Taha Merghoub


Ontology type: schema:Person     


Person Info

NAME

Taha

SURNAME

Merghoub

Publications in SciGraph latest 50 shown

  • 2017-11 A neoantigen fitness model predicts tumour response to checkpoint blockade immunotherapy in NATURE
  • 2017-05 Chromatin states define tumour-specific T cell dysfunction and reprogramming in NATURE
  • 2017-02-13 Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity in NATURE COMMUNICATIONS
  • 2016-11 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2016-11 Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells in NATURE
  • 2016-03 IL-6/NOS2 inflammatory signals regulate MMP-9 and MMP-2 activity and disease outcome in nasopharyngeal carcinoma patients in TUMOR BIOLOGY
  • 2015-12 Direct comparisons of T cell costimulation and checkpoint blockade in the setting of tumor-targeted monoclonal antibody therapy in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2014-12 Potentiation of immunomodulatory antibodies with oncolytic viruses for therapy of poorly-immunogenic tumors in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2014-12 Impairment of Treg suppression by GITR ligation is effective selectively in the context of a pro-inflammatory tumor microenvironment in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2014-12 Blockade of surface bound TGF-β abrogates Treg suppression of effector T cell function within the tumor microenvironment in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2014-12 Expression of indoleamine 2.3-dioxygenase by tumors induces local and systemic immunosuppressive effects in a murine melanoma model in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2013-11 Localized oncolytic virotherapy inflames distant tumors and synergizes with immune checkpoint blockade leading to systemic tumor rejection in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2013-11 Blockade of Treg derived TGF-β abrogates suppression of effector T cell function within the tumor microenvironment in JOURNAL FOR IMMUNOTHERAPY OF CANCER
  • 2012-01 Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring V600EBRAF in ONCOGENE
  • 2005-01 Role of the proto-oncogene Pokemon in cellular transformation and ARF repression in NATURE
  • 2000-09 BCL-6 regulates chemokine gene transcription in macrophages in NATURE IMMUNOLOGY
  • 1999-09 In vivo analysis of the molecular pathogenesis of acute promyelocytic leukemia in the mouse and its therapeutic implications in ONCOGENE
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