Paul A Northcott

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Paul A



Publications in SciGraph latest 50 shown

  • 2019-12 Lsd1 as a therapeutic target in Gfi1-activated medulloblastoma in NATURE COMMUNICATIONS
  • 2018-12 Proteomic analysis of Medulloblastoma reveals functional biology with translational potential in ACTA NEUROPATHOLOGICA COMMUNICATIONS
  • 2018-12 Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors in NATURE COMMUNICATIONS
  • 2018-11 A biobank of patient-derived pediatric brain tumor models in NATURE MEDICINE
  • 2018-07 Author Correction: The landscape of genomic alterations across childhood cancers in NATURE
  • 2018-06 UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs in NATURE GENETICS
  • 2018-04 Deep sequencing of WNT-activated medulloblastomas reveals secondary SHH pathway activation in ACTA NEUROPATHOLOGICA
  • 2018-03 DNA methylation-based classification of central nervous system tumours in NATURE
  • 2018-01 Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling in NATURE
  • 2017-12 DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma in ACTA NEUROPATHOLOGICA
  • 2017-09-14 Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells in ONCOGENE
  • 2017-07 The whole-genome landscape of medulloblastoma subtypes in NATURE
  • 2017-07 Cancer: Keeping it real to kill glioblastoma in NATURE
  • 2017-05 Spatial heterogeneity in medulloblastoma in NATURE GENETICS
  • 2017-03-20 Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme in NATURE COMMUNICATIONS
  • 2017-01 Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking in NATURE GENETICS
  • 2016-06 Risk stratification of childhood medulloblastoma in the molecular era: the current consensus in ACTA NEUROPATHOLOGICA
  • 2016-02 Active medulloblastoma enhancers reveal subgroup-specific cellular origins in NATURE
  • 2016-02 Gliomatosis cerebri in children shares molecular characteristics with other pediatric gliomas in ACTA NEUROPATHOLOGICA
  • 2016-01 Divergent clonal selection dominates medulloblastoma at recurrence in NATURE
  • 2015-12 Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling in NATURE COMMUNICATIONS
  • 2015-05 Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers in ACTA NEUROPATHOLOGICA
  • 2015-05 Aberrant immunostaining pattern of the CD24 glycoprotein in clinical samples and experimental models of pediatric medulloblastomas in JOURNAL OF NEURO-ONCOLOGY
  • 2015-02 The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variants in ONCOGENE
  • 2015 Medulloblastoma and CNS Primitive Neuroectodermal Tumors in MOLECULAR PATHOLOGY OF NERVOUS SYSTEM TUMORS
  • 2014-08 Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity in ACTA NEUROPATHOLOGICA
  • 2014-07 Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma in NATURE
  • 2014-07 Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort in ACTA NEUROPATHOLOGICA
  • 2014-07 Genomic and transcriptomic analyses match medulloblastoma mouse models to their human counterparts in ACTA NEUROPATHOLOGICA
  • 2014-06 Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing in NATURE
  • 2014-02 Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group in ACTA NEUROPATHOLOGICA
  • 2013-12 TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma in ACTA NEUROPATHOLOGICA
  • 2013-12 Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system in ACTA NEUROPATHOLOGICA
  • 2013-08 Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma in NATURE GENETICS
  • 2013-08 Signatures of mutational processes in human cancer in NATURE
  • 2013-06 Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays in ACTA NEUROPATHOLOGICA
  • 2013-03 DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies in ACTA NEUROPATHOLOGICA
  • 2013-03 Aberrant patterns of H3K4 and H3K27 histone lysine methylation occur across subgroups in medulloblastoma in ACTA NEUROPATHOLOGICA
  • 2012-12 Medulloblastomics: the end of the beginning in NATURE REVIEWS CANCER
  • 2012-12 LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR) in ACTA NEUROPATHOLOGICA
  • 2012-10 ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing in BMC PROCEEDINGS
  • 2012-08 Dissecting the genomic complexity underlying medulloblastoma in NATURE
  • 2012-08 Subgroup-specific structural variation across 1,000 medulloblastoma genomes in NATURE
  • 2012-08 Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations in NATURE
  • 2012-06 The clinical implications of medulloblastoma subgroups in NATURE REVIEWS NEUROLOGY
  • 2012-04 Molecular subgroups of medulloblastoma: the current consensus in ACTA NEUROPATHOLOGICA
  • 2012-04 Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation in ONCOGENE
  • 2012-04 Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas in ACTA NEUROPATHOLOGICA
  • 2012-04 Subgroup-specific alternative splicing in medulloblastoma in ACTA NEUROPATHOLOGICA
  • 2012-04 Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples in ACTA NEUROPATHOLOGICA
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