B Cell Receptor Modification In B Cells


Ontology type: sgo:Patent     


Patent Info

DATE

2019-02-07T00:00

AUTHORS

VOSS JAMES EVEN , ANDRABI RAIEES , BURTON DENNIS R , HUANG DELI , GONZALEZ-MARTIN ALICIA

ABSTRACT

Methods and systems are described herein for generating engineered B cells with modified immunoglobulin genes. The modified immunoglobulin genes encode modified immunoglobulins that can have high affinity for antigens, including antigens that are variable such the types of antigens on various pathogens that can escape mammalian immune responses.

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "VOSS JAMES EVEN", 
        "type": "Person"
      }, 
      {
        "name": "ANDRABI RAIEES", 
        "type": "Person"
      }, 
      {
        "name": "BURTON DENNIS R", 
        "type": "Person"
      }, 
      {
        "name": "HUANG DELI", 
        "type": "Person"
      }, 
      {
        "name": "GONZALEZ-MARTIN ALICIA", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/labinvest.3700472", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014327251", 
          "https://doi.org/10.1038/labinvest.3700472"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/gene.2012.12", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021553554", 
          "https://doi.org/10.1038/gene.2012.12"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/srep03355", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040966448", 
          "https://doi.org/10.1038/srep03355"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrmicro1819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031201834", 
          "https://doi.org/10.1038/nrmicro1819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature23301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1090830406", 
          "https://doi.org/10.1038/nature23301"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nri2635", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034816083", 
          "https://doi.org/10.1038/nri2635"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10696", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016437859", 
          "https://doi.org/10.1038/nature10696"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/354308a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006692018", 
          "https://doi.org/10.1038/354308a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2013.143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016534425", 
          "https://doi.org/10.1038/nprot.2013.143"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nsmb.1566", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036779001", 
          "https://doi.org/10.1038/nsmb.1566"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10373", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044845665", 
          "https://doi.org/10.1038/nature10373"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/342385a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049183400", 
          "https://doi.org/10.1038/342385a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1186/1471-2105-13-31", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047017534", 
          "https://doi.org/10.1186/1471-2105-13-31"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2019-02-07T00:00", 
    "description": "

Methods and systems are described herein for generating engineered B cells with modified immunoglobulin genes. The modified immunoglobulin genes encode modified immunoglobulins that can have high affinity for antigens, including antigens that are variable such the types of antigens on various pathogens that can escape mammalian immune responses.

", "id": "sg:patent.WO-2019028417-A1", "name": "B CELL RECEPTOR MODIFICATION IN B CELLS", "recipient": [ { "id": "http://www.grid.ac/institutes/grid.214007.0", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/WO-2019028417-A1" ], "sdDataset": "patents", "sdDatePublished": "2022-10-01T07:03", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-springernature-scigraph/baseset/20221001/entities/gbq_results/patent/patent_33.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.WO-2019028417-A1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.WO-2019028417-A1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.WO-2019028417-A1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.WO-2019028417-A1'


 

This table displays all metadata directly associated to this object as RDF triples.

