Grant A Mcarthur


Ontology type: schema:Person     


Person Info

NAME

Grant A

SURNAME

Mcarthur

Publications in SciGraph latest 50 shown

  • 2019-12 Changes in long-range rDNA-genomic interactions associate with altered RNA polymerase II gene programs during malignant transformation in COMMUNICATIONS BIOLOGY
  • 2018-12 Multiplex immunohistochemistry accurately defines the immune context of metastatic melanoma in SCIENTIFIC REPORTS
  • 2018-09 A phase I study of panobinostat in pediatric patients with refractory solid tumors, including CNS tumors in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2018-05 Tumour mutation status and melanoma recurrence following a negative sentinel lymph node biopsy in BRITISH JOURNAL OF CANCER
  • 2018-03-20 Health-related quality of life impact of cobimetinib in combination with vemurafenib in patients with advanced or metastatic BRAFV600 mutation–positive melanoma in BRITISH JOURNAL OF CANCER
  • 2017-12 Checkpoint inhibitors in melanoma and early phase development in solid tumors: what’s the future? in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2017-12 Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer in NATURE COMMUNICATIONS
  • 2017-12 Clinical features of serous retinopathy observed with cobimetinib in patients with BRAF-mutated melanoma treated in the randomized coBRIM study in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2017-09-26 Tumour mutation status and sites of metastasis in patients with cutaneous melanoma in BRITISH JOURNAL OF CANCER
  • 2017-08 The Advantages and Challenges of Using FDG PET/CT for Response Assessment in Melanoma in the Era of Targeted Agents and Immunotherapy in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2017-06-06 Efficacy of anti-PD-1 therapy in patients with melanoma brain metastases in BRITISH JOURNAL OF CANCER
  • 2017-04 Reply to ‘Comment on ‘Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy’’ in BRITISH JOURNAL OF CANCER
  • 2017 Management of Melanoma in PET/CT IN MELANOMA
  • 2017 Melanoma in PET/CT IN MELANOMA
  • 2017 Pathology of Melanoma in PET/CT IN MELANOMA
  • 2016-10 A community-based model of rapid autopsy in end-stage cancer patients in NATURE BIOTECHNOLOGY
  • 2016-07 Melanoma and immunotherapy bridge 2015 in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2016-06 Cell Cycle Regulation and Melanoma in CURRENT ONCOLOGY REPORTS
  • 2016-05 Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy in BRITISH JOURNAL OF CANCER
  • 2016-02 Sentinel Lymph Node Biopsy in T4 Melanoma: An Important Risk-Stratification Tool in ANNALS OF SURGICAL ONCOLOGY
  • 2015-12 Updated efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in metastatic melanoma patients previously treated with anti-PD-1 therapy in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2015-12 coBRIM: a phase 3, double-blind, placebo-controlled study of vemurafenib versus vemurafenib + cobimetinib in previously untreated BRAFV600 mutation–positive patients with unresectable locally advanced or metastatic melanoma (NCT01689519) in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2015-12 Novel combination therapies for BRAF-mutant melanoma in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2015-04-23 Melanoma in NATURE REVIEWS DISEASE PRIMERS
  • 2015-04 Low-dose cyclophosphamide enhances antigen-specific CD4+ T cell responses to NY-ESO-1/ISCOMATRIX™ vaccine in patients with advanced melanoma in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2014-12 Sequence artefacts in a prospective series of formalin-fixed tumours tested for mutations in hotspot regions by massively parallel sequencing in BMC MEDICAL GENOMICS
  • 2014-11 The Epigenetic Regulator I-BET151 Induces BIM-Dependent Apoptosis and Cell Cycle Arrest of Human Melanoma Cells in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2014-05 Updated results and correlative FDG-PET analysis of a phase IB study of vemurafenib and cobimetinib (MEK inhibitor [GDC-0973]), in advanced BRAFV600- mutated melanoma (BRIM7) in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2014-05 Biomarker analysis of on-treatment and at progression biopsies from BRIM7 - a phase 1B trial of combined vemurafenib and cobimetinib treatment in BRAF V600 mutated melanoma in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2013-12 Future perspectives in melanoma research. Meeting report from the “Melanoma Bridge. Napoli, December 2nd-4th 2012” in JOURNAL OF TRANSLATIONAL MEDICINE
  • 2013-12 Targeted-capture massively-parallel sequencing enables robust detection of clinically informative mutations from formalin-fixed tumours in SCIENTIFIC REPORTS
  • 2013-12 A multisite blinded study for the detection of BRAF mutations in formalin-fixed, paraffin-embedded malignant melanoma in SCIENTIFIC REPORTS
  • 2013-06 ATRA and the specific RARα agonist, NRX195183, have opposing effects on the clonogenicity of pre-leukemic murine AML1-ETO bone marrow cells in LEUKEMIA
  • 2013-05 Dysregulation of the basal RNA polymerase transcription apparatus in cancer in NATURE REVIEWS CANCER
  • 2013-02 A phase I trial of imatinib in combination with mFOLFOX6–bevacizumab in patients with advanced colorectal cancer in CANCER CHEMOTHERAPY AND PHARMACOLOGY
  • 2012-12 Targeting oncogenes in advanced melanoma in HEREDITARY CANCER IN CLINICAL PRACTICE
  • 2012-03 Efficacy of CHK inhibitors as single agents in MYC-driven lymphoma cells in ONCOGENE
  • 2010-12 Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation in NATURE
  • 2010-09 Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma in NATURE
  • 2010-04 Clinical responses observed with imatinib or sorafenib in melanoma patients expressing mutations in KIT in BRITISH JOURNAL OF CANCER
  • 2009-12 Gene expression profiling identifies activated growth factor signaling in poor prognosis (Luminal-B) estrogen receptor positive breast cancer in BMC MEDICAL GENOMICS
  • 2009-04 O6-methylguanine-DNA methyltransferase depletion and DNA damage in patients with melanoma treated with temozolomide alone or with lomeguatrib in BRITISH JOURNAL OF CANCER
  • 2008-10 IL-21 induces in vivo immune activation of NK cells and CD8+ T cells in patients with metastatic melanoma and renal cell carcinoma in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2007-10 Dermatofibrosarcoma Protuberans: Recent Clinical Progress in ANNALS OF SURGICAL ONCOLOGY
  • 2007-10 Safety and efficacy of combining ATRA with G-CSF in HSPC mobilization; a pilot study in multiple myeloma and non-Hodgkin's lymphoma patients in BONE MARROW TRANSPLANTATION
  • 2007-09 Incorporation of somatic BRAF mutation testing into an algorithm for the investigation of hereditary non-polyposis colorectal cancer in FAMILIAL CANCER
  • 2007-04 Distinct Clinical and Pathological Features Are Associated with the BRAFT1799A(V600E) Mutation in Primary Melanoma in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2006-04 Multi-tracer small animal PET imaging of the tumour response to the novel pan-Erb-B inhibitor CI-1033 in EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
  • 2005-02 Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells in NATURE CELL BIOLOGY
  • 2004-08 Brca1 inactivation induces p27Kip1-dependent cell cycle arrest and delayed development in the mouse mammary gland in ONCOGENE
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