Osamu Nureki

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Publications in SciGraph latest 50 shown

  • 2018-12-10 Genome editing in plants by engineered CRISPR–Cas9 recognizing NG PAM in NATURE PLANTS
  • 2018-12 Crystal structure of the red light-activated channelrhodopsin Chrimson in NATURE COMMUNICATIONS
  • 2018-12 Crystal structures of human ETB receptor provide mechanistic insight into receptor activation and partial activation in NATURE COMMUNICATIONS
  • 2018-12 DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells in NATURE COMMUNICATIONS
  • 2018-12 Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1 in NATURE COMMUNICATIONS
  • 2018-09 Cryo-EM structures of the human volume-regulated anion channel LRRC8 in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2018 Crystallographic Analysis of MATE-Type Multidrug Exporter with Its Inhibitors in BACTERIAL MULTIDRUG EXPORTERS
  • 2017-12 Atomic resolution structure of serine protease proteinase K at ambient temperature in SCIENTIFIC REPORTS
  • 2017-12 Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel in NATURE COMMUNICATIONS
  • 2017-12 Serial femtosecond crystallography structure of cytochrome c oxidase at room temperature in SCIENTIFIC REPORTS
  • 2017-12 Structural basis for xenobiotic extrusion by eukaryotic MATE transporter in NATURE COMMUNICATIONS
  • 2017-12 Structural insights into the nucleotide base specificity of P2X receptors in SCIENTIFIC REPORTS
  • 2017-12 ATP-dependent modulation of MgtE in Mg2+ homeostasis in NATURE COMMUNICATIONS
  • 2017-12 Hydroxyethyl cellulose matrix applied to serial crystallography in SCIENTIFIC REPORTS
  • 2017-12 Real-space and real-time dynamics of CRISPR-Cas9 visualized by high-speed atomic force microscopy in NATURE COMMUNICATIONS
  • 2017-12 Capturing an initial intermediate during the P450nor enzymatic reaction using time-resolved XFEL crystallography and caged-substrate in NATURE COMMUNICATIONS
  • 2017-12 CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice in SCIENTIFIC REPORTS
  • 2017-10 Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity in NATURE PLANTS
  • 2017-09 X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2017-08 Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6 in NATURE
  • 2017-06-05 Engineered Cpf1 variants with altered PAM specificities in NATURE BIOTECHNOLOGY
  • 2017-03 Light-induced structural changes and the site of O=O bond formation in PSII caught by XFEL in NATURE
  • 2016-12 Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide in SCIENTIFIC REPORTS
  • 2016-12 Crystal structures of the TRIC trimeric intracellular cation channel orthologues in CELL RESEARCH
  • 2016-09 Activation mechanism of endothelin ETB receptor by endothelin-1 in NATURE
  • 2016-08-24 Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis in NATURE COMMUNICATIONS
  • 2016-08-08 Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide in NATURE COMMUNICATIONS
  • 2016-08 Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase in SCIENTIFIC REPORTS
  • 2016-07-15 Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization in NATURE COMMUNICATIONS
  • 2016-07 Oil-free hyaluronic acid matrix for serial femtosecond crystallography in SCIENTIFIC REPORTS
  • 2016-05-30 Structural basis for amino acid export by DMT superfamily transporter YddG in NATURE
  • 2016-05 Structural basis for specific inhibition of Autotaxin by a DNA aptamer in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2016 Structural Biology of Chronic Inflammation-Associated Signalling Pathways: Toward Structure-Guided Drug Development in CHRONIC INFLAMMATION
  • 2015-12 Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin in NATURE COMMUNICATIONS
  • 2015-12 Atomistic design of microbial opsin-based blue-shifted optogenetics tools in NATURE COMMUNICATIONS
  • 2015-12 Structural basis for the facilitative diffusion mechanism by SemiSWEET transporter in NATURE COMMUNICATIONS
  • 2015-12 Structural basis for dynamic mechanism of nitrate/nitrite antiport by NarK in NATURE COMMUNICATIONS
  • 2015-11 Integrated molecular analysis of adult T cell leukemia/lymphoma in NATURE GENETICS
  • 2015-05 Crystal structure of Escherichia coli YidC, a membrane protein chaperone and insertase in SCIENTIFIC REPORTS
  • 2015-05 Structural basis for Na+ transport mechanism by a light-driven Na+ pump in NATURE
  • 2015-01 Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex in NATURE
  • 2015 Structural Biology of Protein Post-transcriptional Modifications and Cellular Signaling in PROTEIN MODIFICATIONS IN PATHOGENIC DYSREGULATION OF SIGNALING
  • 2015 Structure-Functional Analysis of Channelrhodopsins in OPTOGENETICS
  • 2014-12 Structural basis for ion selectivity revealed by high-resolution crystal structure of Mg2+ channel MgtE in NATURE COMMUNICATIONS
  • 2014-09 Conformational variation of the translocon enhancing chaperone SecDF in JOURNAL OF STRUCTURAL AND FUNCTIONAL GENOMICS
  • 2014-05 Structural basis of Sec-independent membrane protein insertion by YidC in NATURE
  • 2014-02 Somatic RHOA mutation in angioimmunoblastic T cell lymphoma in NATURE GENETICS
  • 2013-04 Structural basis for the drug extrusion mechanism by a MATE multidrug transporter in NATURE
  • 2013-04 Backbone resonance assignments for the cytoplasmic region of the Mg2+ transporter MgtE in the Mg2+-unbound state in BIOMOLECULAR NMR ASSIGNMENTS
  • 2012-11 Structure and function of Zucchini endoribonuclease in piRNA biogenesis in NATURE
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