93 TRIPLES      14 PREDICATES      28 URIs      8 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.WO-2019028417-A1 schema:about anzsrc-for:11
2 anzsrc-for:1107
3 schema:author N0973f8b797ef4faa8b2c3050c83d1557
4 schema:citation sg:pub.10.1038/342385a0
5 sg:pub.10.1038/354308a0
6 sg:pub.10.1038/gene.2012.12
7 sg:pub.10.1038/labinvest.3700472
8 sg:pub.10.1038/nature10373
9 sg:pub.10.1038/nature10696
10 sg:pub.10.1038/nature23301
11 sg:pub.10.1038/nprot.2013.143
12 sg:pub.10.1038/nri2635
13 sg:pub.10.1038/nrmicro1819
14 sg:pub.10.1038/nsmb.1566
15 sg:pub.10.1038/srep03355
16 sg:pub.10.1186/1471-2105-13-31
17 schema:datePublished 2019-02-07T00:00
18 schema:description <p num="0000">Methods and systems are described herein for generating engineered B cells with modified immunoglobulin genes. The modified immunoglobulin genes encode modified immunoglobulins that can have high affinity for antigens, including antigens that are variable such the types of antigens on various pathogens that can escape mammalian immune responses.</p>
19 schema:name B CELL RECEPTOR MODIFICATION IN B CELLS
20 schema:recipient grid-institutes:grid.214007.0
21 schema:sameAs https://app.dimensions.ai/details/patent/WO-2019028417-A1
22 schema:sdDatePublished 2022-10-01T07:03
23 schema:sdLicense https://scigraph.springernature.com/explorer/license/
24 schema:sdPublisher Ne434f0b4ad324cfa94cbbb44682c5c7f
25 sgo:license sg:explorer/license/
26 sgo:sdDataset patents
27 rdf:type sgo:Patent
28 N0973f8b797ef4faa8b2c3050c83d1557 rdf:first Nab8618a11ded46449b570f9e353ecd84
29 rdf:rest N0c35da7f4b1d4fefa9dc8adfaa3c46ca
30 N0c35da7f4b1d4fefa9dc8adfaa3c46ca rdf:first N8e51759da5bc49ae939c9ab2c3dbfe2e
31 rdf:rest Nf6d6b6c12252452c9f87de09b9546675
32 N1c17efe7412c4466a14130a906623073 schema:name BURTON DENNIS R
33 rdf:type schema:Person
34 N20a35e742ec24145b6c797a8e5f24a50 schema:name HUANG DELI
35 rdf:type schema:Person
36 N8e51759da5bc49ae939c9ab2c3dbfe2e schema:name ANDRABI RAIEES
37 rdf:type schema:Person
38 N9a2ab289c8fc4892bab69b2731e89f34 rdf:first Nfd4efa2a942d426f9e4fbd11d2761133
39 rdf:rest rdf:nil
40 N9d9cc40e6c4d4fe094c3692f3d525a9c rdf:first N20a35e742ec24145b6c797a8e5f24a50
41 rdf:rest N9a2ab289c8fc4892bab69b2731e89f34
42 Nab8618a11ded46449b570f9e353ecd84 schema:name VOSS JAMES EVEN
43 rdf:type schema:Person
44 Ne434f0b4ad324cfa94cbbb44682c5c7f schema:name Springer Nature - SN SciGraph project
45 rdf:type schema:Organization
46 Nf6d6b6c12252452c9f87de09b9546675 rdf:first N1c17efe7412c4466a14130a906623073
47 rdf:rest N9d9cc40e6c4d4fe094c3692f3d525a9c
48 Nfd4efa2a942d426f9e4fbd11d2761133 schema:name GONZALEZ-MARTIN ALICIA
49 rdf:type schema:Person
50 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
51 rdf:type schema:DefinedTerm
52 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
53 rdf:type schema:DefinedTerm
54 sg:pub.10.1038/342385a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049183400
55 https://doi.org/10.1038/342385a0
56 rdf:type schema:CreativeWork
57 sg:pub.10.1038/354308a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006692018
58 https://doi.org/10.1038/354308a0
59 rdf:type schema:CreativeWork
60 sg:pub.10.1038/gene.2012.12 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021553554
61 https://doi.org/10.1038/gene.2012.12
62 rdf:type schema:CreativeWork
63 sg:pub.10.1038/labinvest.3700472 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014327251
64 https://doi.org/10.1038/labinvest.3700472
65 rdf:type schema:CreativeWork
66 sg:pub.10.1038/nature10373 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044845665
67 https://doi.org/10.1038/nature10373
68 rdf:type schema:CreativeWork
69 sg:pub.10.1038/nature10696 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016437859
70 https://doi.org/10.1038/nature10696
71 rdf:type schema:CreativeWork
72 sg:pub.10.1038/nature23301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1090830406
73 https://doi.org/10.1038/nature23301
74 rdf:type schema:CreativeWork
75 sg:pub.10.1038/nprot.2013.143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016534425
76 https://doi.org/10.1038/nprot.2013.143
77 rdf:type schema:CreativeWork
78 sg:pub.10.1038/nri2635 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034816083
79 https://doi.org/10.1038/nri2635
80 rdf:type schema:CreativeWork
81 sg:pub.10.1038/nrmicro1819 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031201834
82 https://doi.org/10.1038/nrmicro1819
83 rdf:type schema:CreativeWork
84 sg:pub.10.1038/nsmb.1566 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036779001
85 https://doi.org/10.1038/nsmb.1566
86 rdf:type schema:CreativeWork
87 sg:pub.10.1038/srep03355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040966448
88 https://doi.org/10.1038/srep03355
89 rdf:type schema:CreativeWork
90 sg:pub.10.1186/1471-2105-13-31 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047017534
91 https://doi.org/10.1186/1471-2105-13-31
92 rdf:type schema:CreativeWork
93 grid-institutes:grid.214007.0 schema:Organization
 




Preview window. Press ESC to close (or click here)


...