Osamu Nureki

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Publications in SciGraph latest 50 shown

  • 2022-06-29 Structure of the Dicer-2–R2D2 heterodimer bound to a small RNA duplex in NATURE
  • 2022-05-26 Automated amplification-free digital RNA detection platform for rapid and sensitive SARS-CoV-2 diagnosis in COMMUNICATIONS BIOLOGY
  • 2022-05-06 Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1 in NATURE COMMUNICATIONS
  • 2022-03-08 Engineered Campylobacter jejuni Cas9 variant with enhanced activity and broader targeting range in COMMUNICATIONS BIOLOGY
  • 2021-11-15 Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2 in NATURE COMMUNICATIONS
  • 2021-09-22 Structural basis of gating modulation of Kv4 channel complexes in NATURE
  • 2021-08-05 Cryo-EM structure of the human MT1–Gi signaling complex in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2021-06-23 Precise CAG repeat contraction in a Huntington’s Disease mouse model is enabled by gene editing with SpCas9-NG in COMMUNICATIONS BIOLOGY
  • 2021-04-19 Amplification-free RNA detection with CRISPR–Cas13 in COMMUNICATIONS BIOLOGY
  • 2021-01-06 Mitochondrial sorting and assembly machinery operates by β-barrel switching in NATURE
  • 2020-11-09 Isoprenoid-chained lipid EROCOC17+4: a new matrix for membrane protein crystallization and a crystal delivery medium in serial femtosecond crystallography in SCIENTIFIC REPORTS
  • 2020-11-05 Structural insights into the mechanism of rhodopsin phosphodiesterase in NATURE COMMUNICATIONS
  • 2020-09-16 Taste transduction and channel synapses in taste buds in PFLÜGERS ARCHIV - EUROPEAN JOURNAL OF PHYSIOLOGY
  • 2020-09-11 Kidney GATA3+ regulatory T cells play roles in the convalescence stage after antibody-mediated renal injury in CELLULAR & MOLECULAR IMMUNOLOGY
  • 2020-06-22 The structure of lipid nanodisc-reconstituted TRPV3 reveals the gating mechanism in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2020-06-05 Publisher Correction: Base editors for simultaneous introduction of C-to-T and A-to-G mutations in NATURE BIOTECHNOLOGY
  • 2020-06-02 Base editors for simultaneous introduction of C-to-T and A-to-G mutations in NATURE BIOTECHNOLOGY
  • 2020-05-15 Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation in COMMUNICATIONS BIOLOGY
  • 2020-03-30 Structural insights into tetraspanin CD9 function in NATURE COMMUNICATIONS
  • 2020-03-09 Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2020-02-12 Crystal structure of Drosophila Piwi in NATURE COMMUNICATIONS
  • 2020-01-30 Author Correction: Structural basis for the drug extrusion mechanism by a MATE multidrug transporter in NATURE
  • 2019-09-25 Crystal structure of heliorhodopsin in NATURE
  • 2019-06-21 Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500 in COMMUNICATIONS BIOLOGY
  • 2019-06-03 Cryo-EM structure of the human L-type amino acid transporter 1 in complex with glycoprotein CD98hc in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2019-04-29 Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9 in NATURE COMMUNICATIONS
  • 2019-02-11 Crystal structure of plant vacuolar iron transporter VIT1 in NATURE PLANTS
  • 2018-12-10 Genome editing in plants by engineered CRISPR–Cas9 recognizing NG PAM in NATURE PLANTS
  • 2018-11-09 Crystal structures of human ETB receptor provide mechanistic insight into receptor activation and partial activation in NATURE COMMUNICATIONS
  • 2018-10-24 Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1 in NATURE COMMUNICATIONS
  • 2018-10-12 DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells in NATURE COMMUNICATIONS
  • 2018-09-26 Crystal structure of the red light-activated channelrhodopsin Chrimson in NATURE COMMUNICATIONS
  • 2018-08-20 Cryo-EM structures of the human volume-regulated anion channel LRRC8 in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2017-11-25 Crystallographic Analysis of MATE-Type Multidrug Exporter with Its Inhibitors in BACTERIAL MULTIDRUG EXPORTERS
  • 2017-11-21 Structural basis for xenobiotic extrusion by eukaryotic MATE transporter in NATURE COMMUNICATIONS
  • 2017-11-17 Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate in NATURE COMMUNICATIONS
  • 2017-11-10 Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy in NATURE COMMUNICATIONS
  • 2017-10-12 Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel in NATURE COMMUNICATIONS
  • 2017-10-02 Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity in NATURE PLANTS
  • 2017-08-09 Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6 in NATURE
  • 2017-07-27 ATP-dependent modulation of MgtE in Mg2+ homeostasis in NATURE COMMUNICATIONS
  • 2017-07-03 Serial femtosecond crystallography structure of cytochrome c oxidase at room temperature in SCIENTIFIC REPORTS
  • 2017-06-23 CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice in SCIENTIFIC REPORTS
  • 2017-06-05 Engineered Cpf1 variants with altered PAM specificities in NATURE BIOTECHNOLOGY
  • 2017-04-06 Hydroxyethyl cellulose matrix applied to serial crystallography in SCIENTIFIC REPORTS
  • 2017-03-31 Atomic resolution structure of serine protease proteinase K at ambient temperature in SCIENTIFIC REPORTS
  • 2017-03-23 Structural insights into the nucleotide base specificity of P2X receptors in SCIENTIFIC REPORTS
  • 2017-02-20 Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL in NATURE
  • 2016-12-02 Crystal structures of the TRIC trimeric intracellular cation channel orthologues in CELL RESEARCH
  • 2016-10-25 Structural Biology of Chronic Inflammation-Associated Signalling Pathways: Toward Structure-Guided Drug Development in CHRONIC INFLAMMATION
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