Mariano Barbacid


Ontology type: schema:Person     


Person Info

NAME

Mariano

SURNAME

Barbacid

Publications in SciGraph latest 50 shown

  • 2019-04 Effects of a Ketogenic Diet on [18F]FDG-PET Imaging in a Mouse Model of Lung Cancer in MOLECULAR IMAGING AND BIOLOGY
  • 2019-02 RAF inhibitor PLX8394 selectively disrupts BRAF dimers and RAS-independent BRAF-mutant-driven signaling in NATURE MEDICINE
  • 2017-08 Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS in NATURE
  • 2017-08 A Braf kinase-inactive mutant induces lung adenocarcinoma in NATURE
  • 2017-04 In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma in ONCOGENE
  • 2016-03 Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma in NATURE MEDICINE
  • 2016-02 Modeling K-Ras-driven lung adenocarcinoma in mice: preclinical validation of therapeutic targets in JOURNAL OF MOLECULAR MEDICINE
  • 2014-10 Reply: ‘Comments on Stromal disrupting effects of nab-paclitaxel in pancreatic cancer’ in BRITISH JOURNAL OF CANCER
  • 2014-05 Ras signaling is essential for skin development in ONCOGENE
  • 2014 Mouse Models of RAS-Induced Tumors and Developmental Disorders in RAS SUPERFAMILY SMALL G PROTEINS: BIOLOGY AND MECHANISMS 1
  • 2013-12 Reversible, interrelated mRNA and miRNA expression patterns in the transcriptome of Rasless fibroblasts: functional and mechanistic implications in BMC GENOMICS
  • 2013-08 Stromal disrupting effects of nab-paclitaxel in pancreatic cancer in BRITISH JOURNAL OF CANCER
  • 2011-12 Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2011-01 Upregulation of miR-21 by Ras in vivo and its role in tumor growth in ONCOGENE
  • 2010-11-13 Updating the Mammalian Cell Cycle: The Role of Interphase Cdks in Tissue Homeostasis and Cancer in TWO FACES OF EVIL: CANCER AND NEURODEGENERATION
  • 2010-06 DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS in NATURE STRUCTURAL & MOLECULAR BIOLOGY
  • 2010-01 Cdk2 suppresses cellular senescence induced by the c-myc oncogene in NATURE CELL BIOLOGY
  • 2009-03 Cell cycle, CDKs and cancer: a changing paradigm in NATURE REVIEWS CANCER
  • 2007-08 Cdk1 is sufficient to drive the mammalian cell cycle in NATURE
  • 2007-06 p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation in NATURE GENETICS
  • 2006-05 Cyclin-dependent kinase 2 is dispensable for normal centrosome duplication but required for oncogene-induced centrosome overduplication in ONCOGENE
  • 2005-08 Tumour biology: Senescence in premalignant tumours in NATURE
  • 2004-09 The European dimension for the mouse genome mutagenesis program in NATURE GENETICS
  • 2004-04 La necesidad de un Pacto de Estado por la Ciencia en España in CLINICAL AND TRANSLATIONAL ONCOLOGY
  • 2004-04 Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1 diabetes in DIABETOLOGIA
  • 2003-09 Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice in NATURE GENETICS
  • 2003-09 RAS oncogenes: The first 30 years in NATURE REVIEWS CANCER
  • 2003-08 Genetic rescue of Cdk4 null mice restores pancreatic β-cell proliferation but not homeostatic cell number in ONCOGENE
  • 2003-06 RAS oncogenes: the first 30 years in NATURE REVIEWS CANCER
  • 2003 Driving the Cell Cycle to Cancer in NEW TRENDS IN CANCER FOR THE 21STCENTURY
  • 2001-12 Milestones in cell division : To cycle or not to cycle: a critical decision in cancer in NATURE REVIEWS CANCER
  • 2001-06 Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling in NATURE IMMUNOLOGY
  • 1999-05 Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in β-islet cell hyperplasia in NATURE GENETICS
  • 1997-11 Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation in ONCOGENE
  • 1997-10 Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system in CELL AND TISSUE RESEARCH
  • 1997-07 A giant protein that stimulates guanine nucleotide exchange on ARF1 and Rab proteins forms a cytosolic ternary complex with clathrin and Hsp70 in ONCOGENE
  • 1997-05 ERRATUM in CLINICAL & EXPERIMENTAL METASTASIS
  • 1997-01 Evaluation of fluorometric and zymographic methods as activity assays for stromelysins and gelatinases in CLINICAL & EXPERIMENTAL METASTASIS
  • 1997 Genetic analysis of the role of Eph receptors in the development of the mammalian nervous system in MOLECULAR BASES OF AXONAL GROWTH AND PATHFINDING
  • 1996-07 Renal agenesis and the absence of enteric neurons in mice lacking GDNF in NATURE
  • 1995-03 Defective T-cell receptor signalling and positive selection of Vav-deficient CD4+CDS+thymocytes in NATURE
  • 1994-03 Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements in NATURE
  • 1994-03 Severe sensory and sympathetic neuropathies in mice carrying a disrupted Trk/NGF receptor gene in NATURE
  • 1992-03 Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates in NATURE
  • 1990-11 The human VAV proto-oncogene maps to chromosome region 19p12→19p13.2 in HUMAN GENETICS
  • 1989 Early Detection of ras Oncogenes Activated by Chemical Carcinogentreatment in RAS ONCOGENES
  • 1986-02 A human oncogene formed by the fusion of truncated tropomyosin and protein tyrosine kinase sequences in NATURE
  • 1986 Activation of H-ras-1 Oncogenes by Chemical Carcinogens in MECHANISMS OF DNA DAMAGE AND REPAIR
  • 1985-05 Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats in NATURE
  • 1985 Molecular Assays for Detection of ras Oncogenes in Human and Animal Tumors in INTERNATIONAL SYMPOSIUM: RETROVIRUSES AND HUMAN PATHOLOGY
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