Brian J Sutton

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Brian J



Publications in SciGraph latest 50 shown

  • 2018-12 Structural basis for selective inhibition of immunoglobulin E-receptor interactions by an anti-IgE antibody in SCIENTIFIC REPORTS
  • 2017-12 IgE binds asymmetrically to its B cell receptor CD23 in SCIENTIFIC REPORTS
  • 2017-12 IgE Trimers Drive SPE-7 Cytokinergic Activity in SCIENTIFIC REPORTS
  • 2016-01 IgG4 Characteristics and Functions in Cancer Immunity in CURRENT ALLERGY AND ASTHMA REPORTS
  • 2015-08 Mechanism of the Antigen-Independent Cytokinergic SPE-7 IgE Activation of Human Mast Cells in Vitro in SCIENTIFIC REPORTS
  • 2014-04 Human immunoglobulin E flexes between acutely bent and extended conformations in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2013-12 Immunology: Allergy's Achilles' heel? in NATURE CHEMICAL BIOLOGY
  • 2013-12 The propeptide of human thyroid peroxidase is not required for its cellular, enzymatic or immunological activity in THYROID RESEARCH
  • 2011-05 Conformational changes in IgE contribute to its uniquely slow dissociation rate from receptor FcɛRI in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2008-03 IgE in allergy and asthma today in NATURE REVIEWS IMMUNOLOGY
  • 2008-02 Role of IgE receptors in IgE antibody-dependent cytotoxicity and phagocytosis of ovarian tumor cells by human monocytic cells in CANCER IMMUNOLOGY, IMMUNOTHERAPY
  • 2007-04 The first avian Ig-like Fc receptor family member combines features of mammalian FcR and FCRL in IMMUNOGENETICS
  • 2002-07 The crystal structure of IgE Fc reveals an asymmetrically bent conformation in NATURE IMMUNOLOGY
  • 2001-05-01 The structure of the IgE Cɛ2 domain and its role in stabilizing the complex with its high-affinity receptor FcɛRIα in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2000-11 Molecular model of a lattice of signalling proteins involved in bacterial chemotaxis in NATURE CELL BIOLOGY
  • 1998 The Structure of a Human Rheumatoid Factor Bound to IgG Fc in GLYCOIMMUNOLOGY 2
  • 1997-05 Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody—antigen interaction in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 1997-05 Basis of the 1:1 stoichiometry of the high affinity receptor FcεRI-IgE complex in EUROPEAN BIOPHYSICS JOURNAL
  • 1996-05 Structure based design and characterization of peptides that inhibit IgE binding to its high-affinity receptor in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 1994 Idiotypes of DNA-Binding Autoantibodies:Mapping by Epitope Scanning and Molecular Modelling in AUTOIMMUNITY: EXPERIMENTAL ASPECTS
  • 1993-12 The human IgE network in NATURE
  • 1993-11-28 Crystallization of Membrane Proteins for X-Ray Analysis in BIOMEMBRANE PROTOCOLS
  • 1986-03 Tertiary structural similarity between a class A β-lactamase and a penicillin-sensitive D-alanyl carboxypeptidase-transpeptidase in NATURE
  • 1985-08 Association of rheumatoid arthritis and primary osteoarthritis with changes in the glycosylation pattern of total serum IgG in NATURE
  • 1977-03 Structure of an antibody combining site by magnetic resonance in NATURE
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