André Nussenzweig

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Publications in SciGraph latest 50 shown

  • 2018-12 Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis in NATURE COMMUNICATIONS
  • 2018-04 Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage in NATURE CELL BIOLOGY
  • 2018-03 Atm reactivation reverses ataxia telangiectasia phenotypes in vivo in CELL DEATH & DISEASE
  • 2017-12 Replication fork reversal triggers fork degradation in BRCA2-defective cells in NATURE COMMUNICATIONS
  • 2017-07-05 The multifaceted roles of PARP1 in DNA repair and chromatin remodelling in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2016-08-08 Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies in NATURE COMMUNICATIONS
  • 2016-08 More end resection is not merrier in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2016-07 Replication fork stability confers chemoresistance in BRCA-deficient cells in NATURE
  • 2016-05 The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study in BRITISH JOURNAL OF CANCER
  • 2015-10 The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development in NATURE MEDICINE
  • 2014-12 Replication initiation and genome instability: a crossroads for DNA and RNA synthesis in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2014-10 DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier in NATURE
  • 2013-07 End-joining, translocations and cancer in NATURE REVIEWS CANCER
  • 2012-02-07 DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes in NATURE
  • 2009-08 A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging in NATURE GENETICS
  • 2009-07 Mechanisms promoting translocations in editing and switching peripheral B cells in NATURE
  • 2009-06 The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks in NATURE
  • 2009-05 Histone H2AX is integral to hypoxia-driven neovascularization in NATURE MEDICINE
  • 2009-01-16 Monitoring DNA Breaks in Optically Highlighted Chromatin in Living Cells by Laser Scanning Confocal Microscopy in CHROMATIN PROTOCOLS
  • 2009-01 Activation of ATM depends on chromatin interactions occurring before induction of DNA damage in NATURE CELL BIOLOGY
  • 2008-11 53BP1 facilitates long-range DNA end-joining during V(D)J recombination in NATURE
  • 2007-12 Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly in ONCOGENE
  • 2007-08 Antigen receptor diversification and chromosome translocations in NATURE IMMUNOLOGY
  • 2007-07 Chromatin dynamics and the preservation of genetic information in NATURE
  • 2007-06-07 The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks in NATURE
  • 2007-06-07 Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age in NATURE
  • 2007-06 Positional stability of single double-strand breaks in mammalian cells in NATURE CELL BIOLOGY
  • 2006-09 Autophosphorylation at serine 1987 is dispensable for murine Atm activation in vivo in NATURE
  • 2006-03 Role of genomic instability and p53 in AID-induced c-myc–Igh translocations in NATURE
  • 2006-01 DNA repair: Tails of histones lost in NATURE
  • 2005-07 Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models in NATURE CELL BIOLOGY
  • 2005-01 Silencing of unsynapsed meiotic chromosomes in the mouse in NATURE GENETICS
  • 2004-07 Aging counts on chromosomes in NATURE GENETICS
  • 2003-07 Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks in NATURE CELL BIOLOGY
  • 2002-12 DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1 in NATURE CELL BIOLOGY
  • 2001-12 AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching in NATURE
  • 2000-03 DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation in NATURE
  • 1999-01 Secondary V(D)J recombination in B-1 cells in NATURE
  • 1996-08 Requirement for Ku80 in growth and immunoglobulin V(D)J recombination in NATURE
  • 1996 Thermotolerance and heat shock proteins: Possible involvement of Ku autoantigen in regulating Hsp70 expression in STRESS-INDUCIBLE CELLULAR RESPONSES
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