in GENES & IMMUNITY
  • 2009-12 Analysis of 55 autoimmune disease and type II diabetes loci: further confirmation of chromosomes 4q27, 12q13.2 and 12q24.13 as type I diabetes loci, and support for a new locus, 12q13.3–q14.1 in GENES & IMMUNITY
  • 2009-12 Overview of the Type I Diabetes Genetics Consortium in GENES & IMMUNITY
  • 2009-12 Contrasting genetic association of IL2RAwith SLE and ANCA – associated vasculitis in BMC MEDICAL GENETICS
  • 2009-12 Association analyses of the vitamin D receptor gene in 1654 families with type I diabetes in GENES & IMMUNITY
  • 2009-12 Current status and the future for the genetics of type I diabetes in GENES & IMMUNITY
  • 2009-10 Experimental aspects of copy number variant assays at CCL3L1 in NATURE MEDICINE
  • 2009-10 No association of multiple type 2 diabetes loci with type 1 diabetes in DIABETOLOGIA
  • 2009-09 Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource in NATURE GENETICS
  • 2009-06 Ambulatory blood pressure measurements are related to albumin excretion and are predictive for risk of microalbuminuria in young people with type 1 diabetes in DIABETOLOGIA
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