Joan S Brugge

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Joan S



Publications in SciGraph latest 50 shown

  • 2017-12 Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo in NPJ BREAST CANCER
  • 2017-12 Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response in NATURE COMMUNICATIONS
  • 2017-12 Erratum: Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo in NPJ BREAST CANCER
  • 2017-05 Metabolic changes promote rejection of oncogenic cells in NATURE CELL BIOLOGY
  • 2017-01-10 Starved epithelial cells uptake extracellular matrix for survival in NATURE COMMUNICATIONS
  • 2016-07 Coping with the metabolic stress of leaving home in CELL RESEARCH
  • 2016-07 A protein interaction map for cell-cell adhesion regulators identifies DUSP23 as a novel phosphatase for β-catenin in SCIENTIFIC REPORTS
  • 2015-12 Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours in NATURE COMMUNICATIONS
  • 2015-11 Cancer: The enemy of my enemy is my friend in NATURE
  • 2014-06 Oncogene-like induction of cellular invasion from centrosome amplification in NATURE
  • 2013-08 Evidence for a multipotent mammary progenitor with pregnancy-specific activity in BREAST CANCER RESEARCH
  • 2012-06 Altered metabolic requirements in cancer cell migration and metastasis in BMC PROCEEDINGS
  • 2012-06 Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis in BMC PROCEEDINGS
  • 2012-04 Into the deep: Refocusing on 3D in NATURE CELL BIOLOGY
  • 2012-02 Outgrowth of single oncogene-expressing cells from suppressive epithelial environments in NATURE
  • 2011-09 Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis in NATURE GENETICS
  • 2011-04 The myosin-II-responsive focal adhesion proteome: a tour de force? in NATURE CELL BIOLOGY
  • 2011-03-20 The myosin-II-responsive focal adhesion proteome: a tour de force? in NATURE CELL BIOLOGY
  • 2011-03 A non-genetic route to aneuploidy in human cancers in NATURE CELL BIOLOGY
  • 2010-04 Identifying single-cell molecular programs by stochastic profiling in NATURE METHODS
  • 2009-12 YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway in NATURE CELL BIOLOGY
  • 2009-11 Transcriptional regulation of metastatic [Id]entity by KLF17 in GENOME BIOLOGY
  • 2009-11 Activity of the multikinase inhibitor dasatinib against ovarian cancer cells in BRITISH JOURNAL OF CANCER
  • 2009-09 Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment in NATURE
  • 2008-10 The cell biology of cell-in-cell structures in NATURE REVIEWS MOLECULAR CELL BIOLOGY
  • 2008-09 Identification of genes that regulate epithelial cell migration using an siRNA screening approach in NATURE CELL BIOLOGY
  • 2007-10 Engineering tumors with 3D scaffolds in NATURE METHODS
  • 2007-08 Common effector processing mediates cell-specific responses to stimuli in NATURE
  • 2006-12 An active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligand in CELL COMMUNICATION AND SIGNALING
  • 2006-11 SePARating polarity and proliferation in ErbB2 oncogenesis in NATURE CELL BIOLOGY
  • 2006-06 p63 regulates an adhesion programme and cell survival in epithelial cells in NATURE CELL BIOLOGY
  • 2005-09 Activation of NF-κB following detachment delays apoptosis in intestinal epithelial cells in ONCOGENE
  • 2005-09 Modelling glandular epithelial cancers in three-dimensional cultures in NATURE REVIEWS CANCER
  • 2004-10 Use of Three-Dimensional Basement Membrane Cultures to Model Oncogene-Induced Changes in Mammary Epithelial Morphogenesis in JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA
  • 2004-06 A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth in ONCOGENE
  • 2003-08 Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis in NATURE CELL BIOLOGY
  • 2002-04 Sensing the environment: a historical perspective on integrin signal transduction in NATURE CELL BIOLOGY
  • 2001-09 ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini in NATURE CELL BIOLOGY
  • 1998-08 Casting light on focal adhesions in NATURE GENETICS
  • 1995-06 Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation in NATURE
  • 1992-12 Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases in NATURE
  • 1988 Expression of the C-SRC Proto-Oncogene Product in Neural Cells in NEURAL DEVELOPMENT AND REGENERATION
  • 1987 Comparison of the Structural and Functional Properties of the Viral and Cellular src Gene Products in DEVELOPMENT AND RECOGNITION OF THE TRANSFORMED CELL
  • 1986 Interaction of the Rous Sarcoma Virus Protein pp60 src with the Cellular Proteins pp50 and pp90 in RETROVIRUSES 4
  • 1985-08 Neurones express high levels of a structurally modified, activated form of pp60c-src in NATURE
  • 1982-01 Rous sarcoma virus-induced phosphorylation of a 50,000-molecular weight cellular protein in NATURE
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