David L Vaux

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David L



Publications in SciGraph latest 50 shown

  • 2018-01 Viewing BCL2 and cell death control from an evolutionary perspective in CELL DEATH & DIFFERENTIATION
  • 2017-12-11 Autophagy induced during apoptosis degrades mitochondria and inhibits type I interferon secretion in CELL DEATH & DIFFERENTIATION
  • 2016-11 Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion in CELL DEATH & DIFFERENTIATION
  • 2016-07 Proceedings of the 4th World Conference on Research Integrity in RESEARCH INTEGRITY AND PEER REVIEW
  • 2016-07 Evolutionary divergence of the necroptosis effector MLKL in CELL DEATH & DIFFERENTIATION
  • 2016-02 Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies in NATURE REVIEWS CANCER
  • 2016 Scientific Misconduct: Falsification, Fabrication, and Misappropriation of Credit in HANDBOOK OF ACADEMIC INTEGRITY
  • 2015-12 RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL in NATURE COMMUNICATIONS
  • 2015 Scientific Misconduct: Falsification, Fabrication, and Misappropriation of Credit in HANDBOOK OF ACADEMIC INTEGRITY
  • 2014-10 RIPK1- and RIPK3-induced cell death mode is determined by target availability in CELL DEATH & DIFFERENTIATION
  • 2014-02 Necroptosis induced by RIPK3 requires MLKL but not Drp1 in CELL DEATH & DISEASE
  • 2014 Cell Death and Cancer in CELL DEATH
  • 2014 Historical Perspective: The Seven Ages of Cell Death Research in CELL DEATH
  • 2014 IAPs and Necroptotic Cell Death in NECROTIC CELL DEATH
  • 2013-08 Another twist in the on and off affair between cell suicide and inflammation in CELL DEATH & DIFFERENTIATION
  • 2013-01 TNF can activate RIPK3 and cause programmed necrosis in the absence of RIPK1 in CELL DEATH & DISEASE
  • 2012-12-12 Research methods: Know when your numbers are significant in NATURE
  • 2012-05 In mouse embryonic fibroblasts, neither caspase-8 nor cellular FLICE-inhibitory protein (FLIP) is necessary for TNF to activate NF-κB, but caspase-8 is required for TNF to cause cell death, and induction of FLIP by NF-κB is required to prevent it in CELL DEATH & DIFFERENTIATION
  • 2010-03 RIPK1 is not essential for TNFR1-induced activation of NF-κB in CELL DEATH & DIFFERENTIATION
  • 2009-04 Puma indirectly activates Bax to cause apoptosis in the absence of Bid or Bim in CELL DEATH & DIFFERENTIATION
  • 2008-09 A tumour suppressor function of caspase-8? in CELL DEATH & DIFFERENTIATION
  • 2008-05 Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans in CELL DEATH & DIFFERENTIATION
  • 2008-05 ABT-737, proving to be a great tool even before it is proven in the clinic in CELL DEATH & DIFFERENTIATION
  • 2008-01 Cytoplasmic p53 is not required for PUMA-induced apoptosis in CELL DEATH & DIFFERENTIATION
  • 2007-02 Identification of mammalian mitochondrial proteins that interact with IAPs via N-terminal IAP binding motifs in CELL DEATH & DIFFERENTIATION
  • 2007-01 Caspase inhibitors: viral, cellular and chemical in CELL DEATH & DIFFERENTIATION
  • 2005-11 Classification of cell death: recommendations of the Nomenclature Committee on Cell Death in CELL DEATH & DIFFERENTIATION
  • 2005-09 IAPs – the ubiquitin connection in CELL DEATH & DIFFERENTIATION
  • 2005-04 IAPs, RINGs and ubiquitylation in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2005-01 XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland in CELL DEATH & DIFFERENTIATION
  • 2004-07 Early work on the function of Bcl-2, an interview with David Vaux in CELL DEATH & DIFFERENTIATION
  • 2004-04 Error message in NATURE
  • 2003-10 Alterations in the apoptotic machinery and their potential role in anticancer drug resistance in ONCOGENE
  • 2002-10 Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome in NATURE
  • 2002-08 Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9 in CELL DEATH & DIFFERENTIATION
  • 2002-07 Tissue distribution of Diablo/Smac revealed by monoclonal antibodies in CELL DEATH & DIFFERENTIATION
  • 2002-04 Cell death regulation by the mammalian IAP antagonist Diablo/Smac in APOPTOSIS
  • 2002-04 Apoptosis Timeline in CELL DEATH & DIFFERENTIATION
  • 2001-07 Inhibitor of apoptosis proteins and their relatives: IAPs and other BIRPs in GENOME BIOLOGY
  • 2000-12 Sequence as well as functional similarity for DIABLO/Smac and Grim, Reaper and Hid? in CELL DEATH & DIFFERENTIATION
  • 1999-11 Solution structure and mutagenesis of the caspase recruitment domain (CARD) from Apaf-1 in CELL DEATH & DIFFERENTIATION
  • 1999-11 Caspase inhibitors in CELL DEATH & DIFFERENTIATION
  • 1999-07-01 Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 1999-06 Caspases and apoptosis – biology and terminology in CELL DEATH & DIFFERENTIATION
  • 1999-04 Genes Inhibiting Caspases Rescue Neuronal Cells from Apoptosis and Allow Functional Survival of Cells Exposed to a Death Stimulus in PEDIATRIC RESEARCH
  • 1999-02 Signalling by CD95 and TNF receptors: Not only life and death in IMMUNOLOGY AND CELL BIOLOGY
  • 1999 Molecular Mechanisms of Apoptosis: An Overview in APOPTOSIS: BIOLOGY AND MECHANISMS
  • 1998-09 Immunopathology of apoptosis —introduction and overview in SEMINARS IN IMMUNOPATHOLOGY
  • 1998-07 Anti-apoptotic potential of insect cellular and viral IAPs in mammalian cells in CELL DEATH & DIFFERENTIATION
  • 1998-07 Retraction: Immunology: Ways around rejection in NATURE
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