Mariano Barbacid


Ontology type: schema:Person     


Person Info

NAME

Mariano

SURNAME

Barbacid

Publications in SciGraph latest 50 shown

  • 2021-05-12 RASless MEFs as a Tool to Study RAS-Dependent and RAS-Independent Functions in RAS ACTIVITY AND SIGNALING
  • 2019-12-10 Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27 in SCIENTIFIC REPORTS
  • 2018-12-17 RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling in NATURE MEDICINE
  • 2018-07-02 Effects of a Ketogenic Diet on [18F]FDG-PET Imaging in a Mouse Model of Lung Cancer in MOLECULAR IMAGING AND BIOLOGY
  • 2017-08-02 Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS in NATURE
  • 2017-08-02 A Braf kinase-inactive mutant induces lung adenocarcinoma in NATURE
  • 2016-10-24 In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma in ONCOGENE
  • 2016-02-08 Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma in NATURE MEDICINE
  • 2015-11-03 Modeling K-Ras-driven lung adenocarcinoma in mice: preclinical validation of therapeutic targets in JOURNAL OF MOLECULAR MEDICINE
  • 2014-08-21 Mouse Models of RAS-Induced Tumors and Developmental Disorders in RAS SUPERFAMILY SMALL G PROTEINS: BIOLOGY AND MECHANISMS 1
  • 2014-03-18 Reply: ‘Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer’ in BRITISH JOURNAL OF CANCER
  • 2013-10-25 Reversible, interrelated mRNA and miRNA expression patterns in the transcriptome of Rasless fibroblasts: functional and mechanistic implications in BMC GENOMICS
  • 2013-08-01 Stromal disrupting effects of nab-paclitaxel in pancreatic cancer in BRITISH JOURNAL OF CANCER
  • 2013-07-08 Ras signaling is essential for skin development in ONCOGENE
  • 2011-11-27 Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2010-11-13 Updating the Mammalian Cell Cycle: The Role of Interphase Cdks in Tissue Homeostasis and Cancer in TWO FACES OF EVIL: CANCER AND NEURODEGENERATION
  • 2010-10-18 Upregulation of miR-21 by Ras in vivo and its role in tumor growth in ONCOGENE
  • 2010-05-30 DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2009-12-13 Cdk2 suppresses cellular senescence induced by the c-myc oncogene in NATURE CELL BIOLOGY
  • 2009-03 Cell cycle, CDKs and cancer: a changing paradigm in NATURE REVIEWS CANCER
  • 2007-08-16 Cdk1 is sufficient to drive the mammalian cell cycle in NATURE
  • 2007-04-29 p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation in NATURE GENETICS
  • 2006-01-09 Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication in ONCOGENE
  • 2005-08 Senescence in premalignant tumours in NATURE
  • 2004-04-01 La necesidad de un Pacto de Estado por la Ciencia en España in CLINICAL AND TRANSLATIONAL ONCOLOGY
  • 2004-04-01 Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes in DIABETOLOGIA
  • 2003-09 Correction: RAS oncogenes: The first 30 years in NATURE REVIEWS CANCER
  • 2003-08-17 Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice in NATURE GENETICS
  • 2003-08-14 Genetic rescue of Cdk4 null mice restores pancreatic β-cell proliferation but not homeostatic cell number in ONCOGENE
  • 2003-06 RAS oncogenes: the first 30 years in NATURE REVIEWS CANCER
  • 2003 Driving the Cell Cycle to Cancer in NEW TRENDS IN CANCER FOR THE 21STCENTURY
  • 2001-12 To cycle or not to cycle: a critical decision in cancer in NATURE REVIEWS CANCER
  • 2001-06 Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling in NATURE IMMUNOLOGY
  • 1999-05 Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia in NATURE GENETICS
  • 1997-11-20 Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation in ONCOGENE
  • 1997-10 Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system in CELL AND TISSUE RESEARCH
  • 1997-07-03 A giant protein that stimulates guanine nucleotide exchange on ARF1 and Rab proteins forms a cytosolic ternary complex with clathrin and Hsp70 in ONCOGENE
  • 1997-05 ERRATUM in CLINICAL & EXPERIMENTAL METASTASIS
  • 1997 Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system in MOLECULAR BASES OF AXONAL GROWTH AND PATHFINDING
  • 1996-07 Renal agenesis and the absence of enteric neurons in mice lacking GDNF in NATURE
  • 1995-03 Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CDS+thymocytes in NATURE
  • 1994-03 Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements in NATURE
  • 1994-03 Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene in NATURE
  • 1992-03 Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates in NATURE
  • 1990-11 The human VAV proto-oncogene maps to chromosome region 19p12→19p13.2 in HUMAN GENETICS
  • 1989 Early Detection of ras Oncogenes Activated by Chemical Carcinogentreatment in RAS ONCOGENES
  • 1986-02 A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences in NATURE
  • 1986 Activation of H-ras-1 Oncogenes by Chemical Carcinogens in MECHANISMS OF DNA DAMAGE AND REPAIR
  • 1985-05 Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats in NATURE
  • 1985 Molecular Assays for Detection of ras Oncogenes in Human and Animal Tumors in INTERNATIONAL SYMPOSIUM: RETROVIRUSES AND HUMAN PATHOLOGY
  • JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "affiliation": [
          {
            "affiliation": {
              "id": "http://www.grid.ac/institutes/grid.7719.8", 
              "type": "Organization"
            }, 
            "isCurrent": true, 
            "type": "OrganizationRole"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.21729.3f", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.413448.e", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.170205.1", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.412041.2", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.417768.b", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.4714.6", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.16750.35", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.254748.8", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.418281.6", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.418021.e", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.42505.36", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.428472.f", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.4711.3", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.248762.d", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.420232.5", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.4367.6", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.38142.3c", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.510933.d", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.48336.3a", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.5515.4", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.419971.3", 
            "type": "Organization"
          }, 
          {
            "id": "http://www.grid.ac/institutes/grid.250671.7", 
            "type": "Organization"
          }
        ], 
        "familyName": "Barbacid", 
        "givenName": "Mariano", 
        "id": "sg:person.0101555544.84", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0101555544.84"
        ], 
        "sdDataset": "persons", 
        "sdDatePublished": "2022-12-01T07:13", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/person/person_88.jsonl", 
        "type": "Person"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/person.0101555544.84'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/person.0101555544.84'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/person.0101555544.84'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/person.0101555544.84'


