Matthew H Porteus

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Matthew H



Publications in SciGraph latest 50 shown

  • 2019-01-28 Identification of preexisting adaptive immunity to Cas9 proteins in humans in NATURE MEDICINE
  • 2018-12 Efficient scarless genome editing in human pluripotent stem cells in NATURE METHODS
  • 2018-08 A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells in NATURE MEDICINE
  • 2018-01-25 CRISPR/Cas9 genome editing in human hematopoietic stem cells in NATURE PROTOCOLS
  • 2017 Genome Editing for the β-Hemoglobinopathies in GENE AND CELL THERAPIES FOR BETA-GLOBINOPATHIES
  • 2016-11 CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells in NATURE
  • 2016-02-18 Mutations in the nuclear bile acid receptor FXR cause progressive familial intrahepatic cholestasis in NATURE COMMUNICATIONS
  • 2015-12 Editing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin in NATURE COMMUNICATIONS
  • 2015-12 Towards a new era in medicine: therapeutic genome editing in GENOME BIOLOGY
  • 2015-09 Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells in NATURE BIOTECHNOLOGY
  • 2015-03 Genome Editing of the Blood: Opportunities and Challenges in CURRENT STEM CELL REPORTS
  • 2015 Strategies to Increase Genome Editing Frequencies and to Facilitate the Identification of Edited Cells in CHROMOSOMAL MUTAGENESIS
  • 2014-12 Phosphorylation of EXO1 by CDKs 1 and 2 regulates DNA end resection and repair pathway choice in NATURE COMMUNICATIONS
  • 2014-05 Lentiviral and targeted cellular barcoding reveals ongoing clonal dynamics of cell lines in vitro and in vivo in GENOME BIOLOGY
  • 2013-12 A survey of ex vivo/in vitro transduction efficiency of mammalian primary cells and cell lines with Nine natural adeno-associated virus (AAV1-9) and one engineered adeno-associated virus serotype in VIROLOGY JOURNAL
  • 2013 Nuclease Mediated Targeted Genome Modification in Mammalian Cells in SITE-DIRECTED INSERTION OF TRANSGENES
  • 2013-01 Zinc-finger nuclease-mediated gene correction using single AAV vector transduction and enhancement by Food and Drug Administration-approved drugs in GENE THERAPY
  • 2012-01 Gene editing: not just for translation anymore in NATURE METHODS
  • 2011-10 Zinc fingers hit off target in NATURE MEDICINE
  • 2011-08 Seeing the light: integrating genome engineering with double-strand break repair in NATURE METHODS
  • 2010-09 Self-complementary AAV mediates gene targeting and enhances endonuclease delivery for double-strand break repair in GENE THERAPY
  • 2009-05 Plant biotechnology: Zinc fingers on target in NATURE
  • 2008 Design and Testing of Zinc Finger Nucleases for Use in Mammalian Cells in CHROMOSOMAL MUTAGENESIS
  • 2006-08 Standardized reagents and protocols for engineering zinc finger nucleases by modular assembly in NATURE PROTOCOLS
  • 2005-08 Gene targeting using zinc finger nucleases in NATURE BIOTECHNOLOGY
  • 2005-06 Highly efficient endogenous human gene correction using designed zinc-finger nucleases in NATURE
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