Nanoparticle Platform For Antibody And Vaccine Delivery


Ontology type: sgo:Patent     


Patent Info

DATE

2019-02-07T00:00

AUTHORS

JULIEN JEAN-PHILIPPE , SICARD TAYLOR , SEMESI ANTHONY , TREANOR BEBHINN , ZHAO TIANTIAN , RUJAS DIEZ EDURNE

ABSTRACT

A fusion protein comprises a nanocage monomer; and an antibody or fragment thereof linked to the nanocage monomer, the antibody or fragment thereof comprising a first member of a binding pair; wherein a plurality of the fusion proteins self-assemble to form a nanocage in which a plurality of the antibodies or fragments thereof decorate the exterior surface of the nanocage, whereby the first member of the binding pair is exposed for interacting with a second member of a binding pair. More... »

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