     

    This table displays all metadata directly associated to this object as RDF triples.

    60 TRIPLES      10 PREDICATES      33 URIs      7 LITERALS      2 BLANK NODES

    Subject Predicate Object
    1 sg:person.0101555544.84 schema:affiliation N1efe4495a6bb4ae48cb902f40c5d8e5a
    2 grid-institutes:grid.16750.35
    3 grid-institutes:grid.170205.1
    4 grid-institutes:grid.21729.3f
    5 grid-institutes:grid.248762.d
    6 grid-institutes:grid.250671.7
    7 grid-institutes:grid.254748.8
    8 grid-institutes:grid.38142.3c
    9 grid-institutes:grid.412041.2
    10 grid-institutes:grid.413448.e
    11 grid-institutes:grid.417768.b
    12 grid-institutes:grid.418021.e
    13 grid-institutes:grid.418281.6
    14 grid-institutes:grid.419971.3
    15 grid-institutes:grid.420232.5
    16 grid-institutes:grid.42505.36
    17 grid-institutes:grid.428472.f
    18 grid-institutes:grid.4367.6
    19 grid-institutes:grid.4711.3
    20 grid-institutes:grid.4714.6
    21 grid-institutes:grid.48336.3a
    22 grid-institutes:grid.510933.d
    23 grid-institutes:grid.5515.4
    24 schema:familyName Barbacid
    25 schema:givenName Mariano
    26 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0101555544.84
    27 schema:sdDatePublished 2022-12-01T07:13
    28 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    29 schema:sdPublisher Nfee0bccdcd1d43c8a850713b391511ce
    30 sgo:license sg:explorer/license/
    31 sgo:sdDataset persons
    32 rdf:type schema:Person
    33 N1efe4495a6bb4ae48cb902f40c5d8e5a schema:affiliation grid-institutes:grid.7719.8
    34 sgo:isCurrent true
    35 rdf:type schema:OrganizationRole
    36 Nfee0bccdcd1d43c8a850713b391511ce schema:name Springer Nature - SN SciGraph project
    37 rdf:type schema:Organization
    38 grid-institutes:grid.16750.35 schema:Organization
    39 grid-institutes:grid.170205.1 schema:Organization
    40 grid-institutes:grid.21729.3f schema:Organization
    41 grid-institutes:grid.248762.d schema:Organization
    42 grid-institutes:grid.250671.7 schema:Organization
    43 grid-institutes:grid.254748.8 schema:Organization
    44 grid-institutes:grid.38142.3c schema:Organization
    45 grid-institutes:grid.412041.2 schema:Organization
    46 grid-institutes:grid.413448.e schema:Organization
    47 grid-institutes:grid.417768.b schema:Organization
    48 grid-institutes:grid.418021.e schema:Organization
    49 grid-institutes:grid.418281.6 schema:Organization
    50 grid-institutes:grid.419971.3 schema:Organization
    51 grid-institutes:grid.420232.5 schema:Organization
    52 grid-institutes:grid.42505.36 schema:Organization
    53 grid-institutes:grid.428472.f schema:Organization
    54 grid-institutes:grid.4367.6 schema:Organization
    55 grid-institutes:grid.4711.3 schema:Organization
    56 grid-institutes:grid.4714.6 schema:Organization
    57 grid-institutes:grid.48336.3a schema:Organization
    58 grid-institutes:grid.510933.d schema:Organization
    59 grid-institutes:grid.5515.4 schema:Organization
    60 grid-institutes:grid.7719.8 schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...