Thomas Mandrup Poulsen

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Mandrup Poulsen

Publications in SciGraph latest 50 shown

  • 2018-02 Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice in DIABETOLOGIA
  • 2017-12-29 Immunometabolism in 2017: Metabolism and the inflammasome in health and ageing in NATURE REVIEWS ENDOCRINOLOGY
  • 2017-08 A guiding map for inflammation in NATURE IMMUNOLOGY
  • 2014-12 Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist in JOURNAL OF NEUROINFLAMMATION
  • 2014-12 Inhibition of beta cell growth and function by bone morphogenetic proteins in DIABETOLOGIA
  • 2013-06 Fasting and meal-stimulated residual beta cell function is positively associated with serum concentrations of proinflammatory cytokines and negatively associated with anti-inflammatory and regulatory cytokines in patients with longer term type 1 diabetes in DIABETOLOGIA
  • 2012-09 Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children in DIABETOLOGIA
  • 2012-05-16 Perspective: Testing failures in NATURE
  • 2011-05 Histone Deacetylase (HDAC) Inhibition as a Novel Treatment for Diabetes Mellitus in MOLECULAR MEDICINE
  • 2011-05 The Oral Histone Deacetylase Inhibitor ITF2357 Reduces Cytokines and Protects Islet β Cells In Vivo and In Vitro in MOLECULAR MEDICINE
  • 2011-03 Corrigendum: IAPP boosts islet macrophage IL-1 in type 2 diabetes in NATURE IMMUNOLOGY
  • 2010-12 Serum Proteome Pool Changes in Type 2 Diabetic Patients Treated with Anakinra in CLINICAL PROTEOMICS
  • 2010-12 Lysine deacetylases are produced in pancreatic beta cells and are differentially regulated by proinflammatory cytokines in DIABETOLOGIA
  • 2010-10 IAPP boosts islet macrophage IL-1 in type 2 diabetes in NATURE IMMUNOLOGY
  • 2010-10 Multifactorial treatment increases endothelial progenitor cells in patients with type 2 diabetes in DIABETOLOGIA
  • 2010-03 Blockade of interleukin 1 in type 1 diabetes mellitus in NATURE REVIEWS ENDOCRINOLOGY
  • 2010-01 The global diabetes epidemic as a consequence of lifestyle-induced low-grade inflammation in DIABETOLOGIA
  • 2009-02 IL-1β-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells in DIABETOLOGIA
  • 2008-10 Suppressor of cytokine signalling-3 expression inhibits cytokine-mediated destruction of primary mouse and rat pancreatic islets and delays allograft rejection in DIABETOLOGIA
  • 2008-05 The use of interleukin-1-receptor antagonists in the treatment of diabetes mellitus in NATURE REVIEWS ENDOCRINOLOGY
  • 2008-04 The imidazoline RX871024 induces death of proliferating insulin-secreting cells by activation of c-jun N-terminal kinase in CELLULAR AND MOLECULAR LIFE SCIENCES
  • 2008-01 Proliferation of sorted human and rat beta cells in DIABETOLOGIA
  • 2007-04 Inhibition of histone deacetylases prevents cytokine-induced toxicity in beta cells in DIABETOLOGIA
  • 2006-08 IL-1β-induced pro-apoptotic signalling is facilitated by NCAM/FGF receptor signalling and inhibited by the C3d ligand in the INS-1E rat beta cell line in DIABETOLOGIA
  • 2006-06 Association of a microsatellite in FASL to type II diabetes and of the FAS-670G>A genotype to insulin resistance in GENES & IMMUNITY
  • 2006-05 Growth arrest- and DNA-damage-inducible 45β gene inhibits c-Jun N-terminal kinase and extracellular signal-regulated kinase and decreases IL-1β-induced apoptosis in insulin-producing INS-1E cells in DIABETOLOGIA
  • 2006-02 Plasma cytokine levels in young and elderly twins: genes versus environment and relation to in vivo insulin action in DIABETOLOGIA
  • 2005-12 Extracellular signal-regulated kinase is essential for interleukin-1-induced and nuclear factor κB-mediated gene expression in insulin-producing INS-1E cells in DIABETOLOGIA
  • 2005-12 Functional promoter haplotypes of the human FAS gene are associated with the phenotype of SLE characterized by thrombocytopenia in GENES & IMMUNITY
  • 2005-10 Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt in DIABETOLOGIA
  • 2005-08 An immune origin of type 2 diabetes? in DIABETOLOGIA
  • 2005-06 An immune origin of type 2 diabetes? in DIABETOLOGIA
  • 2005-02 Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes in DIABETOLOGIA
  • 2004-11 Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1β-mediated toxicity through inhibition of multiple nuclear factor-κB-regulated proapoptotic pathways in DIABETOLOGIA
  • 2004-08 40th EASD Annual Meeting of the European Association for the Study of Diabetes in DIABETOLOGIA
  • 2004-07 Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity in DIABETOLOGIA
  • 2003-08 Inflammatory mediators and islet β-cell failure: a link between type 1 and type 2 diabetes in JOURNAL OF MOLECULAR MEDICINE
  • 2002-11 IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis in DIABETOLOGIA
  • 2002-01 Complete mutation scan of the human Fas ligand gene: Linkage studies in Type I diabetes mellitus families in DIABETOLOGIA
  • 2001-12 A choice of death – the signal-transduction of immune-mediated beta-cell apoptosis in DIABETOLOGIA
  • 2000-12 Characterization of new polymorphisms in the 5′UTR of the human interleukin-1 receptor type 1 (IL1R1) gene: linkage to type 1 diabetes and correlation to IL-1RI plasma level in GENES & IMMUNITY
  • 2000-11 The intercellular adhesion molecule-1 K469E polymorphism in type 1 diabetes in IMMUNOGENETICS
  • 2000-10 TNFα and IFNγ potentiate IL-1β induced mitogen activated protein kinase activity in rat pancreatic islets of Langerhans in DIABETOLOGIA
  • 2000-06 Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with Type I diabetes mellitus in DIABETOLOGIA
  • 1997 On the Pathogenesis of Insulin-Dependent Diabetes Mellitus in Man: A Paradigm in Transition in CONTRIBUTIONS OF PHYSIOLOGY TO THE UNDERSTANDING OF DIABETES
  • 1996-09 The role of interleukin-1 in the pathogenesis of IDDM in DIABETOLOGIA
  • 1993-08 Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats in DIABETOLOGIA
  • 1993-05 What are the types and cellular sources of free radicals in the pathogenesis of Type 1 (insulin-dependent) diabetes mellitus? in DIABETOLOGIA
  • 1990-12 Assessment of precision, concordance, specificity, and sensitivity of islet cell antibody measurement in 41 assays in DIABETOLOGIA
  • 1990-01 Functional and morphological effects of interleukin-1β on the perfused rat pancreas in DIABETOLOGIA
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